16266938
Descripción
Test por Rochelle T, actualizado hace más de 1 año
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Creado por Rochelle T
hace casi 6 años
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Pregunta 1
Pregunta
The Nobel Prive this year in Physiology or Medicine went to research on:
Respuesta
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Lasers
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Climate Change
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Immunotherapy and cancer
-
Improving the welfare of children
-
Discovery of telomers
Pregunta 2
Pregunta
The max RF value between 2 genes in coupling is 0.3
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True
-
False
Pregunta 3
Pregunta
Which of the following does not represent an aneuploid cell?
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a triploid cell
-
a cell with trisomy
-
a cell with monosomy
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a cell from an individual with Klinefelter syndrome
-
a cell from an individual with Jacob syndrome
Pregunta 4
Pregunta
A child with Down Syndrome could result from
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non-disjunction during meiosis 2
-
non-disjunction during transcription
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non-disjunction during translation
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non-disjunction during meiosis 1
-
two of the above
Pregunta 5
Pregunta
Live humans can be monosomic for sex chromosomes, but not monosomic for autosomes
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true
-
false
Pregunta 6
Pregunta
Use the following conditions to answer the question:
A. Turner Syndrome
B. Edwards syndrome
C. Triple X
D. Polypoidy
E. None of the above
The Human condition where cells have an extra autosome is called-----
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A
-
B
-
C
-
D
-
E
Pregunta 7
Pregunta
Use the following conditions to answer the question:
A. Turner Syndrome
B. Edwards syndrome
C. Triple X
D. Polypoidy
E. None of the above
The Human condition where cells have a missing sex chromosome is -----
Respuesta
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A
-
B
-
C
-
D
-
E
Pregunta 8
Pregunta
Use the following conditions to answer the question:
A. Turner Syndrome
B. Edwards syndrome
C. Triple X
D. Polypoidy
E. None of the above
This is seen in some plant cells
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A
-
B
-
C
-
D
-
E
Pregunta 9
Pregunta
Guanylic acid is a -------
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base
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nucleoside
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ribonucleotide
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amino-acid
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none of the above
Pregunta 10
Pregunta
What is the structure of B DNA?
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Left-handed double helix
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right-handed alpha helix
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left handed double helix with 10 bp per turn
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right-handed double helix
-
none of the above
Pregunta 11
Pregunta
The width of DNA is 20 Angstroms
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true
-
false
Pregunta 12
Pregunta
Based on Griffith's experiment, the following would kill the mouse
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heat killed IIIS bacteria and live IIR
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heat killed IIR
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heat killed IIR and live IIIS
-
two of the above
-
all of the answers are correct
Pregunta 13
Pregunta
Which of the following represents DNA synthesis?
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n(AA) --> (AA)n
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n(dXTP)---> (dXMP)n + nPiP
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n(XTP)---> (XMP)n + nPiP
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n(dXMP)---> (dXMP)n + nPiP
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n(dXMP)---> (XTP)n + nPiP
Pregunta 14
Pregunta
Which of the following is/are True regarding DNA polymerase 1?
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it has 5' to 3' polymerase activity
-
it has ligase activity
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it has 3' to 5' exonuclease activity
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it has telomerase activity
-
two of the above
Pregunta 15
Pregunta
Meselson and Stahl provided experimental evidence for the conservative model of replication.
Respuesta
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True
-
False
Pregunta 16
Pregunta
Helicase-----while-----topisomerase-------
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breaks phosphodiester bonds/ breaks hydrogen bonds
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breaks hydrogen bonds/ breaks phosphodiester bonds
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breaks peptide bonds/ breaks phosphodiester bonds
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breaks ionic bonds/ breaks phosphodiester bonds
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none of the above
Pregunta 17
Pregunta
Which of the following statements is/are true concerning DNA replication?
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both leading and lagging strands are synthesized in a 3' to a 5' direction
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the leading strand is synthesized in a 5' to 3' direction, the lagging strand in a 3' to 5' direction
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both leading and laggging strands are synthesized in a 5' to 3' direction
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DNA polymerase 2 is responsible for the bilk of the nucleotide ploymerization
-
none of the above
Pregunta 18
Pregunta
After receiving a sample of cells, you determine that the cells contain tus. What can you conclude about these cells?
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they are prokaryotes
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they might be cancer cells
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they might be stem cells
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they are gametes
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B and C are possible
Pregunta 19
Pregunta
The following are TRUE regarding DNA replication in Prokaryotes and Eukaryotes
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Replication is semi-conservative
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replication is bi-directional
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replication uses ribosomes
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replication uses promoter sequences
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two of the above
Pregunta 20
Pregunta
If a DNA molecule has 200 bp then it is--------long
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3.4 nm
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6.8 Angstroms
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68 nm
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20 nm
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none of the above
Pregunta 21
Pregunta
According to Chargaff's rules if a DNA molecule contains 34% C, then which of the following is true?
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Total pyrimidines is 50%
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22% are adenine
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the four bases are present at 25%
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the total purines is 44%
Pregunta 22
Pregunta
The origins of replication in eukaryotes are called ------ and one would expect to find------
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Pribnow box/ A and T bases
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OriC/ DnaA, DnaB and DnaC
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Shine-Delgarno/ start codon
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ARS/ histones
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all of the above
Pregunta 23
Pregunta
Telomerase extends the 3' single stranded DNA overhand in replication
Respuesta
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true
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false
Pregunta 24
Pregunta
The difference in transcription between eukaryotes and prokaryotes are:
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one uses DNA pol 1 2 and 3 and the other uses different DNA pol enzymes
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one uses primase and the other does not
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one uses chromatin remodeling complexes and the other does not
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one always transbries both the sense and antisense strand of the gene while the other does not
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all of the above
Pregunta 25
Pregunta
The core promoter in prokaryotes is called
Respuesta
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kozak sequence
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OriC
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Pribnow box
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rut sequence
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operator sequence
Pregunta 26
Pregunta
Transcription termination in prokaryotes sometimes requires:
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rho, rut and tus
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stem loop, telomeres and Nus A
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term sigma factor and RNA pol 2
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RNA pol3 and specific transcription factors
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none of the above
Pregunta 27
Pregunta
Which is the sense strand?
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Top Stand (AB)
-
Bottom Strand (CD)
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Both
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neither
Pregunta 28
Pregunta
In the diagram, the following are true
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A refers to 3'
-
C refers to 3'
-
B refers to 5'
-
D refers to 5'
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above of the above
Pregunta 29
Pregunta
What is an example of a ribozyme?
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rRNA
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tRNA
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intronic RNA
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miRNA
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all of the above
Pregunta 30
Pregunta
Enhancer sequences usually bind activators and they are transcribed
Respuesta
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true
-
false
Pregunta 31
Pregunta
in prokaryotes the small ribosomal subunit is----while in the eukaryotes it is-----
Respuesta
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20S, 40S
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20S, 50S
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30S, 40S
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30S, 50S
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70S, 80S
Pregunta 32
Pregunta
Some of the rRNAs in prokaryotes are ---- while some of the rRNAs in eukaryotes are -----
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16S rRNA and 18S rRNA / 23S rRNA and 28S rRNA
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16S rRNA and 5S rRNA / 18S rRNA and 28S rRNA
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23S rRNA and 28S rRNA / 16S rRNA and 28S rRNA
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18S rRNA and 5S rRNA / 29S rRNA and 38S rRNA
-
none of the above
Pregunta 33
Pregunta
Some of the steps in 5' capping of mRNA involve:
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removing RNA and adding GMP
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Removing DNA and adding ATP
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Adding DNA and transfering a methyl group
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removing a phosphate and adding GMP
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adding poly A
Pregunta 34
Pregunta
In eukaryotes, tRNA ------
Respuesta
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undergoes RNA processing
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has unusual bases
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is transported out of the cytoplasm
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has codon sequences
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three of the above
Pregunta 35
Pregunta
In prokaryotic translation, the first charged tRNA enters into the ribosomal P site and carries the amino acid fmet.
Respuesta
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true
-
false
Pregunta 36
Pregunta
Which of the following amino acids exhibits " degeneracy" in the genetic code that CAN be explained by the "Wobble Hypothesis" alone?
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Tryptophan Trp
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Arginine Arg
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Phenylalanine Phe
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Glutamine Gln
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Two of the above
Pregunta 37
Pregunta
The best description of isoaccepting tRNA molecules is
Respuesta
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different anticodons but same amino acids
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different codons but same amino acids
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different anticodons and different amino acids
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different codons and different amino acids
-
all of the above
Pregunta 38
Pregunta
Choose the following answers:
A. Kozak sequence
B. the A site in the ribosome
C. release factors
D. uncharged tRNA
E. none of the answers are correct
Is important in binding to 18S rRNA
Respuesta
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A
-
B
-
C
-
D
-
E
Pregunta 39
Pregunta
Choose the following answers:
A. Kozak sequence
B. the A site in the ribosome
C. release factors
D. uncharged tRNA
E. none of the answers are correct
Occupies the E site in translation
Respuesta
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A
-
B
-
C
-
D
-
E
Pregunta 40
Pregunta
A possible mechanism of action of an antibiotic could be:
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inhibition of DNA pol (any greek letter)
-
inhibition of DNA gyrase
-
inhibition prokaryotic peptidyl transferase
-
inhibition of movement of RNA out to cytoplasm
-
two of the answers are correct
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