Pharmacology MCQs 2- 4th Year- PMU

Question

Functional antagonists of histamine are

Answer 1

corticosteroids

Answer 2

opoid analgesics

Answer 3

neuroepileptics

Answer 4

Loratidine (Claritin)

Answer 5

Fexofenadine (Telfast)

Answer 6

Cetirizine (Zodac)

Answer 7

Dimenhydrinate (Vomacur)

Answer 8

Omeprazole (Sopral)

Answer 9

Ranitidine (Zantac)

Answer 10

Bismuth collodial (De-nol)

Answer 11

Famotidine (Famultran)

Answer 12

Sumatripan (Imigran)

Answer 13

Ranitidine (Zantac)

Answer 14

Loratidine (Claritin)

Answer 15

Naratripan (Naramig)

Answer 16

Naratripan (Naramig)

Answer 17

Ondansetron (Zofran)

Answer 18

Clozapine (Leponex)

Answer 19

Desloratidine (Aerius)

Answer 20

they reversibly block activated sodium channels

Answer 21

they block the potassium channels

Answer 22

they block the conduction of action potentials along axons

Answer 23

they block the β-receptors in the cell membrane

Answer 24

Mepivacaine

Answer 25

Beta-methyldigoxin (Lanitop)

Answer 26

Theophyllin

Answer 27

positive inotropic

Answer 28

negative chronotropic

Answer 29

negative dromotropic

Answer 30

positive batmotropic

Answer 31

stimulation of M-cholinoreceptors

Answer 32

inhibition of Na+/K+-ATPase

Answer 33

inhibition of enzyme phosphodiesterase

Answer 34

an increase in the cyclic adenosine monophosphate

Answer 35

Acetyldigoxin

Answer 36

Beta-methyldigoxin (Lanitop)

Answer 37

Digitalin (Digitoxin)

Answer 38

loss of appetite, vomiting

Answer 39

muscle weakness, tremors

Answer 40

hallucinations, yellowish vision (xanthopsia)

Answer 41

ventricular extrasystoles, atrioventricular block

Answer 42

Propranolol

Answer 43

Amiodarone

Answer 44

Quinidine sulfate

Answer 45

affect the generation and induction/conduction of action potential in the heart

Answer 46

slow conduction of action potential

Answer 47

blocking of cholinesterase

Answer 48

changes in trsport of K+, Na+, or Ca++ ions

Answer 49

sinus bradycardia

Answer 50

sinus tachycardia

Answer 51

opthalmological diseases

Answer 52

thyroid gland dysfunction

Answer 53

Glyceryl trinitrate (Nitroglycerin)

Answer 54

Subiingual spray containing lsosorbide-dinitrat (lsoket spray)

Answer 55

Tablets containing Isosorbide-dinitrat (lsodinit)

Answer 56

Tablets containing Isosorbide-5-mononitrat (Monisid)

Answer 57

release of nitric oxide

Answer 58

direct vasodilation

Answer 59

blocking the enzyme phosphodiesterase

Answer 60

activation of the enzyme adenilatcyclase

Answer 61

tachycardia

Answer 62

headache and flushing

Answer 63

hypertension

Answer 64

Nifedipine

Answer 65

Felodipine

Answer 66

tachycardia

Answer 67

bradycardia

Answer 68

swelling of the ankles

Answer 69

Bradycardia

Answer 70

Tachycardia

Answer 71

Constipation

Answer 72

Heart failure

Answer 73

Papaverini hydrochloridum

Answer 74

Pentoxifiyllin (Agapurin)

Answer 75

Cinnarizin (Stugeron)

Answer 76

Drotaverini (No-spa)

Answer 77

vasodilation

Answer 78

platelet aggregation inhibition

Answer 79

antispasmodic

Answer 80

antianginal

Answer 81

Bezafibrate (Bezalip)

Answer 82

Atorvastatin (Sortis)

Answer 83

Simvastatin (Zooor)

Answer 84

Cholestyramine (Questran)

Answer 85

inhibit HMG-CoA-reductase

Answer 86

inhibits the deposition of cholesterol in the blood vessel wall

Answer 87

accelerate the elimination of cholesterol

Answer 88

inhibit the synthesis of Cholesterol and LDL

Answer 89

gastrointestinal disorders

Answer 90

hypertension

Answer 91

hepatotoxicity

Answer 92

inhibits the synthesis of Cholesterol

Answer 93

inhibits the intestinal absorption of Cholesterol

Answer 94

enhances the elimination of Cholesterol

Answer 95

blocks the LDL receptors

Answer 96

antihypertensive

Answer 97

antiarrhythmic

Answer 98

regression of left ventricular hypertrophy

Answer 99

nephroprotective

Answer 100

hyperglycaemia

Answer 101

hyperkalemia

Answer 102

hypotension

Answer 103

heart failure

Answer 104

ventricular extrasystoles

Answer 105

hypertension

Answer 106

acute angina attack

Answer 107

Telmisartan

Answer 108

hypoglycaemia

Answer 109

bronchoconstriction

Answer 110

tachycardia

Answer 111

peripheral vascular spasms

Answer 112

hyperkalemia

Answer 113

hypokalemia

Answer 114

hyperglycaemia

Answer 115

hyperuricemia

Answer 116

Prazosin (Minipress)

Answer 117

Enalapril (Renitec)

Answer 118

Doxazosin.(Cardura)

Answer 119

Diltiazem (Aldizem)

Answer 120

orthostatic hypotension

Answer 121

bronchoconstriction

Answer 122

retention of sodium and water

Answer 123

bradycardia

Answer 124

prostatic hypertrophy

Answer 125

tachycardia

Answer 126

hypertension

Answer 127

angina pectoris

Answer 128

glomerulus

Answer 129

loop of Henle

Answer 130

proximal convoluted tubule

Answer 131

distal convoluted tubule

Answer 132

Hydrochlorthiazide

Answer 133

lndapamide

Answer 134

Spironolactonum

Answer 135

Triamteren

Answer 136

Furosemide

Answer 137

Spironolactone

Answer 138

brain edema

Answer 139

diabetes mellitus

Answer 140

hypertension

Answer 141

chronic heart failure

Answer 142

gynecomastia

Answer 143

hyperkalemia

Answer 144

hepatotoxicity

Answer 145

ototoxicity

Answer 146

participate as a cofactor in the biosynthesis of clotting factors II, VII, IX, X

Answer 147

exists in two natural forms - Vitamin K1 and K2

Answer 148

it is an antidote of heparin

Answer 149

it is used for prevention and treatment of bleeding associated with overdose of indirect anticoagulants

Answer 150

bleeding stomach ulcer

Answer 151

acute myocardial infarction

Answer 152

pulmonary thromboembolism

Answer 153

hemophilia

Answer 154

osteoporosis (by prolonged administration)

Answer 155

reversible alopecia

Answer 156

hemorrhage

Answer 157

allergic reactions

Answer 158

Streptase (Streptokinase)

Answer 159

Sodium chloride

Answer 160

Protamin sulfas

Answer 161

Phytomenadione (Vit. K1)

Answer 162

inhibits factor Xa of coagulation

Answer 163

inhibits factor ll of coagulation

Answer 164

binds to anti-thrombin lll

Answer 165

oppose the action of Vitamin K

Answer 166

good oral absorption

Answer 167

their anticoagulant effect occurs only in vivo

Answer 168

their effect is delayed

Answer 169

their anticoagulant effect occurs only in vitro

Answer 170

Acidum p-aminomethylbenzoicum (PAMBA)

Answer 171

Clopidogrel (PIavix)

Answer 172

Dipyridamole (Antistenocardin)

Answer 173

Acidum acetylsalicylicum (Acetysal)

Answer 174

constipation

Answer 175

epigastric pain, nausea, vomiting

Answer 176

thrombosis

Answer 177

dark-colored gums and teeth

Answer 178

B2-adrenergic agonists

Answer 179

Phosphodiesterase inhibitors

Answer 180

Butyrophenones

Answer 181

Leukotriene receptor antagonists

Answer 182

Salbutamol

Answer 183

Theophylline

Answer 184

Aminophylline

Answer 185

they inhibit MAO

Answer 186

they inhibit acetylcholinesterase

Answer 187

they inhibit phosphodiesterase and increase the cAMP

Answer 188

they inhibit angiotensin converting enzyme

Answer 189

bronchoconstriction

Answer 190

dysphonia (hoarse voice)

Answer 191

oral candidiasis

Answer 192

hypertensive crisis

Answer 193

osteoporosis

Answer 194

leukotriene inhibitor

Answer 195

corticosteroid

Answer 196

cholinergic antagonist

Answer 197

cholinergic agonist

Answer 198

incontinention of urine

Answer 199

tachycardia

Answer 200

hypoglycaemia

Answer 201

they block the M-Choiinoceptors

Answer 202

they are selective, reversible antagonists of the Ieukotriene-1 receptor

Answer 203

they inhibit the enzyme 5-lypoexigenase

Answer 204

they inhibit the angiotensin converting enzyme

Answer 205

Amroxol (Mucosoivan)

Answer 206

Bromhexine

Answer 207

Salbutamol

Answer 208

mucosal protective agents

Answer 209

H1-histamine receptor blockers

Answer 210

H2-histamine receptor blockers

Answer 211

proton pump inhibitors

Answer 212

Roxatidine

Answer 213

Ranitidine

Answer 214

Sucralfate

Answer 215

Omeprazole

Answer 216

H2-histamine receptor blocker

Answer 217

H1-histamine receptor blocker

Answer 218

Proton pump inhibitor

Answer 219

Antimuscarinic drug

Answer 220

inhibition of CYP 450

Answer 221

induction of CYP 450

Answer 222

inhibition of phosphodiesterase

Answer 223

induction of phosphodiasterase

Answer 224

Essentiale

Answer 225

Ademetionine

Answer 226

Oleum Ricini

Answer 227

Hydrocortisone

Answer 228

Methylprednisolone

Answer 229

Fludroconisone

Answer 230

Prednisolon

Answer 231

hypoglycemia

Answer 232

hyperglycemia

Answer 233

reduced calcium absorption

Answer 234

increased protein catabolism

Answer 235

hypotension

Answer 236

anti-inflammatory action

Answer 237

immunosuppressive action

Answer 238

antiallergic action

Answer 239

osteoporosis

Answer 240

diabetes mellitus

Answer 241

hypertension

Answer 242

lnsuman Rapid

Answer 243

hyperglycaemia

Answer 244

hypoglycaemia

Answer 245

inhibition of gluconeogenesis

Answer 246

inhibition of glicogenolysis

Answer 247

hypoglycaemia

Answer 248

hypotension

Answer 249

insulin resistance

Answer 250

block ATP-sensitive K+ channels

Answer 251

stimulate release of endogenous insulin from the pancreas

Answer 252

inhibit gluconeogenesis

Answer 253

lower levels of plasma glucagon

Answer 254

hypotension

Answer 255

weight gain

Answer 256

gastrointestinal

Answer 257

hypoglycaemia

Answer 258

Pioglitazone

Answer 259

Glibenclamide

Answer 260

inhibition of gluconeogenesis

Answer 261

release of insulin from β cells of the pancreas

Answer 262

increased peripheral utilization of glucose

Answer 263

inhibition of glucose absorption from the gastrointestinal tract

Answer 264

gastrointestinal disorders (anorexia, nausea, diarrhoea, metallic, taste)

Answer 265

hypoglycaemia

Answer 266

megaloblastic anemia

Answer 267

lactic acidosis

Answer 268

prolong activity of incretin hormones

Answer 269

release insulin from β cells of the pancreas

Answer 270

do not cause hypoglycaemia

Answer 271

cause weight gain and increased appetite

Answer 272

development of sexual organs

Answer 273

development of the follicular phase of menstrual cycle

Answer 274

development of the luteal phase of menstrual cycle

Answer 275

stimulate uterine contractions

Answer 276

hypertension

Answer 277

thrombosis

Answer 278

carcinogenic effects

Answer 279

nephrotoxicity

Answer 280

thromboembolic disease

Answer 281

probable or certain pregnancy

Answer 282

proven or suspected breast cancer

Answer 283

Suppression of ovulation

Answer 284

Suppression of lutein hormone secretion

Answer 285

Condensation of cervical mucus

Answer 286

Increased secretion of follicle stimulating hormone

Answer 287

Oestrogen dependant tumors

Answer 288

Hyper-coagulation

Answer 289

Liver disease

Answer 290

dermatitis

Answer 291

megaloblastic anemia

Answer 292

spinal cord degeneration and neuropathies

Answer 293

atrophic glossitis

Answer 294

hemeralopia (night blindness)

Answer 295

xerophthalmia (dry eyes)

Answer 296

bradycardia

Answer 297

increased intestinal calcium and phosphate absorption

Answer 298

decreased intestinal calcium and phosphate

Answer 299

stimulation of calcium reabsorption in the kidney

Answer 300

deposition of calcium in bones and teeth (at low dose)

Answer 301

rickets in children

Answer 302

osteomalacia in adults

Answer 303

delayed dentation

Answer 304

hyperglycemia

Answer 305

synthesis of hemoglobin

Answer 306

synthesis of clotting factors II, VII, IX and X

Answer 307

regulation of cholesterol levels

Answer 308

carbohydrate metabolism

Answer 309

neuroepileptics

Answer 310

dopaminergic drugs

Answer 311

antimuscarinic drugs

Answer 312

anxiolytics

Answer 313

MAO A inhibition

Answer 314

Release of dopamine from the stores

Answer 315

MAO B inhibition

Answer 316

Activation of dopamine recepors

Answer 317

Parkinson's disease

Answer 318

Acromegaly

Answer 319

Prolactin-secreting adenomas

Answer 320

Hyperglycemia

Answer 321

Amantadine

Answer 322

Bromocriptine

Answer 323

Selegiline

Answer 324

block of postsynaptic dopamine receptors

Answer 325

activation of dopamine receptors

Answer 326

block of serotonin receptors

Answer 327

block of muscarinic, histamine and adrenergic receptors

Answer 328

block of postsynaptic D4 receptors stronger than D2 receptors

Answer 329

block of 5-HT2 receptors

Answer 330

activation of 5-HT2 receptors

Answer 331

stimulation of muscarinic receptors

Answer 332

antipsychotic effect

Answer 333

antiemetic effect

Answer 334

hypotensive effect

Answer 335

anticonvulsant effect

Answer 336

extrapyramidal syndrome

Answer 337

hyperprolactinemia

Answer 338

drug dependence

Answer 339

postural hypotension

Answer 340

Chlorprothixene

Answer 341

Thioridazine

Answer 342

Haloperidol

Answer 343

enhance the effectiveness of GABA

Answer 344

block of GABA receptors

Answer 345

block of sodium channels

Answer 346

activation of dopamine receptors

Answer 347

tolerance and drug dependence

Answer 348

extrapyramidal side effects

Answer 349

Flumazenil

Answer 350

Chlorpromazine

Answer 351

traumatic shock

Answer 352

acute myocardial infarction

Answer 353

pregnancy, breastfeeding

Answer 354

diseases, associated with respiratory depression

Answer 355

head trauma and brain injury

Answer 356

traumatic shock

Answer 357

Flumazenil

Answer 358

Protamin sulfas

Answer 359

has a spasmolytic effect on the smooth muscles

Answer 360

it is a stronger analgesic than morphine

Answer 361

has a shorter duration of action than morphine

Answer 362

can be used for neuroleptanaigesia

Answer 363

they affect normal body temperature

Answer 364

the antipyretic effect is clue to suppression of PgE synthesis in the hypothalamus

Answer 365

they lower only elevated body temperature (i.e. fever)

Answer 366

intensify heat diffusion

Answer 367

allergic reactions

Answer 368

hyperthermla

Answer 369

agranulocytosis

Answer 370

red coloured urine

Answer 371

antipyretic

Answer 372

anti-inflammatory

Answer 373

antiplatelet

Answer 374

anti-inflammatory

Answer 375

antipyretic

Answer 376

inhibition of phosphodiesterases

Answer 377

blockade of dopamine receptors

Answer 378

inhibition of cyclooxygenase

Answer 379

inhibition of MAO

Answer 380

anti-inflammatory

Answer 381

antiplatelet

Answer 382

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Pharmacology MCQs 2- 4th Year- PMU

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