L13 Asthma

Descripción

PHCY310 Test sobre L13 Asthma, creado por Mer Scott el 09/04/2019.
Mer Scott
Test por Mer Scott, actualizado hace más de 1 año
Mer Scott
Creado por Mer Scott hace más de 5 años
15
0

Resumen del Recurso

Pregunta 1

Pregunta
Asthma is an [blank_start]immune[blank_end] dysfunction, an [blank_start]inflammatory[blank_end] response to a non-pathogenic antigen, therefore an atopic or allergic immune response. • Type [blank_start]I & IV[blank_end] hypersensitivity • Antibody – [blank_start]IgE[blank_end] • [blank_start]Cells[blank_end] – T cells, B cells, mast cells, eosinophils • 2 phases – [blank_start]Sensitisation[blank_end] & inflammation
Respuesta
  • immune
  • inflammatory
  • I & IV
  • IgE
  • Cells
  • sensitisation

Pregunta 2

Pregunta
The [blank_start]Atopic March[blank_end] is the relationship between ashtma, atopic dermatitis(AD) and allergic rhinitis(AR) in children. Children with one [blank_start]atopic[blank_end] condition often will also have [blank_start]another[blank_end]. Food [blank_start]allergy[blank_end] also occurs frequently in children with AD or [blank_start]precedes[blank_end] AD.
Respuesta
  • Atopic March
  • another
  • atopic
  • allergy
  • precedes

Pregunta 3

Pregunta
The first stage of asthma pathology is the [blank_start]sensitisation[blank_end]. A [blank_start]dendritic[blank_end] cell in the lungs encounters an allergen and becomes activated, then travels to a [blank_start]lymph[blank_end] node. T cell activation and [blank_start]proliferation[blank_end] occurs, which releases [blank_start]interleukins[blank_end], and activates B cells. B cells proliferate and release [blank_start]IgE[blank_end] antibodies. The second stage is inflammation. IgE coated/sensitised [blank_start]mast[blank_end] cells and eosinophils in the lungs encounter the allergen and [blank_start]degranulate[blank_end], releasing histamines, proteases, leukotrienes, and prostaglandins which inflame the airways.
Respuesta
  • sensitisation
  • dendritic
  • lymph
  • proliferation
  • interleukins
  • IgE
  • mast
  • degranulate

Pregunta 4

Pregunta
Choose the correct statement.
Respuesta
  • Th2 cells produce cytokines that drive IgE production by B cells
  • Eosinophils release bronchoconstrictors & cytokines
  • Mast cells release mediators that damage cells, and contribute to remodeling

Pregunta 5

Pregunta
Non-atopic asthma, also known as [blank_start]intrinsic[blank_end] asthma, is asthma [blank_start]without[blank_end] atopy. A skin test will be [blank_start]negative[blank_end]. Commonly in women, and usually in adults. There are some differences (debated); the presence of [blank_start]innate[blank_end] lymphoid cells (ILCs), and [blank_start]less[blank_end] IgE, for example. Neutrophilic asthma is another type. It is usually [blank_start]late[blank_end] onset and [blank_start]more[blank_end] severe, and less reversible. There are some differences; [blank_start]Th17[blank_end] rather than Th2, [blank_start]neutrophils[blank_end] rather than eosinophils. It is corticosteroid [blank_start]insensitive[blank_end]. Occupational asthma is another type.
Respuesta
  • intrinsic
  • without
  • negative
  • innate
  • less
  • late
  • more
  • Th17
  • neutrophils
  • insensitive

Pregunta 6

Pregunta
The pathophysiology of asthma includes inflammation, hyperresponsiveness/bronchoconstriction, oedema, and remodelling. Inflammation is quite complex and impacts [blank_start]treatment[blank_end] decision. Hyperresponsiveness is [blank_start]reversible[blank_end] early on and can be measured. Oedema is due to [blank_start]mucus[blank_end] hypersecretion. Airway remodelling is associated with a progressive, [blank_start]irreversible[blank_end] loss of lung function. It includes the thickening of the [blank_start]basement[blank_end] membrane, fibrosis, airway smooth muscle [blank_start]hypertrophy[blank_end] and hyperplasia, angiogenesis, and mucus gland hyperplasia.
Respuesta
  • treatment
  • reversible
  • mucus
  • irreversible
  • basement
  • hypertrophy

Pregunta 7

Pregunta
There is a small but significant dose related association with antibiotics in pediatrics and the development of asthma.
Respuesta
  • True
  • False

Pregunta 8

Pregunta
There is a dose dependent association between paracetamol use in first year of life and asthma, i.e. paracetamol increases the risk of asthma.
Respuesta
  • True
  • False

Pregunta 9

Pregunta
NZ's rate of asthma in the population is:
Respuesta
  • low and stable
  • low and fluctuating
  • high and stable
  • high and fluctuating

Pregunta 10

Pregunta
In conventional asthma treatment and management, we: - Abolish symptoms - [blank_start]Beta agonists[blank_end] (relievers) - Restore best possible airway function - anti-inflammatory drugs ([blank_start]preventers[blank_end]) - Practice allergen [blank_start]avoidance[blank_end]
Respuesta
  • Beta agonists
  • preventers
  • avoidance
Mostrar resumen completo Ocultar resumen completo

Similar

Teorema de Pitágoras
josefa.h.122
Trigonometría
Ana Priego
Fechas y constituciones España
tinctor
Capas de la Tierra
Diego Santos
TARJETAS ESTUDIO CUERPOS GEOMÉTRICOS
Ruth Pérez Sánchez
Cardiología Veterinaria
oscardary
Arte del Renacimiento
maya velasquez
Cómo Usar Fichas para Mejorar el Aprendizaje de tus Alumnos
Diego Santos
Funciones Matemáticas
Nathaly Arias
Título I De los derechos y deberes fundamentales
Paco Tur Fornés
Fases de la guerra
Salustiano Gutiérrez Baena