L43 Therapeutics of IHD

Non-pharmacological treatment for IHD: 1. Nutritional advice: diet that includes a variety of fruits, vegetables, grains, [blank_start]low-fat[blank_end] dairy products, fish, legumes, poultry, and lean meat. Reduce [blank_start]salt[blank_end] if BP elevated. Reduce food with a high glycaemic index if at risk of diabetes. 2. Regular physical activity, [blank_start]weight[blank_end] loss 3. Moderation of alcohol consumption 4. Smoking [blank_start]cessation[blank_end]

Treatment strategy for ACS: - Short-term: 1, [blank_start]Oxygen, morphine, nitrates[blank_end] (inhaled or IV) 2. Revascularisation (e.g. [blank_start]PCI, emergency CABG, fibrinolytics[blank_end]) ‘TIME IS MUSCLE’ 3. Antiplatelets (e.g. [blank_start]aspirin +/- clopidogrel or ticagrelor[blank_end]) 4. Anticoagulants (e.g. [blank_start]UFH or enoxaparin[blank_end]) - Long-term: 1. Control of CV risk factors; 2. Meds: Aspirin (plus clopidogrel or ticagrelor for 6-12 m), beta-blocker, statin, and potentially ACEI/ARB (to prevent left ventricular hypertrophy)

In angina, aspirin, a beta-blocker, a vasodilator (often a nitrate +/- a CCB), and a statin are the mainstay of pharmacological treatment.