Hormonal Secretion

Descripción

University Functional Anatomy and Embryology Test sobre Hormonal Secretion, creado por Charlotte Jakes el 20/04/2020.
Charlotte Jakes
Test por Charlotte Jakes, actualizado hace más de 1 año
Charlotte Jakes
Creado por Charlotte Jakes hace alrededor de 4 años
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Resumen del Recurso

Pregunta 1

Pregunta
Where do endocrine cells secrete their hormones into?
Respuesta
  • Target cells
  • Blood
  • Out of ducts
  • Glands

Pregunta 2

Pregunta
What is a neuroendocrine cell?
Respuesta
  • A cell that released hormones into the blood upon depolarisation
  • A cell that releases neurotransmitter into the blood upon depolarisation
  • A cell that releases hormones across the synaptic cleft upon depolarisation
  • A cell that releases hormones onto neighbouring cells upon depolarisation

Pregunta 3

Pregunta
What type of chemical signalling occurs when a cell targets itself?
Respuesta
  • Autocrine
  • Paracrine
  • Endocrine
  • Neuroendocrine

Pregunta 4

Pregunta
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Respuesta
  • Paracrine
  • Autocrine
  • Endocrine
  • Neuroendocrine

Pregunta 5

Pregunta
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Respuesta
  • Paracrine
  • Autocrine
  • Endocrine
  • Neuroendocrine

Pregunta 6

Pregunta
Which of the following hormones are secreted by neurosecretory cells?
Respuesta
  • Protein/peptide hormones
  • Steroid hormones
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 7

Pregunta
Which of the following hormones are secreted by epithelial tissues?
Respuesta
  • Protein/peptide hormones
  • Steroid hormones
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 8

Pregunta
What gives a hormone a long half-life?
Respuesta
  • Being protein-bound in circulation
  • Being unbound to protein in circulation

Pregunta 9

Pregunta
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Respuesta
  • Cleavage by proteolytic enzymes
  • Cleavage by low pH
  • Packaging into vesicles
  • Release by exocytosis

Pregunta 10

Pregunta
How are active protein/peptide hormones released?
Respuesta
  • Exocytosis stimulated by increase in cytosolic Ca2+
  • Exocytosis stimulated by increase in cytosolic K+
  • Holocrine secretion
  • Apocrine secretion

Pregunta 11

Pregunta
Are protein/peptide hormones protein-bound in circulation?
Respuesta
  • Yes
  • No

Pregunta 12

Pregunta
Which is true of protein hormones in circulation?
Respuesta
  • Long half-life
  • Short half-life

Pregunta 13

Pregunta
The following questions will be about steroid hormones. What are steroid hormones derived from?
Respuesta
  • Cholesterol
  • Proteins
  • Amines
  • DNA

Pregunta 14

Pregunta
Steroid hormones are lipid soluble.
Respuesta
  • True
  • False

Pregunta 15

Pregunta
Steroid hormones are stored in glands.
Respuesta
  • True
  • False

Pregunta 16

Pregunta
Are steroid hormones protein-bound in circulation?
Respuesta
  • Yes
  • No

Pregunta 17

Pregunta
Which is true of steroid hormones?
Respuesta
  • Long half-lives
  • Short half-lives

Pregunta 18

Pregunta
The following questions will be about amine hormones. Most amine hormones are derived from...?
Respuesta
  • Tyrosine
  • Phenylalanine
  • Glutamate
  • Aspartate

Pregunta 19

Pregunta
Thyroid hormones are amine hormones.
Respuesta
  • True
  • False

Pregunta 20

Pregunta
Which subtype of amine hormone is lipid-soluble?
Respuesta
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 21

Pregunta
Which subtype of amine hormone is water-soluble?
Respuesta
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 22

Pregunta
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Respuesta
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 23

Pregunta
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Respuesta
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 24

Pregunta
Which subtype of amine hormones are stored intracellulary in secretory granules?
Respuesta
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Pregunta 25

Pregunta
What are eicosanoids?
Respuesta
  • Local chemical messengers
  • Steroid hormones
  • Protein hormones
  • Transcription regulators

Pregunta 26

Pregunta
What are eicosanoids derived from?
Respuesta
  • Arachidonic acid
  • Diacylglycerol
  • Inositol
  • PIP2

Pregunta 27

Pregunta
Which of the following is an example of an eicosanoid?
Respuesta
  • Prostaglandin
  • Catecholamine
  • Adrenaline
  • Parathyroid hormone

Pregunta 28

Pregunta
Which of the following hormones have intracellular receptors that alter gene transcription?
Respuesta
  • Steroid hormones
  • Thyroid hormones
  • Protein/peptide hormones
  • Glycoproteins
  • Catecholamines (adrenal hormones)

Pregunta 29

Pregunta
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Respuesta
  • Steroid hormones
  • Thyroid hormones
  • Protein/peptide hormones
  • Glycoproteins
  • Catecholamines

Pregunta 30

Pregunta
Drag and drop the correct answers to describe the mechanism of steroid hormones. 1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble. 2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end]. 3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA. 4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA. 5. Binding alters [blank_start]transcription[blank_end] of target genes.
Respuesta
  • lipid
  • water
  • nucleus
  • Golgi apparatus
  • interstitium
  • conformational shape change
  • hydrolysis reaction
  • dimer
  • trimer
  • transcription
  • translation

Pregunta 31

Pregunta
Which of the following can control hormone secretion?
Respuesta
  • Change in plasma ion concentration
  • Change in plasma nutrient concentration
  • Neurotransmitter release from neurones contacting endocrine cells
  • Upstream hormone/paracrine agents acting on endocrine cells
  • Conscious effort
  • Repetitive limb movement
  • Lipolysis

Pregunta 32

Pregunta
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Respuesta
  • Paraventricular nucleus
  • Supraoptic nucleus
  • Neurosecretory cells
  • Optic chiasm
  • Median eminence
  • Infundibular stem
  • Hypophyseal portal vein
  • Pars tuberalis
  • Pars distalis
  • Pars nervosa
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Pregunta 33

Pregunta
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Respuesta
  • Neuroectoderm of the diencephalon
  • Oropharynx ectoderm of the roof of the mouth

Pregunta 34

Pregunta
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Respuesta
  • Neuroectoderm of the diencephalon
  • Oropharynx ectoderm of the roof of the mouth

Pregunta 35

Pregunta
Drag and drop the correct labels to describe the development of the pituitary gland.
Respuesta
  • Neuroectoderm
  • Oropharynx ectoderm
  • Rathke's pouch
  • Developing sphenoid bone
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Pregunta 36

Pregunta
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Respuesta
  • ADH
  • Oxytocin
  • FSH
  • LH
  • ACTH

Pregunta 37

Pregunta
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis. 1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei. 2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells. 3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals. 4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Respuesta
  • cell bodies
  • hypothalamic
  • thalamic
  • cortical
  • axons
  • neuroendocrine
  • endocrine
  • paracrine
  • Herring bodies
  • pituicytes
  • venous blood
  • tissue fluid
  • surrounding CSF

Pregunta 38

Pregunta
What is the effect of ADH?
Respuesta
  • Increased water resorption in the kidney
  • Decreased water resorption in the kidney
  • Increase in uterine contractions
  • Stimulation of the adrenal glands

Pregunta 39

Pregunta
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Respuesta
  • True
  • False

Pregunta 40

Pregunta
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis. 1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones. 2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end]. 3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end]. 4. The hypothalamic hormones control release of anterior pituitary hormones.
Respuesta
  • synthesis
  • hypothalamic
  • neuroendocrine
  • paracrine
  • autocrine
  • median eminence
  • pars tuberalis
  • pars distalis
  • portal blood vessels
  • axons of neuroendocrine cells

Pregunta 41

Pregunta
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Respuesta
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Pregunta 42

Pregunta
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Respuesta
  • Supraoptic nuclei
  • Paraventricular nuclei
  • Superior hypophyseal artery
  • Infundibulum
  • Inferior hypophyseal artery
  • trabecular artery
  • Hypophyseal veins
  • Endocrine cells
  • Anterior pituitary/adenohypophysis
  • Posterior pituitary/neurohypophysis

Pregunta 43

Pregunta
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Respuesta
  • LH
  • FSH
  • ACTH
  • Melanocyte-stimulating hormone
  • Somatotropin/growth hormine
  • Prolactin
  • TSH
  • ADH
  • Oxytocin

Pregunta 44

Pregunta
What do the hypothalamic hypophysiotrophic hormones do?
Respuesta
  • Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
  • Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
  • Increase body temperature
  • Initiate reproductive behaviour

Pregunta 45

Pregunta
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Respuesta
  • Thyrotropin-releasing hormone
  • Dopamine
  • Corticotropin-releasing hormone
  • Gonadotrophin-releasing hormone
  • Growth-hormone releasing hormone
  • Somatostatin
  • Thyrotroph cells
  • Lactotroph cells
  • Corticotroph cells
  • Gonadotroph cells
  • Somatotroph cells
  • Thyroid-stimulating hormone
  • Prolactin
  • Adrenocorticotrophic hormone
  • Luteinising hormone
  • Follicle-stimulating hormone
  • Growth hormone
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