Pregunta 1
Pregunta
Where do endocrine cells secrete their hormones into?
Respuesta
-
Target cells
-
Blood
-
Out of ducts
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Glands
Pregunta 2
Pregunta
What is a neuroendocrine cell?
Respuesta
-
A cell that released hormones into the blood upon depolarisation
-
A cell that releases neurotransmitter into the blood upon depolarisation
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A cell that releases hormones across the synaptic cleft upon depolarisation
-
A cell that releases hormones onto neighbouring cells upon depolarisation
Pregunta 3
Pregunta
What type of chemical signalling occurs when a cell targets itself?
Respuesta
-
Autocrine
-
Paracrine
-
Endocrine
-
Neuroendocrine
Pregunta 4
Pregunta
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Respuesta
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Pregunta 5
Pregunta
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Respuesta
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Pregunta 6
Pregunta
Which of the following hormones are secreted by neurosecretory cells?
Pregunta 7
Pregunta
Which of the following hormones are secreted by epithelial tissues?
Pregunta 8
Pregunta
What gives a hormone a long half-life?
Pregunta 9
Pregunta
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Pregunta 10
Pregunta
How are active protein/peptide hormones released?
Pregunta 11
Pregunta
Are protein/peptide hormones protein-bound in circulation?
Pregunta 12
Pregunta
Which is true of protein hormones in circulation?
Respuesta
-
Long half-life
-
Short half-life
Pregunta 13
Pregunta
The following questions will be about steroid hormones. What are steroid hormones derived from?
Respuesta
-
Cholesterol
-
Proteins
-
Amines
-
DNA
Pregunta 14
Pregunta
Steroid hormones are lipid soluble.
Pregunta 15
Pregunta
Steroid hormones are stored in glands.
Pregunta 16
Pregunta
Are steroid hormones protein-bound in circulation?
Pregunta 17
Pregunta
Which is true of steroid hormones?
Respuesta
-
Long half-lives
-
Short half-lives
Pregunta 18
Pregunta
The following questions will be about amine hormones. Most amine hormones are derived from...?
Respuesta
-
Tyrosine
-
Phenylalanine
-
Glutamate
-
Aspartate
Pregunta 19
Pregunta
Thyroid hormones are amine hormones.
Pregunta 20
Pregunta
Which subtype of amine hormone is lipid-soluble?
Pregunta 21
Pregunta
Which subtype of amine hormone is water-soluble?
Pregunta 22
Pregunta
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Pregunta 23
Pregunta
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Pregunta 24
Pregunta
Which subtype of amine hormones are stored intracellulary in secretory granules?
Pregunta 25
Pregunta
What are eicosanoids?
Pregunta 26
Pregunta
What are eicosanoids derived from?
Respuesta
-
Arachidonic acid
-
Diacylglycerol
-
Inositol
-
PIP2
Pregunta 27
Pregunta
Which of the following is an example of an eicosanoid?
Respuesta
-
Prostaglandin
-
Catecholamine
-
Adrenaline
-
Parathyroid hormone
Pregunta 28
Pregunta
Which of the following hormones have intracellular receptors that alter gene transcription?
Pregunta 29
Pregunta
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Respuesta
-
Steroid hormones
-
Thyroid hormones
-
Protein/peptide hormones
-
Glycoproteins
-
Catecholamines
Pregunta 30
Pregunta
Drag and drop the correct answers to describe the mechanism of steroid hormones.
1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble.
2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end].
3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA.
4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA.
5. Binding alters [blank_start]transcription[blank_end] of target genes.
Pregunta 31
Pregunta
Which of the following can control hormone secretion?
Respuesta
-
Change in plasma ion concentration
-
Change in plasma nutrient concentration
-
Neurotransmitter release from neurones contacting endocrine cells
-
Upstream hormone/paracrine agents acting on endocrine cells
-
Conscious effort
-
Repetitive limb movement
-
Lipolysis
Pregunta 32
Pregunta
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Pregunta 33
Pregunta
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Pregunta 34
Pregunta
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Pregunta 35
Pregunta
Drag and drop the correct labels to describe the development of the pituitary gland.
Pregunta 36
Pregunta
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Pregunta 37
Pregunta
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis.
1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei.
2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells.
3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals.
4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Respuesta
-
cell bodies
-
hypothalamic
-
thalamic
-
cortical
-
axons
-
neuroendocrine
-
endocrine
-
paracrine
-
Herring bodies
-
pituicytes
-
venous blood
-
tissue fluid
-
surrounding CSF
Pregunta 38
Pregunta
What is the effect of ADH?
Respuesta
-
Increased water resorption in the kidney
-
Decreased water resorption in the kidney
-
Increase in uterine contractions
-
Stimulation of the adrenal glands
Pregunta 39
Pregunta
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Pregunta 40
Pregunta
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis.
1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones.
2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end].
3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end].
4. The hypothalamic hormones control release of anterior pituitary hormones.
Pregunta 41
Pregunta
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Pregunta 42
Pregunta
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Respuesta
-
Supraoptic nuclei
-
Paraventricular nuclei
-
Superior hypophyseal artery
-
Infundibulum
-
Inferior hypophyseal artery
-
trabecular artery
-
Hypophyseal veins
-
Endocrine cells
-
Anterior pituitary/adenohypophysis
-
Posterior pituitary/neurohypophysis
Pregunta 43
Pregunta
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Pregunta 44
Pregunta
What do the hypothalamic hypophysiotrophic hormones do?
Respuesta
-
Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
-
Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
-
Increase body temperature
-
Initiate reproductive behaviour
Pregunta 45
Pregunta
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Respuesta
-
Thyrotropin-releasing hormone
-
Dopamine
-
Corticotropin-releasing hormone
-
Gonadotrophin-releasing hormone
-
Growth-hormone releasing hormone
-
Somatostatin
-
Thyrotroph cells
-
Lactotroph cells
-
Corticotroph cells
-
Gonadotroph cells
-
Somatotroph cells
-
Thyroid-stimulating hormone
-
Prolactin
-
Adrenocorticotrophic hormone
-
Luteinising hormone
-
Follicle-stimulating hormone
-
Growth hormone