Transfusion Science Multiple Choice Questions

Descripción

Includes Kell, Kidd, Duffy, Lutheran, MNS, Lewis and more
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Resumen del Recurso

Pregunta 1

Pregunta
Which one of the following is NOT true about Kell system antibodies
Respuesta
  • Usually clinically significant IgG antibodies
  • Best detected in indirect antiglobulin tests
  • Fail to react in enzyme tests
  • Do not activate complement

Pregunta 2

Pregunta
Antibodies to the Kell, Kidd and Duffy systems all share the following traits except
Respuesta
  • Can cause haemolytic disease of the newborn and foetus
  • Enhanced with enzyme treatment
  • Can cause haemolytic transfusion reactions
  • usually detected only by indirect antiglobulin test

Pregunta 3

Pregunta
Which of the following phenotypes is heterozygous
Respuesta
  • Fy(a-b+)
  • Jk(a+b+)
  • Lu(a-b-)HIV
  • Jk(a-b+)

Pregunta 4

Pregunta
Which of the antibodies from the following blood group systems shows a dosage effect?
Respuesta
  • Lutheran
  • Kell
  • Duffy
  • P
  • Lewis

Pregunta 5

Pregunta
Antibodies to k antigen are not commonly detected in transfusion screening because
Respuesta
  • k antigen is of high incidence
  • the antibodies do not cause transfusion reactions
  • antibodies best react at 4 degree (C)
  • The antigen is of low incidence
  • k antigen is not present on screening cells

Pregunta 6

Pregunta
Lewis system antibodies have not been implicated in haemolytic disease of the new born and foetus because
Respuesta
  • the antigens are not fully developed at birth
  • Lewis system antibodies do not cross the placenta
  • the antibodies are not clinically significant
  • the antigens are primarily plasma based
  • All of the above

Pregunta 7

Pregunta
The Donath-Landsteiner antibody is
Respuesta
  • an IgG auto anti-P
  • an IgM auto anti-P
  • an IgM auto anti-I
  • anti-IH that reacts at cold temperatures

Pregunta 8

Pregunta
Which of the following cells has the highest concentration of M antigens
Respuesta
  • MNSs
  • MNs
  • NSs
  • MSs
  • NS

Pregunta 9

Pregunta
Which of the following does not result in an Lu(a-b-) phenotype
Respuesta
  • Deletion of the genes on the Lu locus
  • Amorphic genes of the Lu locus
  • Delayed anamestic heamolytic transfusion reaction
  • A suppressor gene on the X-chromosome
  • An inhibitor gene on another locus

Pregunta 10

Pregunta
The top and bottom pack comprises of
Respuesta
  • Single packs joined together
  • Triple pack
  • Double pack
  • Quadruple pack
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