biochem-1

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Pregunta 1

Pregunta
Process used in an expression vector to increase yield of recombinant protein synthesis ?
Respuesta
  • Translation initiation
  • Promoter induction
  • Transcription terminators
  • Multiple cloning sites

Pregunta 2

Pregunta
Rothera’s test is utilised for detection of?
Respuesta
  • Glucose
  • Proteins
  • Urea
  • Ketone bodies

Pregunta 3

Pregunta
Decreased energy production in thiamine deficiency is due to?
Respuesta
  • It is a cofactor for oxidative reduction
  • It is required for transamination reactions
  • It is a coenzyme for alpha ketoglutarate dehydrogenase and pyruvate dehydrogenase in citric acid cycle
  • It is a coenzyme for transketolase in hexose monophosphate shunt

Pregunta 4

Pregunta
Which of the following enzymes is responsible for the transfer of amino groups from an amino acid to an alpha keto acid?
Respuesta
  • Transaminase
  • Transketolase
  • Deaminase
  • Lyase

Pregunta 5

Pregunta
Site of urea cycle is?
Respuesta
  • Liver
  • Kidney
  • GIT
  • Lungs

Pregunta 6

Pregunta
Which of the following is not a protein misfolding disorder?
Respuesta
  • Tuberculosis
  • Creutzfeldt Jakob disease
  • Alzheimer’s disease
  • Cystic fibrosis

Pregunta 7

Pregunta
Sphingomyelinase deficiency is characteristic of ?
Respuesta
  • Fabry disease
  • Krabbe’s disease
  • Tay Sachs disease
  • Niemann Pick disease

Pregunta 8

Pregunta
Xeroderma pigmentosum is produced as a result of a defect in :
Respuesta
  • DNA polymerase III
  • DNA exonuclease
  • DNA ligase
  • none

Pregunta 9

Pregunta
A genetic disorder renders fructose 1,6 — biphosphatase in liver less sensitive to regulation by fructose 2,6 — bi-phosphate. All of the following metabolic changes are observed in this disorder except:
Respuesta
  • Level of fructose 1,6—biphosphate is higher than normal
  • Level of fructose 1,6 — biphosphate is lower than normal
  • Less pyruvate is formed
  • Less ATP is generated

Pregunta 10

Pregunta
Alpha helix and Beta pleated sheet are examples of:
Respuesta
  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure
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