34379550
Descripción
Test por ACAPUN INSTITUTE, actualizado hace más de 1 año
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Creado por ACAPUN INSTITUTE
hace casi 3 años
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Pregunta 1
Pregunta
Atropine and propantheline exert their effects on peripheral structures by
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a. preventing release of acetylcholine
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b. preventing synthesis of acetylcholine
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c. enhancing destruction of acetylcholine
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d. competeing with acetylcholine for receptor sites
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e. producing physiologic effects opposite to those of acetylcholine
Pregunta 2
Pregunta
Neostigmine produces its effect by physostigmine. These differ from the insecticides and nerve gases listed below in that they are reversible and can be used clinically; the latter are irreversible
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a. depressing acetylcholinesterase release
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b. inhibiting acetylcholinesterase activity
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c. increasing the rate of acetylcholine synthesis
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d. acting like acetylcholine at ganglionic sites
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e. increasing the amount of acetylcholine released from nerve terminals
Pregunta 3
Pregunta
Organophosphate insecticides and nerve gases inhibit the action of which of the following enzymes?
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a. adenylate cyclase
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b. monoamine oxidase
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c. phosphodiesterase
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d. acetylcholinesterase
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e. carbonic anhydrase
Pregunta 4
Pregunta
Drugs which are additive with or potentiate the effects of acetylcholine include
(a) methacholine
(b) scopolamine
(c) pralidoxime
(d) neostigmine
(e) pilocarpine
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1. (a), (b), and (c)
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2. (a), (c), and (d)
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3. (a), (d) and (e)
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4. (b), (d), and (e)
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5. (c), (d) and (e)
Pregunta 5
Pregunta
Which of the following drugs is best to administer after poisoning by an organophosphate cholinesterase inhibitor?
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a. atropine
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b. phenytoin
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c. pralidoxime
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d. propantheline
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e. phenobarbital
Pregunta 6
Pregunta
Which of the following compounds is a ganglionic blocking agent?
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a. curarine
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b. edrophonium
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c. mecamylamine
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d. succinylcholine
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e. gallamine triethodide
Pregunta 7
Pregunta
Which of the following acts by antagonizing cholinesterase?
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a. atropine
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b. muscarine
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c. neostigmine
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d. pilocarpine
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e. acetylcholine
Pregunta 8
Pregunta
When neostigmine is administered before acetylcholine, the action of acetylcholine will be
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a. blocked
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b. enhanced and prolonged
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c. less intense and of shorter duration
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d. none of the above. The action of acetylcholine is not affected by neostigmine
Pregunta 9
Pregunta
Neostigmine can stimulate denervated skeletal muscle because it
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a. is a congener of acetylcholine
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b. is a competitive blocking agent
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c. has no effect on acetylcholinesterase
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d. is more potent than diisopropylfluorophosphate
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e. is capable of acting directly on the end-plate
Pregunta 10
Pregunta
Which of the following is used to prevent laryngospasm?
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a. atropine
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b. epinephrine
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c. diazepam (Valium)
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d. neostigmine (Prostigmine)
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e. succinylcholine (Anectine)
Pregunta 11
Pregunta
In treating xerostomia, which of the following might be prescribed?
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a. atropine
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b. ephedrine
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c. neostigmine
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d. scopolamine
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e. mecamylamine
Pregunta 12
Pregunta
Which of the following drugs is most likely to dry secretions in the oral cavity?
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a. diazepam
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b. promethazine
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c. physostigmine
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d. propantheline
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e. diphenhydramine
Pregunta 13
Pregunta
The most useful drug to induce salivation is one which has properties that are
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a. adrenergic
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b. cholinergic
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c. ganglionic blocking
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d. adrenergic blocking
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e. cholinergic blocking
Pregunta 14
Pregunta
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Pregunta 15
Pregunta
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Pregunta 16
Pregunta
Tachycardia in a patient administered with atropine or scopolamine results from
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a. release of adrenal catecholamines
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b. blockade of vagus nerve activity
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c. blockade of the nicotinic cholinergic receptor
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d. stimulation of the alpha adrenergic receptor
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e. stimulation of the beta adrenergic receptor
Pregunta 17
Pregunta
All of the following are possible effects of cholinomimetic drugs except
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a. mydriasis
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b. bradycardia
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c. increased peristalsis
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d. stimulation of sweat glands
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e. increased secretion by bronchial glands
Pregunta 18
Pregunta
A paralyzing dose of succinylcholine initially elicits
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a. CNS stimulation
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b. CNS depression
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c. decreased salivation
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d. muscle fasiculation
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e. extrapyramidal reactions
Pregunta 19
Pregunta
Based on its known mechanism and sites of action, scopolamine should theoretically be useful in
(a) treatment of peptic ulcer
(b) providing euphoria and amnesia prior to surgery
(c) relieving bronchoconstriction
(d) relieving some of the symptoms of Parkinson disease
(e) visualization of the retina
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1. (a), (b), (d) and (e)
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2. (a), (b), and (e) only
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3. (a),and (c)
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4. (b) and (e) only
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5. All of the above
Pregunta 20
Pregunta
Symptoms of poisoning by an organophosphate insecticide include all of the following except:
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a. skeletal muscle fasiculation
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b. excessive salivation
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c. bronchoconstriction
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d. hot, dry skin
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e. diarrhea
Pregunta 21
Pregunta
All of the following symptoms are associated with neostigmine poisoning except
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a. diarrhea
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b. salivation
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c. convulsions
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d. bonchiolar constriction
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e. skeletal muscle paralysis
Pregunta 22
Pregunta
Symptoms of atropine poisoning in man include
(a) decreased intraocular pressure
(b) burning dry mouth
(c) nausea, vomiting and diarrhea
(d) hyperthermia
(e) orthostatic hypotension
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1. (a) and (c)
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2. (b) and (d)
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3. (b), (d), and (e)
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4. (d) and (e)
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5. All of the above
Pregunta 23
Pregunta
The most likely signs or symptoms of overdosage with atropine are
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a. CNS excitation and tachycardia
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b. intestinal cramps and diarrhea
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d. ptyalism and increased sweating
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e. constriction of the pupils and blurring of vision
Pregunta 24
Pregunta
Disorientation, confusion and hallucinations resulting from an overdose of scopolamine are most efficaciuosly treated by administering
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a. atropine
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b. levodopa
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c. acetylcholine
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d. physostigmine
Pregunta 25
Pregunta
The immediate cause of death from irreversible cholinesterase inhibitors is
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a. shock
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b. convulsion
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c. cardiac arrhythmia
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d. respiratory paralysis
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e. dehydration from vomiting and diarrhea
Pregunta 26
Pregunta
Each of the following is a symptom of cholinergic crisis except
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a. bradycardia
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b. lacrimation
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c. vasoconstriction
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d. extreme salivation
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e. weakness of voluntary muscles
Pregunta 27
Pregunta
Succinylcholine is a short-acting neuromuscular junction blocking agent useful for providing a brief paralysis to aid in intubating patients. It is short-acting because
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a. it is subject to rapid metabolism in the liver
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b. it rapidly redistributes away from the NMJ
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c. it is subject to inactivation by plasma esterases
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d. it undergoes rapid inactivation in the GI tract
Pregunta 28
Pregunta
Atropine-like drugs are classed as
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a. anti-adrenergic
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b. cholinomimetic
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c. sympatholytic
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d. anti-cholinergic
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e. sympathomimetic
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