Pregunta 1
Pregunta
Which of the following are pharmacologic properties of antipsychotic drugs?
a. They block the dopamine receptor
b. They affect the hypothalamic temperature regulation system
c. They cause emesis
d. They are synergistic with LSD
e. They cause hypertension
Respuesta
-
a) (a) and (b) only
-
b) (a), (b) and (c)
-
c) (b), (c) and (d)
-
d) (c), (d) and (e)
-
e) (d) and (e) only
Pregunta 2
Pregunta
The antipsychotic effects of the phenothiazines are probably the result of
Respuesta
-
a. Release of serotonin in the brain
-
b. Release of norepinephrine in the brain
-
c. Blockade of dopaminergic sites in the brain
-
d. Prevention of the release of norepinephrine from brain neuron terminals
-
e. Increase in the dopamine content of the cerebral cortex
Pregunta 3
Pregunta
The antipsychotic effects of phenothiazines result from
Respuesta
-
a. Release of serotonin in the brain
-
b. Release of norepinephrine in the brain
-
c. Blockade of dopaminergic sites in the brain
-
d. An increase in the dopamine content of the cerebral cortex
-
e. Prevention of the release of norepinephrine from brain neuron terminals
Pregunta 4
Pregunta
Chlorpromazine and related drugs are thought at act by blocking which of the following receptors?
Respuesta
-
a. Adrenergic
-
b. Muscarinic
-
c. Dopaminergic
-
d. Central serotonin
Pregunta 5
Pregunta
Which of the following is an irreversible side-effect resulting from longterm administration of phenothiazines?
Respuesta
-
a. Sedation
-
b. Xerostomia
-
c. Infertility
-
d. Parkinsonism
-
e. Tardive dyskinesia
Pregunta 6
Pregunta
Tardive dyskinesia is a neurological side-effect of which of the following classes of drugs?
Respuesta
-
a. Alcohols
-
b. Tricyclic antidepressants
-
c. Barbiturate antiepileptics
-
d. Phenothiazine antipsychotics
-
e. Monoamine oxidase inhibitors
Pregunta 7
Pregunta
Which of the following drugs are most likely to cause extrapyramidal\ stimulation?
Respuesta
-
a. Antibiotics
-
b. Salicylates
-
c. Barbiturates
-
d. Phenothiazines
-
e. Benzodiazepines
Pregunta 8
Pregunta
Phenothiazine derivatives do NOT produce
Pregunta 9
Pregunta
All of the following actions are associated with the use of chlorpromazine EXCEPT:
Pregunta 10
Pregunta
The drug most commonly used to treat severe mental depression is
Respuesta
-
a. Sodium
-
b. Imipramine
-
c. Chlorpromazine
-
d. Tranylcypromine
-
e. Dextroamphetamine
Pregunta 11
Pregunta
Which of the following drugs is most effective as an antidepressant?
Respuesta
-
a. Diazepam
-
b. Reserpine
-
c. Amitriptyline
-
d. Chlorpromazine
-
e. Hydroxyzine
Pregunta 12
Pregunta
Which of the following is most likely to be the major mechanism of action of the tricyclic antidepressants?
Respuesta
-
a. Enhanced release of acetylcholine
-
b. Inhibition of neuronal synthesis of norepinephrine
-
c. Potentiation of serotonin synthesis in nervous tissue
-
d. Stimulation of reuptake of norepinephrine from the synaptic cleft
-
e. Blockade of the reuptake of amine neurotransmitters released into the synaptic cleft
Pregunta 13
Pregunta
Tricyclic antidepressants have a prominent side effect that most nearly resembles the usual pharmacological action of
Respuesta
-
a. Codeine
-
b. Atropine
-
c. Ephedrine
-
d. Propranolol
-
e. Methacholine
Pregunta 14
Pregunta
Which of the following drugs has its primary use in the treatment of the manic phase of depressive psychosis?
Respuesta
-
a. Lithium
-
b. Reserpine
-
c. Imipramine
-
d. Amphetamine
-
e. Chlorpromazine
Pregunta 15
Pregunta
Which of the following are pharmacologic properties of antipsychotic drugs?
a. They block the dopamine receptor
b. They affect the hypothalamic temperature regulation system
c. They cause emesis
d. They are synergistic with LSD
e. They cause hypertension
Respuesta
-
a) (a) and (b) only
-
b) (a), (b) and (c)
-
c) (b), (c) and (d)
-
d) (c), (d) and (e)
-
e) (d) and (e) only
Pregunta 16
Pregunta
The antipsychotic effects of the phenothiazines are probably the result of
Respuesta
-
a. Release of serotonin in the brain
-
b. Release of norepinephrine in the brain
-
c. Blockade of dopaminergic sites in the brain
-
d. Prevention of the release of norepinephrine from brain neuron terminals
-
e. Increase in the dopamine content of the cerebral cortex
Pregunta 17
Pregunta
The antipsychotic effects of phenothiazines result from
Respuesta
-
a. Release of serotonin in the brain
-
b. Release of norepinephrine in the brain
-
c. Blockade of dopaminergic sites in the brain
-
d. An increase in the dopamine content of the cerebral cortex
-
e. Prevention of the release of norepinephrine from brain neuron terminals
Pregunta 18
Pregunta
Chlorpromazine and related drugs are thought at act by blocking which of the following receptors?
Respuesta
-
a. Adrenergic
-
b. Muscarinic
-
c. Dopaminergic
-
d. Central serotonin
Pregunta 19
Pregunta
Which of the following is an irreversible side-effect resulting from longterm administration of phenothiazines?
Respuesta
-
a. Sedation
-
b. Xerostomia
-
c. Infertility
-
d. Parkinsonism
-
e. Tardive dyskinesia
Pregunta 20
Pregunta
Tardive dyskinesia is a neurological side-effect of which of the following classes of drugs?
Respuesta
-
a. Alcohols
-
b. Tricyclic antidepressants
-
c. Barbiturate antiepileptics
-
d. Phenothiazine antipsychotics
-
e. Monoamine oxidase inhibitors
Pregunta 21
Pregunta
Which of the following drugs are most likely to cause extrapyramidal\ stimulation?
Respuesta
-
a. Antibiotics
-
b. Salicylates
-
c. Barbiturates
-
d. Phenothiazines
-
e. Benzodiazepines
Pregunta 22
Pregunta
Phenothiazine derivatives do NOT produce
Pregunta 23
Pregunta
All of the following actions are associated with the use of chlorpromazine EXCEPT:
Pregunta 24
Pregunta
The drug most commonly used to treat severe mental depression is
Respuesta
-
a. Sodium
-
b. Imipramine
-
c. Chlorpromazine
-
d. Tranylcypromine
-
e. Dextroamphetamine
Pregunta 25
Pregunta
Which of the following drugs is most effective as an antidepressant?
Respuesta
-
a. Diazepam
-
b. Reserpine
-
c. Amitriptyline
-
d. Chlorpromazine
-
e. Hydroxyzine
Pregunta 26
Pregunta
Which of the following is most likely to be the major mechanism of action of the tricyclic antidepressants?
Respuesta
-
a. Enhanced release of acetylcholine
-
b. Inhibition of neuronal synthesis of norepinephrine
-
c. Potentiation of serotonin synthesis in nervous tissue
-
d. Stimulation of reuptake of norepinephrine from the synaptic cleft
-
e. Blockade of the reuptake of amine neurotransmitters released into the synaptic cleft
Pregunta 27
Pregunta
Tricyclic antidepressants have a prominent side effect that most nearly resembles the usual pharmacological action of
Respuesta
-
a. Codeine
-
b. Atropine
-
c. Ephedrine
-
d. Propranolol
-
e. Methacholine
Pregunta 28
Pregunta
Which of the following drugs has its primary use in the treatment of the manic phase of depressive psychosis?
Respuesta
-
a. Lithium
-
b. Reserpine
-
c. Imipramine
-
d. Amphetamine
-
e. Chlorpromazine
Pregunta 29
Pregunta
Lithium carbonate is particularly effective in treating
Pregunta 30
Pregunta
The current drug of choice for treatment of the manic phase of manic-depressive psychosis is
Respuesta
-
a. Lithium
-
b. Caffeine
-
c. Reserpine
-
d. Imipramine
-
e. Amphetamine