35292037
Descripción
Test por Esmeralda Espitia, actualizado hace más de 1 año
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Creado por Esmeralda Espitia
hace casi 3 años
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Pregunta 1
Pregunta
1. What genetic process is likely responsible for the occurrence of asthma in only one of a pair of identical twins?
Respuesta
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a. Epigenetic modifications
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b. Genomic imprinting
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c. Transgenerational inheritance
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d. Methylation
Pregunta 2
Pregunta
2. Prader-Willi syndrome causes a chromosomal defect that is what?
Respuesta
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a. Initiated by postnatal exposure to a virus
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b. Inherited from the father
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c. Related to maternal alcohol abuse
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d. Transferred from mother to child
Pregunta 3
Pregunta
3. What can a malfunction in DNA methylation lead to?
Respuesta
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a. Hypothyroidism
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b. Blindness
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c. Cancer
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d. Diabetes mellitus
Pregunta 4
Pregunta
4. Which statement is true regarding the embryonic development of stem cells?
Respuesta
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a. They are already differentiated.
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b. They are referred to as housekeeping genes.
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c. They already demonstrate DNA sequencing.
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d. They are said to be totipotent.
Pregunta 5
Pregunta
5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are over- expressed. What would be the resulting effect on existing cancer?
Respuesta
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a. Cell death
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b. Metastasis
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c. Remission
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d. Relapse
Pregunta 6
Pregunta
6. What is the difference between DNA sequence mutations and epigenetic modifications?
Respuesta
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a. DNA sequence mutations can be directly altered.
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b. Leukemia is a result of only DNA sequence mutation.
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c. Epigenetic modifications potentially can be reversed.
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d. No known drug therapies are available for epigenetic modifications.
Pregunta 7
Pregunta
7. Which term refers to the silenced gene of a gene pair?
Respuesta
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a. Activated
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b. Altered
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c. Mutated
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d. Imprinted
Pregunta 8
Pregunta
8. What is most likely the shape of the face of a child diagnosed with Russell-Silver syndrome?
Respuesta
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a. Round
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b. Square
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c. Triangular
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d. Elongated
Pregunta 9
Pregunta
9. What are genes responsible for the maintenance of all cells referred to as?
Respuesta
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a. Universal
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b. Managerial
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c. Housekeeping
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d. Executive
Pregunta 10
Pregunta
10. What is the belief regarding twins who adopt dramatically different lifestyles?
Respuesta
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a. They may experience very different aging processes.
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b. They will retain very similar methylation patterns.
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c. They will experience identical phenotypes throughout their lifespans.
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d. They may never demonstrate similar DNA sequences of their somatic cells.
Pregunta 11
Pregunta
11. What do hypomethylation and the resulting effect on oncogenes result in?
Respuesta
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a. A decrease in the activity of the oncogene, thus suppressing cancer development.
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b. A deactivation of MLH1 to halt DNA repair.
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c. An increase in tumor progression from benign to malignant.
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d. An over-expression of microRNA, resulting in tumorigenesis.
Pregunta 12
Pregunta
12. When a chromosome lacking 4 million base pairs is inherited from the mother, the child is at risk for developing which syndrome?
Respuesta
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a. Prader-Willi
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b. Angelman
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c. Beckwith-Wiedemann
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d. Russell-Silver
Pregunta 13
Pregunta
2. A diagnosis of Angelman syndrome in a child is supported by which assessment findings?(Select all that apply.)
Respuesta
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a. Small feet and hands
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b. Profound intellectual disability
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c. Obesity
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d. Ataxic gait
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e. History of seizures
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