Ch. 6 Epigentics

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patho 1 Test sobre Ch. 6 Epigentics, creado por Esmeralda Espitia el 04/02/2022.
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Resumen del Recurso

Pregunta 1

Pregunta
1. What genetic process is likely responsible for the occurrence of asthma in only one of a pair of identical twins?
Respuesta
  • a. Epigenetic modifications
  • b. Genomic imprinting
  • c. Transgenerational inheritance
  • d. Methylation

Pregunta 2

Pregunta
2. Prader-Willi syndrome causes a chromosomal defect that is what?
Respuesta
  • a. Initiated by postnatal exposure to a virus
  • b. Inherited from the father
  • c. Related to maternal alcohol abuse
  • d. Transferred from mother to child

Pregunta 3

Pregunta
3. What can a malfunction in DNA methylation lead to?
Respuesta
  • a. Hypothyroidism
  • b. Blindness
  • c. Cancer
  • d. Diabetes mellitus

Pregunta 4

Pregunta
4. Which statement is true regarding the embryonic development of stem cells?
Respuesta
  • a. They are already differentiated.
  • b. They are referred to as housekeeping genes.
  • c. They already demonstrate DNA sequencing.
  • d. They are said to be totipotent.

Pregunta 5

Pregunta
5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are over- expressed. What would be the resulting effect on existing cancer?
Respuesta
  • a. Cell death
  • b. Metastasis
  • c. Remission
  • d. Relapse

Pregunta 6

Pregunta
6. What is the difference between DNA sequence mutations and epigenetic modifications?
Respuesta
  • a. DNA sequence mutations can be directly altered.
  • b. Leukemia is a result of only DNA sequence mutation.
  • c. Epigenetic modifications potentially can be reversed.
  • d. No known drug therapies are available for epigenetic modifications.

Pregunta 7

Pregunta
7. Which term refers to the silenced gene of a gene pair?
Respuesta
  • a. Activated
  • b. Altered
  • c. Mutated
  • d. Imprinted

Pregunta 8

Pregunta
8. What is most likely the shape of the face of a child diagnosed with Russell-Silver syndrome?
Respuesta
  • a. Round
  • b. Square
  • c. Triangular
  • d. Elongated

Pregunta 9

Pregunta
9. What are genes responsible for the maintenance of all cells referred to as?
Respuesta
  • a. Universal
  • b. Managerial
  • c. Housekeeping
  • d. Executive

Pregunta 10

Pregunta
10. What is the belief regarding twins who adopt dramatically different lifestyles?
Respuesta
  • a. They may experience very different aging processes.
  • b. They will retain very similar methylation patterns.
  • c. They will experience identical phenotypes throughout their lifespans.
  • d. They may never demonstrate similar DNA sequences of their somatic cells.

Pregunta 11

Pregunta
11. What do hypomethylation and the resulting effect on oncogenes result in?
Respuesta
  • a. A decrease in the activity of the oncogene, thus suppressing cancer development.
  • b. A deactivation of MLH1 to halt DNA repair.
  • c. An increase in tumor progression from benign to malignant.
  • d. An over-expression of microRNA, resulting in tumorigenesis.

Pregunta 12

Pregunta
12. When a chromosome lacking 4 million base pairs is inherited from the mother, the child is at risk for developing which syndrome?
Respuesta
  • a. Prader-Willi
  • b. Angelman
  • c. Beckwith-Wiedemann
  • d. Russell-Silver

Pregunta 13

Pregunta
2. A diagnosis of Angelman syndrome in a child is supported by which assessment findings?(Select all that apply.)
Respuesta
  • a. Small feet and hands
  • b. Profound intellectual disability
  • c. Obesity
  • d. Ataxic gait
  • e. History of seizures
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