Melatonin is produced by which of the following pathways.
Substances:
1.Serotonin
2.Melatonin
3.L-Tryptophan
4.N-Acetyl Serotonin
5.5-HTP
Enzymes:
A.tryptophan 5-hydroxylase
B.acetylserotonin O-methyltransferase
C.AANAT
D.5-HTP decarboxylase
Respuesta
1B4D2A3C5
3A5D1C4B2
3A1C5D4B2
1B4D3C2A5
Pregunta 3
Pregunta
Bioavailability and Half-Life of Melatonin
Respuesta
30-50% and 30-50 Minutes.
40-60% and 20 to 30 Minutes.
15-25% and 60 to 90 Minutes.
60-80% and 90 to 120 Minutes.
Pregunta 4
Pregunta
Melatonin is regulated by Norepinephrine by which pathway:
Substance:
1.Norepinephrine
Enzyme:
A.PKA
B.AANAT
Receptor:
a.Beta Adrenergic
Respuesta
1aBA
Ba1A
AB1a
1aAB
Pregunta 5
Pregunta
Light of which of the following wavelength criteria will not inhibit melatonin
Respuesta
Under 530 nm.
Over 480 nm.
Over 530 nm.
Under 480 nm.
Pregunta 6
Pregunta
Dopamine plays a role in Melatonin secretion by:
Respuesta
Providing negative feedback to Melatonin formation.
Upregulating Melatonin receptors.
Enhancing the effects of Norepinephrine on Melatonin secretion.
Increasing in response to Melatonin binding with receptors.
Pregunta 7
Pregunta
5HT has which of the following functions and changes:
Respuesta
It decreases Serotonin production.
It is decreased by AANAT to be converted to Melatonin.
It is produced only during the day.
Its production leads to increased sympathetic activity and receptor activation on the pineal gland, ultimately leading to decreased Melatonin synthesis.
Dopamine activation of the D4 receptor heteromeres decreases 5HT in the morning.
Pregunta 8
Pregunta
The Pineal Gland is located outside of the blood brain barrier.