Pregunta 1
Pregunta
In normal RBC destruction, globin is recycled and Fe is broken down
Pregunta 2
Pregunta
In Intravascular Haemolytic Anaemia, cells are lysed in the blood vessels
Pregunta 3
Pregunta
Why is Intravascular H.A so dangerous?
Respuesta
-
Hb dimers form in the blood and block the kidneys
-
R.B.C fragments block capillaries
-
R.B.C's aggregate and block capillaries
Pregunta 4
Pregunta
Renal failure and Heamoglobinurea are caused by...
Respuesta
-
Intravascular
-
Extravascular
Pregunta 5
Pregunta
What is implicated in Extravascular Haemolytic Anaemia
Respuesta
-
The spleen
-
The bone marrow
-
The liver
Pregunta 6
Pregunta
In Extravascular, macrophage Fc receptors bind to the RBC's Ig's
Pregunta 7
Pregunta
Once bound, what happens to RBC's in Haemolytic Anaemia
Pregunta 8
Pregunta
If small portions of RBC membrane is removed, what happens?
Pregunta 9
Pregunta
Loss of RBC's leads to low glucose in the spleen, which leads to...
Respuesta
-
Inc haemolysis
-
Fatigue
-
Inc risk of diabetes
Pregunta 10
Pregunta
Reticuloctosis- inc presence of reticulocytes
Pregunta 11
Pregunta
What causes reticulocytosis?
Respuesta
-
The body trying to replace lost R.B.C's but can't keep up production
-
The damaged R.B.Cs degenerate into reticulocytes
-
The lymphocytes attack R.B.Cs, making them degenerate into reticulocytes
Pregunta 12
Pregunta
In Drug Induced Haemolytic Anaemia, what happens?
Respuesta
-
Drug induced antibodies cross react
-
Drug specific antibodies cross react
-
Drugs cause R.B.C's to aggregate
Pregunta 13
Pregunta
Haemolytic Anaemias can be caused by physical stress....
Pregunta 14
Pregunta
March Haemoglobinurea is damge to RBC's in small foot bones due to prolonged marching/running
Pregunta 15
Pregunta
Infections can cause H.A by altering R.B.C morphology
Pregunta 16
Pregunta
What's the difference between Immune and Autoimmune Haemolytic Anaemia?
Pregunta 17
Pregunta
In some cases, an RBC transfusion can lead to degredation of the original RBC's
Pregunta 18
Pregunta
Name two types of Inherited Haemolytic Anaemia
Respuesta
-
Sickel Cell Anaemia
-
Thalassaemia
Pregunta 19
Pregunta
Hereditary Spherocytosis is caused by an abnormal membrane causing Spherical R.B.C's