Biophysics MCQs Part 2 PMU- 1st YR/2nd Sem

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Biophysics mcqs from pics
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Resumen del Recurso

Pregunta 1

Pregunta
Membrane potential operated channels are
Respuesta
  • active at fixed value of the membrane potential only
  • permanently active
  • active in certain range of membrane potential

Pregunta 2

Pregunta
Striated muscle are structure bases of
Respuesta
  • upper levels of gastro intestial
  • lower levels of gastro intestial
  • none of these

Pregunta 3

Pregunta
Muscle extraction is possible when
Respuesta
  • Ca ions are bounded
  • Ca contraction increase to 10^-5 mol/s
  • Ca to 10 millimols

Pregunta 4

Pregunta
Action potential is shape depends on
Respuesta
  • Irritation strength
  • Cell type
  • Amount of lipids in the membrane irritated

Pregunta 5

Pregunta
Action potential is
Respuesta
  • Minimal value of resting potential
  • Maximum value of resting potential
  • None of these

Pregunta 6

Pregunta
Elevation of calcium concentration is for
Respuesta
  • contraction
  • interruption of action potential
  • relaxion

Pregunta 7

Pregunta
Stable membrane is
Respuesta
  • phasic sm
  • tonic sm
  • both

Pregunta 8

Pregunta
Average power of contraction of smooth muscle per unit cross section
Respuesta
  • is smaller than that of striated muscle
  • bilayer
  • equal

Pregunta 9

Pregunta
Actin and myosin are in [blank_start]cellular fiber network[blank_end]
Respuesta
  • cellular fiber network

Pregunta 10

Pregunta
Smooth muscle cells are organised in [blank_start]bundles[blank_end] in strong parallel layers or spherical structures
Respuesta
  • bundles

Pregunta 11

Pregunta
Ion channels are
Respuesta
  • tubular links between cells
  • ionized groove upon the membrane
  • protein structures in membranes through which ions pass

Pregunta 12

Pregunta
Ion channels conductivity during the action potential
Respuesta
  • has a constant value
  • depends on the level of membrane potential
  • increases logarithimacally over the time

Pregunta 13

Pregunta
On the border water-air (the free surface of the water) lipids from
Respuesta
  • monolayer
  • three-layered electrically conductive structure
  • lipid gel

Pregunta 14

Pregunta
In stationary state the membrane potential
Respuesta
  • stays constant if parameters of the system are stable
  • is altered in sinus manner
  • slowly reaches to zero

Pregunta 15

Pregunta
Both smooth muscle contractions and skeletal muscle contractions involve thin (actin) filament over the thick (myosin) filaments
Respuesta
  • True
  • False

Pregunta 16

Pregunta
In smooth muscle contraction, the majority of calcium (Ca2+) needed for contraction enters from extracellular fluid.
Respuesta
  • True
  • False

Pregunta 17

Pregunta
Troponin and tropomyosin are attached to thick filaments of smooth muscle cells
Respuesta
  • True
  • False

Pregunta 18

Pregunta
Myosin of the thick filaments of smooth muscle cells must be phosphorylated in order to bind of the thin filaments
Respuesta
  • True
  • False

Pregunta 19

Pregunta
Nor-epinephrine released from sympathetic nerve terminals in the heart cause a decrease in the pacemaker activity.
Respuesta
  • True
  • False

Pregunta 20

Pregunta
The rapid upstoke (phase 0) of actin potentials in ventricular and atrial myocytes results from opening of Ca2+ channels.
Respuesta
  • True
  • False

Pregunta 21

Pregunta
Thick filaments are composed of myosin and thin filaments are primarily composed of actin.
Respuesta
  • True
  • False

Pregunta 22

Pregunta
Tropomyosin binds Ca2+ causing a conformational change that causes troponin to uncover binding sites on actin for crossbridge attachment.
Respuesta
  • True
  • False

Pregunta 23

Pregunta
Nifedine is a
Respuesta
  • Calcium (Ca2+) channel blocker
  • Sodium (Na+) channel blocker
  • Potassium (K+) channel blocker

Pregunta 24

Pregunta
Tetraethylammonium is a blocker for which channel?
Respuesta
  • Calcium (Ca2+) channel
  • Sodium (Na+) channel
  • Potassium (K+) channel

Pregunta 25

Pregunta
Verapamil is a
Respuesta
  • Calcium (Ca2+) channel blocker
  • Sodium (Na+) channel blocker
  • Potassium (K+) channel blocker

Pregunta 26

Pregunta
Which is not a type/class of carrier protein?
Respuesta
  • Uniport
  • Symport
  • Antiport
  • Microport

Pregunta 27

Pregunta
Ionophores have following action except
Respuesta
  • Inhibit ADP to ATP conversion
  • Abolish proton gradient
  • Abolish pH gradient
  • Hydrophilic in character

Pregunta 28

Pregunta
Diffusion through a semi-permeable membrane with different permeabilities for different substance is called:
Respuesta
  • Tran-Diffusion
  • Filtration
  • Osmosis
  • Diffusion

Pregunta 29

Pregunta
The pressure that would have to be applied to a pure solvent to prevent it from passing into a given solution by osmosis
Respuesta
  • Osmotic Pressure
  • Filtration Pressure
  • Osmotic Stability

Pregunta 30

Pregunta
Movement of liquid across a semipermeable membrane under hydrostatic pressure is called
Respuesta
  • Filtration
  • Hydrostatic Diffusion
  • Osmosis
  • None of these

Pregunta 31

Pregunta
GLUT1 and Ionophores valiomycin are examples of
Respuesta
  • Uniport
  • Symport
  • Antiport

Pregunta 32

Pregunta
Antiport is best described by
Respuesta
  • Carrier protein binds one solutes and transports it across the membrane
  • Carrier protein binds two different solutes and transport them together across the membrane
  • A substrate binds and is transported across the membrane then another substrate binds and is transported in the other direction

Pregunta 33

Pregunta
A factors that does NOT affect rate of facilitated diffusion:
Respuesta
  • Concentration gradient across the membrane
  • Amount of carrier proteins available
  • Speed of carrier and substrate attachment
  • How fast the protein changes shape after attachment
  • Mean Molecular Velocity

Pregunta 34

Pregunta
Which of these is not a type of ion channel?
Respuesta
  • Receptor Regulated
  • Membrane Potential-Dependent
  • Ion Regulated

Pregunta 35

Pregunta
Which of this is not a class of ATPase
Respuesta
  • P-Type
  • F-Type
  • V-Type
  • L-Type

Pregunta 36

Pregunta
Which statement is incorrect?
Respuesta
  • P-type- transport Na+, K+, Ca2+ through plasma membrane and in doing so they are phosphorylated
  • F-type- found in mitochondria where they are the prime producers of ATP by using the proton gradient generated by oxidative phosphorylation
  • V-type- only found in plant cells, catalysing ATP hydrolysis to transport solutes

Pregunta 37

Pregunta
The downhill (along concentration Gradient) movement of one species driving the uphill (against concentration Gradient) movement of another where metabolic energy is not utilised directly is called
Respuesta
  • Primary Active Transport
  • Secondary Active Transport
  • None of these

Pregunta 38

Pregunta
Which part of the sodium-potassium pump (Na=/K+ ATPase) has an ATP binding site and 3 other sites which have a high affinity for Na+ ion
Respuesta
  • the part of the protein that faces the cytoplasm (inner part)
  • the part of the protein that faces extracellular environment (outer part)
  • Both of these

Pregunta 39

Respuesta
  • Resting Potential
  • Depolarization
  • Repolarization
  • Hyperpolarization

Pregunta 40

Pregunta
The resting potential can be changed by chemical, mechanical or electrical stimulus
Respuesta
  • True
  • False

Pregunta 41

Pregunta
No refractory period is associated with graded potentials.
Respuesta
  • True
  • False

Pregunta 42

Pregunta
Quiescent cells
Respuesta
  • refer to the period when a cell is not dividing
  • refer to the period when a cell is dividing
  • none of these

Pregunta 43

Pregunta
If the membrane potential is changed slowly, the electrical current can pass without action potential needing to be initiated. This phenomena is known as
Respuesta
  • Accommodation
  • Action Potential
  • Electronic Potential
  • None of these

Pregunta 44

Pregunta
Fill in the gaps: (symbols like K+ /Na+/Ca2+ are used instead of word) Phase 0: Rapid depolarization: [blank_start]increased[blank_end] Na+ and [blank_start]decreased[blank_end] K+ conductances Phase 1: Initial re polarization: decreased [blank_start]Na+[blank_end] and increased [blank_start]K+[blank_end] conductances Phase 2: [blank_start]Plateau phase[blank_end]: increased [blank_start]Ca2+[blank_end] conductance Phase 3: Re-polarization: increased [blank_start]K+[blank_end] and decreased [blank_start]Ca2+[blank_end] conductances Phase 4:[blank_start]Resting potential[blank_end]: [blank_start]increased[blank_end] [blank_start]K+[blank_end] and [blank_start]decreased[blank_end] Na+ and [blank_start]decreased[blank_end] Ca2+ conductance
Respuesta
  • increased
  • decreased
  • Plateau phase
  • Na+
  • K+
  • Ca2+
  • K+
  • decreased
  • Resting potential
  • increased
  • decreased
  • K+
  • Ca2+

Pregunta 45

Pregunta
What results in a decrease of AP amplitude and depolarization block therefore the heart stops in diastole?
Respuesta
  • Increased sodium (Na+) extracellularly
  • Increased Potassium (K+) extracellularly
  • Decreased Potassium (K+) extracellularly

Pregunta 46

Pregunta
What results in shortening of the refractory period therefore a defibrilation risk?
Respuesta
  • Increased extracellular potassium (K+)
  • Decreased extracellular potassium (K+)
  • Increased extracellular calcium (Ca+)

Pregunta 47

Pregunta
What would cause a sudden decrease of AP depolarization phase and its duration resulting in cells becoming unexcitable?
Respuesta
  • Increased extracellular potassium (K+)
  • Increased extracellular sodium (Na+)
  • Decreased extracellular sodium (Na+)

Pregunta 48

Pregunta
Which of these statements are true More than one correct ans.
Respuesta
  • Z line – Where the myosin filaments are anchored
  • M line – Where the myosin filaments are anchored
  • A band – The length of a myosin filament, may contain overlapping actin filaments
  • I band – Contains only actin filaments
  • H Zone- Contains only myosin filaments
  • All are true
  • None are true

Pregunta 49

Pregunta
Which is true for Troponin T
Respuesta
  • Connect troponin to Tropomyosin
  • Suppress interaction between actin and myosin in absence of Ca2+
  • Reversible connection with Ca2+ when concentration of Ca2+ is high enough

Pregunta 50

Pregunta
Which best describes Isometric muscle contraction?
Respuesta
  • Muscles shortens in length in relationship to the production of movement (i.e. push ups)
  • Muscle length remains the same, no movement occurs but the force (muscle tension) is increased above tonic levels to resist gravity or other forces i.e. holding a shopping bag
  • Contraction against increasing force

Pregunta 51

Pregunta
[blank_start]Isotonic[blank_end]: Muscles shortens in length in relationship to the production of movement (i.e. push ups) [blank_start]Isometric[blank_end]: Muscle length remains the same, no movement occurs but the force (muscle tension) is increased above tonic levels to resist gravity or other forces i.e. holding a shopping bag [blank_start]Auxotonic[blank_end]: Contraction against increasing force
Respuesta
  • Isotonic
  • Isometric
  • Auxotonic

Pregunta 52

Pregunta
Force<load therefore axotonic/eccentric contraction speed of contraction (V) is
Respuesta
  • Slow
  • Fast
  • Stays the same

Pregunta 53

Pregunta
Electromechanical connection is the dependence between membrane potential and
Respuesta
  • The contractile activity (CA)
  • Just the membrane potential
  • None of these

Pregunta 54

Pregunta
How long is the latent period between stimuli and muscle contraction
Respuesta
  • 2-3 ms
  • 2-3 sec
  • No latent period
  • 12-13 ms
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