Immunology 2

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Resumen del Recurso

Pregunta 1

Pregunta
Which options are primary lymphoid organs?
Respuesta
  • Thymus
  • Bone marrow
  • Spleen
  • Peyer's patches
  • MALT

Pregunta 2

Pregunta
Which options are secondary lymphoid organs?
Respuesta
  • MALT
  • Spleen
  • Lymph nodes
  • Thymus
  • Bone marrow

Pregunta 3

Pregunta
Dendritic cells are derived from lymphoid and myeloid precursors.
Respuesta
  • True
  • False

Pregunta 4

Pregunta
Platelets are derived directly from pluripotent stem cells.
Respuesta
  • True
  • False

Pregunta 5

Pregunta
Which options do not express MHC Class 1?
Respuesta
  • Red blood cells
  • Platelets
  • Neutrophils
  • B cells
  • T cells

Pregunta 6

Pregunta
Naive B cells are derived from the
Respuesta
  • Bone marrow
  • Thymus
  • Spleen
  • MALT

Pregunta 7

Pregunta
CD4+ T cells recognise
Respuesta
  • MHC Class 1
  • MHC Class 2

Pregunta 8

Pregunta
CD8+ T cells recognise
Respuesta
  • MHC Class 1
  • MHC Class 2

Pregunta 9

Pregunta
CD16 and CD56 are both found on
Respuesta
  • NK cells
  • Macrophages
  • B cells
  • T cells

Pregunta 10

Pregunta
All leukocytes express
Respuesta
  • CD45
  • CD19
  • CD68
  • CD59

Pregunta 11

Pregunta
The most abundant leukocyte in circulation are...
Respuesta
  • Neutrophils
  • Macrophages
  • B cells
  • CD8+ T cells

Pregunta 12

Pregunta
Monocytes and Macrophages help to produce components involved in the complement system
Respuesta
  • True
  • False

Pregunta 13

Pregunta
Macrophages are able to present antigens on their surface
Respuesta
  • True
  • False

Pregunta 14

Pregunta
Monocytes have CD.....
Respuesta
  • 14
  • 56
  • 16
  • 15

Pregunta 15

Pregunta
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Respuesta
  • Phagolysosome
  • Early endosome
  • Endophagosome

Pregunta 16

Pregunta
Which granulocytes have major basic protein in their granules?
Respuesta
  • Eosinophils
  • Basophils
  • Neutrophils

Pregunta 17

Pregunta
Which granulocytes have lactoferrin in their granules?
Respuesta
  • Neutrophils
  • Eosinophils
  • Basophils

Pregunta 18

Pregunta
Which granulocytes do not have histamine in their granules?
Respuesta
  • Eosinophils
  • Neutrophils
  • Basophils

Pregunta 19

Pregunta
Which granulocytes have chondroitin sulphate in their granules?
Respuesta
  • Neutrophils
  • Eosinophils
  • Basophils

Pregunta 20

Pregunta
Which of these are reactive oxygen species?
Respuesta
  • Hypochlorous acid
  • Hydrogen peroxide
  • Superoxide
  • Water

Pregunta 21

Pregunta
The only antimicrobial peptides that macrophages use are...
Respuesta
  • Cathelicidins
  • Azurocidin
  • Defensins
  • Histatins

Pregunta 22

Pregunta
Acidification by neutrophils or macrophages is...
Respuesta
  • Bacteriocidal
  • Bacteriostatic
  • Can be both

Pregunta 23

Pregunta
Both macrophages and neutrophils produce ROS's.
Respuesta
  • True
  • False

Pregunta 24

Pregunta
Both macrophages and neutrophils produce NETs.
Respuesta
  • True
  • False

Pregunta 25

Pregunta
The most potent antigen present cell is...
Respuesta
  • Dendritic cells
  • Macrophages
  • Monocytes
  • B cells

Pregunta 26

Pregunta
Label the features of platelets
Respuesta
  • platelet
  • ctivating
  • fibrinogen
  • ytokines
  • C3b

Pregunta 27

Pregunta
Most T cells are...
Respuesta
  • CD4 positive but CD8 negative
  • CD4 positive and CD8 positive
  • CD8 positive but CD4 negative

Pregunta 28

Pregunta
Which cytokine results in a T cell receptor being produced on an immature T cell?
Respuesta
  • IL-7
  • IL-10
  • GM-CSF
  • TNF-a

Pregunta 29

Pregunta
Self molecules are said to induce...
Respuesta
  • Tolerance
  • Multi-specificity
  • Immunogenicity

Pregunta 30

Pregunta
What is negative selection?
Respuesta
  • T cells with a high affinity for self antigens are killed by apoptosis
  • T cells with a high avidity for self antigens are killed by apoptosis
  • T cells with a low affinity for self antigens are killed by apoptosis
  • T cells with a low affinity for self antigens are allowed to mature

Pregunta 31

Pregunta
What is positive selection?
Respuesta
  • T cells with a low affinity for self antigens are allowed to mature
  • T cells with a high affinity for self antigens are allowed to mature
  • T cells with a high affinity for self antigens are killed off by apoptosis
  • T cells with a low affinity for self antigens are killed off by apoptosis

Pregunta 32

Pregunta
The majority of T cells do not make it through negative selection.
Respuesta
  • True
  • False

Pregunta 33

Pregunta
T cells without any stimulation also die off.
Respuesta
  • True
  • False

Pregunta 34

Pregunta
What CD do T regulatory cells have?
Respuesta
  • 4
  • 19
  • 8

Pregunta 35

Pregunta
Which cells do TH1 helper cells activate?
Respuesta
  • Macrophages
  • B cells
  • Any nucleated cell
  • Stromal cells

Pregunta 36

Pregunta
Which cells do TH2 helper cells activate?
Respuesta
  • B cells
  • Macrophages
  • T cells
  • Stromal cells

Pregunta 37

Pregunta
Which cells do TH17 helper cells activate?
Respuesta
  • Stromal cells
  • B cells
  • Macrophages
  • T cells

Pregunta 38

Pregunta
What is the main effect of T reg cells?
Respuesta
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Pregunta 39

Pregunta
What is the main effect of TH2 cells?
Respuesta
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Pregunta 40

Pregunta
What is the main effect of TH1 cells?
Respuesta
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Pregunta 41

Pregunta
What is the main effect of TH17 cells?
Respuesta
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Pregunta 42

Pregunta
Which cytokine(s) tend to be released by TH17 cells?
Respuesta
  • IL-7
  • IL-17
  • TGF-beta
  • IL-10

Pregunta 43

Pregunta
Which cytokine(s) tend to be released by TH1 cells?
Respuesta
  • IL-7
  • IL-10
  • IFN-gamma
  • TGF-beta

Pregunta 44

Pregunta
Which cytokine(s) tend to be released by TH2 cells?
Respuesta
  • IL-4
  • TNF-a
  • TNF-b
  • PGD2

Pregunta 45

Pregunta
Which cytokine(s) tend to be released by CD8+ cells?
Respuesta
  • IFN-gamma
  • TNF-a
  • TGF-b
  • IL-4

Pregunta 46

Pregunta
What feature on T cells helps to induce proliferation B cells?
Respuesta
  • CD40
  • CD40 Ligand
  • mIgM
  • CD45

Pregunta 47

Pregunta
B cells have complement receptors.
Respuesta
  • True
  • False

Pregunta 48

Pregunta
As well as perforin and granzyme to kill target cells, NK cells have...
Respuesta
  • NK Cytotoxic factor
  • CD40 Ligand
  • Major basic protein
  • Lyophosphatase

Pregunta 49

Pregunta
Interferon gamma is produced by NK cells - what is its function?
Respuesta
  • Activate phagocytes
  • Activates B cells
  • Induces proliferation of T cells

Pregunta 50

Pregunta
NK cells have a T cell receptor.
Respuesta
  • True
  • False

Pregunta 51

Pregunta
T cells are the most abundant lymphocytes.
Respuesta
  • True
  • False
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