7253915
Pregunta 1
Pregunta
How many weeks constitute a term pregnancy?
Respuesta
-
24-30 weeks
-
30-35 weeks
-
37-42 weeks
-
44-46 weeks
Pregunta 2
Pregunta
Fill the table below with the appropriate Physiologic/Pharmacokinetic changes
Respuesta
-
increase in hepatic metabolism
-
decrease in hepatic metabolism
-
thinning of barrier
-
thickening of barrier
-
increased renal blood flow
-
decreased renal blood flow
-
increased blood volume
-
decreased blood volume
-
increased albumin concentration
-
decreased albumin concentration
-
decrease motility
-
increased motility
-
increased intestinal blood flow
-
decreased intestinal blood flow
-
increased gastric pH
-
decreased gastric pH
-
increase metabolism
-
decreased metabolism
-
increased distribution
-
decreased distribution
-
increased GFR
-
decreased GFR
-
increased elimination
-
decreased elimination
-
increased distribution
-
decreased distribution
-
increased protein binding
-
decreased protein binding
-
increased absorption
-
decreased absorption
-
increased concentration
-
decreased concentration
-
increased maternal concentration
-
decreased maternal concentration
-
increased fetal concentration
-
decreased fetal concentration
-
increased concentration
-
decreased concentration
-
increase concentration
-
decrease concentration
-
increased free drug concentration
-
decreased free drug concentration
-
increased concentration
-
decreased concentration
Pregunta 3
Pregunta
Which of the following are true in regards to medication use in pregnancy? (select all that apply)
Respuesta
-
eliminate nonessential drugs
-
discourage self-medication
-
minimize exposure to harmful medications
-
adjust doses for use during pregnancy
Pregunta 4
Pregunta
What vaccinations should be administered during pregnancy?
Respuesta
-
Inactivated influenza vaccine
-
Tdap ( @ 27-36 weeks)
-
Hepatitis B
-
Hepatitis A
-
Meningitis
Pregunta 5
Pregunta
Why are multivitamins used during pregnancy?
Respuesta
-
fetal bone development
-
maternal and fetal erythropoiesis
-
prevent neural tube defect
Pregunta 6
Pregunta
Why is calcium used during pregnancy?
Respuesta
-
maternal and fetal erythropoiesis
-
fetal bone development
-
prevent neural tube defect
-
prevention of HTN
Pregunta 7
Pregunta
[blank_start]Folic acid[blank_end] is used during pregnancy to prevent neural tube defects
Respuesta
-
Folic acid
Pregunta 8
Pregunta
Drugs with a molecular weight of less than [blank_start]600[blank_end] daltons readily cross the placenta barrier.
Respuesta
-
600
Pregunta 9
Pregunta
Lipophilic drugs will cross the placental barrier more than hydrophilic drugs
Respuesta
- True
- False
Pregunta 10
Pregunta
Which albumin levels are higher, fetal or maternal?
Respuesta
-
fetal
-
maternal
Pregunta 11
Pregunta
Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier
Respuesta
- True
- False
Pregunta 12
Pregunta
Only [blank_start]unbound[blank_end] drugs can cross placental membranes
Respuesta
-
unbound
Pregunta 13
Pregunta
Blood flow to [blank_start]uterus[blank_end] impacts drug transfer to fetus
Respuesta
-
uterus
Pregunta 14
Pregunta
What is the drug of choice for the treatment of hyperemesis gravidarum?
Respuesta
-
ondansetron
-
pyridoxine
-
doxylamine
-
phosphoric acid
Pregunta 15
Pregunta
The treatment of choice for nausea and vomiting during pregnancy is [blank_start]nonpharmacological treatment[blank_end]
Respuesta
-
nonpharmacological treatment
-
pyridoximine and doxylamine
-
emetrol
Pregunta 16
Pregunta
What is the first line or drug of choice for nausea and vomiting during pregnancy?
Respuesta
-
pyridoxine
-
doxylamine
-
phosphoric acid
-
metoclopramide
Pregunta 17
Pregunta
For nausea and vomiting during pregnancy, [blank_start]phosphoric acid[blank_end] should not be used if the patient is a diabetic
Respuesta
-
phosphoric acid
-
metoclopramide
-
dopamine
-
diclegis
Pregunta 18
Pregunta
Nausea and Vomiting
2nd line therapy is [blank_start]metoclopramide[blank_end]
3rd line therapy is [blank_start]dopamine antagonist[blank_end]
Respuesta
-
metoclopramide
-
ondansetron
-
doxylamine
-
promethazine
-
dopamine antagonist
-
dicelgis
-
ondansetron
-
methylprednisone
Pregunta 19
Pregunta
First line line treatment for constipation during pregnancy is incerase [blank_start]fiber[blank_end] and [blank_start]fluid[blank_end] intake
Respuesta
-
fiber
-
fluid
Pregunta 20
Pregunta
What drugs should not be used to treat constipation during pregnancy?
Respuesta
-
osmotic laxatives
-
docusate
-
castor oil
-
mineral oil
-
senna
-
bsicodyl
Pregunta 21
Pregunta
GERD/Heartburn
1st line: [blank_start]Lifestyle Modifications[blank_end]
2nd line: [blank_start]antacids or sucralfate[blank_end]
Respuesta
-
Lifestyle Modifications
-
antacids or sucralfate
-
metoclopramide
-
PPIs
-
antacids or sucralfate
-
sodium bicarbonate
-
Ranitidine
-
PPIs
Pregunta 22
Pregunta
Which of the following treatment can be used to treat Hemorrhoids during a pregnancy?
Respuesta
-
Higher fiber intake
-
increase oral fluid intake
-
use sitz baths
-
Topical anesthetics, protectants, and astringents
-
tylenol
Pregunta 23
Pregunta
Bulk forming agents should be utilized to treat diarrhea during pregnancy, what drugs should be avoided?
Respuesta
-
Diphenoxylate/atropine
-
paregoric
-
bismuth subsalicylate
-
psyllium/fiber
Pregunta 24
Pregunta
Saline nasal spray/drops are safe to use during pregnancy in the treatment of cough, colds, and allergies
Respuesta
- True
- False
Pregunta 25
Pregunta
What is the drug of choice to treat cold , cough, and allergies during pregnancy?
Respuesta
-
chlorpheniramine
-
diphenhydramine
-
loratidine
-
budesonide
Pregunta 26
Pregunta
What drugs are recommended during the 2nd and 3rd trimesters in the treatment of cough, cold, and allergies during pregnancy?
Respuesta
-
diphenhydramine
-
loratidine
-
cetirizine
-
beclomethasone
Pregunta 27
Pregunta
What nasal steroids are recommended for chronic allergies during pregnancy?
Respuesta
-
Budesonide (Rhinocort)
-
Beclomethasone (Beconase AQ)
-
Advair
Pregunta 28
Pregunta
[blank_start]Acetaminophen[blank_end] is the drug of choice for acute pain managment during pregnancy
Respuesta
-
Acetaminophen
-
opioids
-
NSAIDs
-
aspirin
Pregunta 29
Pregunta
What is the drug of choice in the treatment of HTN and severe eclampsia?
Respuesta
-
labetalol
-
hydralazine
-
IV magnesium
Pregunta 30
Pregunta
IV [blank_start]Magnesium[blank_end] is used for seizure protection and treatment
Respuesta
-
Magnesium
Pregunta 31
Pregunta
Pharmacological treatment for gestational HTN should be started if the systolic BP is greater than [blank_start]150-160[blank_end] OR the diastolic is greater than [blank_start]100-110[blank_end]
Respuesta
-
150-160
-
100-110
Pregunta 32
Pregunta
Essential/Gestational HTN
1st line (DOC): [blank_start]Methyldopa[blank_end]
2nd line: [blank_start]Labetolol[blank_end]
Respuesta
-
Methyldopa
-
Labetalol
Pregunta 33
Pregunta
Coagulation Disorders
You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies
Respuesta
- True
- False
Pregunta 34
Pregunta
Coagulation Disorders
1st line: [blank_start]LMWH[blank_end]
2nd line: [blank_start]UFH[blank_end]
Treatment is to be contiuned through pregnancy and [blank_start]6[blank_end] weeks after delivery (including breastfeeding)
Respuesta
-
LMWH
-
UFH
-
6
Pregunta 35
Pregunta
Which of the following drugs are contraindicated in the treatment of UTIs during pregnancy?
Respuesta
-
Cephalexin
-
Ampicillin
-
SMX-TMP
-
Fluoroquinolines
-
Tetracyclines
Pregunta 36
Pregunta
What are the top drug choices in the treatment of UTIs during pregnancy?
Respuesta
-
Cephalexin
-
Ampicillin
-
Nitrofurantoin
-
Tetracyclines
Pregunta 37
Pregunta
What drugs are utilized in the treatment of pyelonephritis?
Respuesta
-
Ceftriaxone
-
Ampicillin plus gentamicin
-
Ampicillin-sulbactam
-
nitrofurantoin
-
cephalexin
Pregunta 38
Pregunta
STI's
Drug of choice syphillis: [blank_start]penicillin G[blank_end]
Drug of choice for gonorrhea: [blank_start]cetriaxone[blank_end]
Durg of choice for chlamydia: [blank_start]amoxicillin[blank_end] ; 2nd line: [blank_start]ertthromycin[blank_end]
Respuesta
-
penicillin G
-
ceftriaxone
-
amoxicillin
-
erythromycin
-
ceftriaxone
-
penicillin G
-
amoxicillin
-
erythromycin
-
amoxicillin
-
ceftriaxone
-
penicillin G
-
erythromycin
-
erythromycin
-
amoxicillin
-
ceftriaxone
-
penicillin G
Pregunta 39
Pregunta
Acyclovir/valacyclovir is used in the treatment of genital herpes during pregnancy
Respuesta
- True
- False
Pregunta 40
Pregunta
[blank_start]Metronidazole[blank_end] is the treatment of choice for bacterial vaginosis, and the alternative treatment is clindaymcin
Respuesta
-
Metronidazole
Pregunta 41
Pregunta
Asthma
[blank_start]Albuterol[blank_end] is the short acting beta agonist of choice and [blank_start]budesonide[blank_end] is the inhaled corticosteriod of choice during preganancy
Respuesta
-
Albuterol
-
budesonide
Pregunta 42
Pregunta
During pregnancy, changing agents to minimize risk is NOT recommended for the treatment of epilepsy
Respuesta
- True
- False
Pregunta 43
Pregunta
What drugs are the safest to use to treat epilepsy during pregnancy?
Respuesta
-
lamotrigine
-
levetiracetam
-
valproic acid
-
carbamazepine
Pregunta 44
Pregunta
HIV during pregnancy
New diagnosed: [blank_start]HAART[blank_end]
[blank_start]Zidovudine[blank_end] is the mainstay of antiretroviral therapy
Avoid [blank_start]efavirenz[blank_end]
Respuesta
-
HAART
-
Zidovudine
-
efavirenz
-
clindamycin
-
Zidovudine
-
HAART
-
efavirenz
-
clindamycin
-
efavirenz
-
Zidovudine
-
HAART
-
clindamycin
Pregunta 45
Pregunta
Treatment of schizophrenia, bipolar disorder, depression usually needs to be continued during pregnancy and breastfeeding; high relapse rates if discontinued
Respuesta
- True
- False
Pregunta 46
Pregunta
What are the most preferred agents in the treatment of mental health issues in pregnant women?
Respuesta
-
fluoxetine
-
citalopram
-
escitalopram
-
levetiracetam
Pregunta 47
Pregunta
Nortriptyline and desipramine are TCAs of choice in the treatment of mental health issues during pregnancy
Respuesta
- True
- False
Pregunta 48
Pregunta
Treatment of choice for HYPOthryoridism: [blank_start]levothyroxine[blank_end]
Treatment of choice for HYPERthryroidism: [blank_start]propylthiouracil[blank_end] or [blank_start]methimazole[blank_end]
Respuesta
-
levothyroxine
-
propylthiouracil
-
methimazole
Pregunta 49
Pregunta
[blank_start]Tocolysis[blank_end] is the prcoess of stopping contractions
Respuesta
-
Tocolysis
Pregunta 50
Pregunta
What drugs are utilized in pre-term labor and tocolysis?
Respuesta
-
IV magnesium
-
terbutaline
-
nifedipine
-
promethazine
Pregunta 51
Pregunta
What drugs are needed for cervical ripening?
Cervical ripening: in order to dilate, collagen must loosen and separate; moisture necessary; occurs naturally in women who spontaneously enter labor
Respuesta
-
misoprostol
-
dinoprostone
-
oxytocin
-
methylergonovine
Pregunta 52
Pregunta
Labor induction
1st line: [blank_start]oxytocin[blank_end]
2nd line: [blank_start]methylergonovine[blank_end]
Respuesta
-
oxytocin
-
Methylergonovine
-
misoprostol
-
dinoprostone
-
methylergonovine
-
dinoprostone
-
misoprostol
-
Oxytocin
Pregunta 53
Pregunta
If mother colonized with Group B Streptococcus: [blank_start]Penicillin G[blank_end]
Respuesta
-
Penicillin G
Pregunta 54
Pregunta
Analgesia can prolong the 1st and 2nd stages of labor
Respuesta
- True
- False
Pregunta 55
Pregunta
[blank_start]Epidural[blank_end] analgesia has better profile than parenteral opioids (poor maternal pain relief and less vigorous neonates)
Respuesta
-
Epidural
Pregunta 56
Pregunta
Drug Factors General Guidelines
Most drugs appear in breast milk to some degree. Most common mechanism of transfer is passive diffusion.
Levels of most drugs in breast milk do not usually exceed 1% to 2% of ingested maternal dosage
If the milk/plasma ratio of drug and active metabolites is less than [blank_start]1:1[blank_end], it is usually safe to breastfeed
RID: If infant dose is less than [blank_start]10[blank_end]% of maternal dose (weight adjusted), it is usually safe to breastfeed
Respuesta
-
1:1
-
10
Pregunta 57
Pregunta
Depression
Sertraline and paroxetine are most frequently prescribed with few reported adverse effects,
Respuesta
- True
- False
Pregunta 58
Pregunta
breast milk is more acidic; weak bases are more likely to stay trapped in breast milk “ion trapping:
Respuesta
- True
- False
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