Pregunta 1
Pregunta
HIV and AIDS has a natural reservoir in monkeys. This virus most likely made the jump from monkeys to humans when:
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Humans engaged in sexual behaviour with monkeys.
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Humans started hunting monkeys.
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Scientists started on careless research with monkeys.
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Zoos were created, increasing monkey-human contact.
Pregunta 2
Pregunta
Dr. Gottlieb is:
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A doctor who noticed HIV starting to emerge.
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The doctor responsible for the outbreak of HIV.
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The first HIV patient in the US.
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A field doctor in Congo.
Pregunta 3
Pregunta
In 1981, with the emergence of HIV and AIDS, many young, homosexual males started coming down with Kaposi's sarcoma. Kaposi's sarcoma is:
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An extremely lethal brain cancer.
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A potentially lethal cancer of blood vessels.
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A completely benign skin cancer.
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A benign cancer in the lungs and throat.
Pregunta 4
Pregunta
In 1981, these two diseases were the most common indicators of people who had come down with HIV.
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Kaposi's sarcoma and PCP.
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PCP and pneumonia.
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Kaposi's sarcoma and small pox.
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Kaposi's sarcoma and measles.
Pregunta 5
Pregunta
Which of the following are ways HIV and AIDS can be transferred? Check ALL that apply.
Pregunta 6
Pregunta
Gaëtan Dugas was written about in the book 'And The Band Played On: Politics, People and the AIDS Epidemic'. He was an important figure in AIDS research because:
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For a long time he was mistakenly considered to be the index patient for AIDS.
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He was a prominent author who wrote about AIDS.
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He created to the first name of HIV, 'GRIDS'.
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He was a primary cause in the intravenous drug use transmission of HIV.
Pregunta 7
Pregunta
In response to HIV, the immune system is attacked, and antibodies cannot be generated quickly. This is why from 3 weeks to 6 months an antibody test on an infected person might mistakenly turn up a:
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false positive.
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false negative.
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true positive.
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true negative.
Pregunta 8
Pregunta
The first symptoms of HIV within the first two weeks commonly appears to be:
Pregunta 9
Pregunta
If you want the most accurate results for if you have HIV, you should get an antibody test.
Pregunta 10
Pregunta
The most common way for HIV to be transferred between mother and child is:
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Transplacentally in the womb.
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During the birth process.
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Postnatal breast feeding.
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Upon conception.
Pregunta 11
Pregunta
Giving an HIV-positive mother a dose of HIV drugs before birth and a dose to the child up to 72 hours after birth can greatly reduce likelihood of permanent HIV infection in the child.
Pregunta 12
Pregunta
Approximately what percent of all people living with AIDS live in Sub-Saharan Africa?
Pregunta 13
Pregunta
In HIV, the genome is contained in:
Pregunta 14
Pregunta
In order to make DNA out of their RNA, retroviruses like HIV use an enzyme called:
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Reverse transcriptase.
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RNAstase.
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Genome Inverstil.
Pregunta 15
Pregunta
In viral cell attachment, there are multiple steps. First, [blank_start]GP120[blank_end] must bind to two receptors to get into the host cell. Once in the cell, the virus' [blank_start]reverse transcriptase[blank_end] turns RNA into DNA. The enzyme [blank_start]integrase[blank_end] enables integration of viral DNA into cellular DNA. After this, the enzyme [blank_start]protease[blank_end] cleaves polypeptides into functional [blank_start]HIV-1 proteins[blank_end]. Lastly, the virus [blank_start]buds[blank_end] from the cell wall and leaves to infect other cells.
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GP120
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reverse transcriptase
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integrase
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protease
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buds
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HIV-1 proteins
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mRNA
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immune system
Pregunta 16
Pregunta
For HIV Chemotherapy, one of the treatments is HAART. HAART stands for:
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Highly Active Anti Retroviral Therapy.
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HIV Analysis And Removal Therapy.
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Heavily Aggressive Antigen Resource Treatment.
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Heat Activated Aorta Resonance Treatment.
Pregunta 17
Pregunta
Inhibitors of viral enzymes can be competitive or non-competitive. With competitive inhibitors, the inhibitor:
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Leaves substrate in the enzyme, preventing other substrate (the virus) from binding.
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Prevent integrase from inserting viral DNA into cellular DNA.
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Coats the outside of the cell, preventing the virus from budding out of the cell.
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Fights the viral enzymes directly.
Pregunta 18
Pregunta
The HAART treatment commonly helps patients survive:
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To their mid 30s.
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To the life expectancy they would have without HIV.
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10 years longer than they would have without HAART.
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Forever. HAART patients commonly become immortal.
Pregunta 19
Pregunta
All cells will make viruses once they are infected with HIV.
Pregunta 20
Pregunta
AZT is a competitive inhibitor for HIV. It stops reverse transcriptase from making viral DNA by:
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Integrating into the chain without a hydroxyl group, terminating the chain.
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Taking apart the reverse transcriptase.
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Preventing it from getting the necessary materials to make the DNA.
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Cutting the RNA into segments.
Pregunta 21
Pregunta
A similar competitive inhibitor to AZT, Lamivudine was initially used for HIV patients, but found to be more effective combating:
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Pertussis.
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Hepatitis B.
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Polio.
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AIDS.
Pregunta 22
Pregunta
This drug is used for best prevention of mother to child HIV transmission, as it is very safe:
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Nevirapine.
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Lamivudine.
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AZT.
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Integrase.
Pregunta 23
Pregunta
In America, these are the proportion of HIV infected individuals at each stage of care.
Of all patients with HIV,
80% - [blank_start]Are diagnosed.[blank_end]
62% - [blank_start]Are linked to HIV care.[blank_end]
41% - [blank_start]Are retained in HIV care.[blank_end]
36% - [blank_start]Are on antiretroviral therapy.[blank_end]
28% - [blank_start]Have a suppressed viral load.[blank_end]
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Are diagnosed.
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Are linked to HIV care.
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Are retained in HIV care.
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Are on antiretroviral therapy.
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Have a suppressed viral load.
Pregunta 24
Pregunta
HAART requires 5 years of continuous viral treatment with full adherence to eliminate HIV in the body.
Pregunta 25
Pregunta
During HAART treatment, it's possible for patients to experience ARV (anti-retroviral) failure. This is most commonly caused by:
Pregunta 26
Pregunta
To enter the Helper T cell, the HIV receptor must bind to two receptors:
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First, CD4, then CCR5.
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First, CCR5, then CD4.
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First, to the nucleus, then to the plasma membrane.
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First to the CD4, then to the genome.
Pregunta 27
Pregunta
Timmothy Brown is a famous patient in HIV treatment because:
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After a bone marrow transplant, he became HIV negative.
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He was the index case for HIV.
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His tears could heal other HIV patients.
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He survived to over 100 without any treatment whatsoever.
Pregunta 28
Pregunta
HIV most commonly attacks Helper T cells. This is is a problem because:
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Helper T cells are high on the immune system hierarchy, and T and B cells depend on them.
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Helper T cells are very low on the immune system hierarchy, so it's not that much of a problem.
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Helper T cells are at the top of the immune system hierarchy, and everything depends on them.
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Helper T cells are coated with CCR5, an important receptor that will lead to death if suppressed.
Pregunta 29
Pregunta
HIV can infect the brain if it's transported into it by this cell, which has clearance into the brain:
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Helper T Cells.
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Macrophages.
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Memory B Cells.
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Plasma Cells.
Pregunta 30
Pregunta
In HIV patients, the relationship between helper T cells and antibodies is commonly as follows:
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Antibody levels rise, and helper T cell levels rise.
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Antibody levels rise, and helper T cell levels lower.
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Antibody levels lower, and helper T cell levels lower.
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Antibody levels lower, and helper T cell levels rise.