L11 The Nucleus and DNA

Descripción

• Describe the basic structure and function of the nucleus. • Describe the structure of the nuclear pore complex and its role in nucleo-cytoplasmic exchange. • Describe the organisation of DNA within the nucleus. • Outline the functional differences between euchromatin and heterochromatin.
Mer Scott
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Mer Scott
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Resumen del Recurso

Pregunta 1

Pregunta
(Choose all correct.) The nucleus:
Respuesta
  • is the most prominent organelle.
  • has a diameter of 5-10 micrometres.
  • is present in almost all cells.
  • contains all of the cell's genetic information

Pregunta 2

Pregunta
The membrane of the nucleus is the:
Respuesta
  • nucleomembrane
  • nuclear membrane
  • nuclear envelope

Pregunta 3

Pregunta
Choose the incorrect statement about the nucleus.
Respuesta
  • It has four layers of phospholipids.
  • It has complex protein structures called pores.
  • Its inner surface is lined nuclear lamina, which is made of intermediate filaments.
  • Fluid within the lumen of the nucleus maintains its spherical shape.
  • Intermediate filaments aid in organising and packing chromatin.

Pregunta 4

Pregunta
What is the consequence of a dysfunctional nuclear lamina? (Choose all correct.)
Respuesta
  • Abnormally shaped nuclei
  • Progeria syndrome
  • Cystic fibrosis
  • Cerebral palsy
  • Poor mitogenesis/meiosis
  • Accelerated ageing
  • Slow development

Pregunta 5

Pregunta
Choose the incorrect statement about the nuclear pores.
Respuesta
  • They allow mRNA, rRNA, and tRNA to exit.
  • It allows control signals into the nucleus.
  • It mediates passage into and out of the nucleus.
  • Energy and cellular materials move out of the nucleus.

Pregunta 6

Pregunta
How much DNA is in the human nucleus?
Respuesta
  • 2.5 cm
  • 2.5 m
  • 25 cm

Pregunta 7

Pregunta
DNA is packed in the nucleus so that it is inaccessible until replication.
Respuesta
  • True
  • False

Pregunta 8

Pregunta
The DNA double helix is about [blank_start]2[blank_end]nm in diameter. Bundled into [blank_start]nucleosomes[blank_end] or "beads" using [blank_start]H2a, H2b, H3, and H4[blank_end] histone proteins, it is about [blank_start]10[blank_end]nm in diameter. Further interaction with [blank_start]H1[blank_end] histone proteins [blank_start]coils[blank_end] this into a [blank_start]30[blank_end]nm fibre. During replication this can be [blank_start]looped[blank_end] to form a [blank_start]300[blank_end]nm diameter [blank_start]chromosome[blank_end].
Respuesta
  • 2
  • nucleosomes
  • H2a, H2b, H3, and H4
  • 10
  • H1
  • 30
  • looped
  • coils
  • 300
  • metaphase chromosome
  • interphase chromosome

Pregunta 9

Pregunta
Which kind of chromatin is the denser, inactive form?
Respuesta
  • heterochromatin
  • euchromatin

Pregunta 10

Pregunta
The ratio of heterochromatin and euchromatin stays static during a cell's lifetime.
Respuesta
  • True
  • False

Pregunta 11

Pregunta
The location of chromosomes in the nucleus is not random.
Respuesta
  • True
  • False
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