L35 Microbial genetics – microbes and medicine

Descripción

• Outline the properties of the bacterial genome. • Outline the difference between vertical and horizontal gene transfer. • Outline the four strategies used by bacteria to generate genetic diversity (mutation, transformation, transduction and conjugation). • Describe how microorganisms exchange genes to alter their virulence. • Outline the lytic and lysogenic cycles of bacteriophage replication.
Mer Scott
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Mer Scott
Creado por Mer Scott hace casi 8 años
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Resumen del Recurso

Pregunta 1

Pregunta
Which statement best describes a plasmid?
Respuesta
  • A circular, self replicating piece of gene in the cytosol of viruses.
  • A small, circular, self replicating DNA segment in the cytosol of bacteria.
  • A small, circular, complex protein structure found in the plasma of bacteria.

Pregunta 2

Pregunta
A bacteria undergoes binary fission to create two genetically identical bacteria. Which method of gene transfer is this?
Respuesta
  • Vertical gene transfer
  • Horizontal gene transfer

Pregunta 3

Pregunta
In [blank_start]horizontal[blank_end] gene transfer, one trait is passed to another bacteria. In [blank_start]vertical[blank_end] gene transfer, the whole genome is passed on.
Respuesta
  • horizontal
  • vertical
  • vertical
  • horizontal

Pregunta 4

Pregunta
Which classic experiment demonstrates horizontal gene transfer?
Respuesta
  • Griffith's experiment
  • Koch's postulates
  • Avery's experiment

Pregunta 5

Pregunta
Which type of horizontal gene transfer involves a pilus used to make cell-to-cell contact?
Respuesta
  • Transduction
  • Transformation
  • Conduction

Pregunta 6

Pregunta
Which statement describes transduction?
Respuesta
  • Transfer of DNA from one bacteria to another via a bacteriophage
  • The uptake of naked short fragments of DNA by naturally transformable bacteria
  • Transfer of DNA via a pilus using cell to cell contact

Pregunta 7

Pregunta
The uptake of naked short fragments of DNA by naturally transformable bacteria is a form of horizontal gene transfer called transduction.
Respuesta
  • True
  • False

Pregunta 8

Pregunta
In the lytic cycle, the virus uses the [blank_start]bacterial[blank_end] cellular machinery to assemble more bacteriophages. When the capsid is assembled, the intention is for it to contain it's own [blank_start]viral[blank_end] DNA. However, plastids from the [blank_start]cytosol[blank_end] containing [blank_start]bacterial DNA[blank_end] can be incorporated into the bacteriophage too. If this bacteriophage goes on to infect a different bacteria in a [blank_start]lysogenic[blank_end] cycle, the bacterial DNA from the first bacteria will be transferred to the second and [blank_start]incorporated[blank_end] into its DNA.
Respuesta
  • bacterial
  • viral
  • cytosol
  • bacterial DNA
  • lysogenic
  • lytic
  • incorporated
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