Cognitive Neuroscience: Structure and Function of the Nervous System

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Fichas sobre Cognitive Neuroscience: Structure and Function of the Nervous System, creado por Savannah Duggan el 05/10/2017.
Savannah Duggan
Fichas por Savannah Duggan, actualizado hace más de 1 año
Savannah Duggan
Creado por Savannah Duggan hace alrededor de 7 años
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Principle 1: Perception - 'Reality' is an approximation based on sensory experience, skewed by adaptivity for survival
Principle 2: Constant change - Neuroplasticity: experiences alter brains organization, adjustments for learning and memory with new and changed neural connections
Principle 3: Contralaterality - Each Hemisphere receives sensory stimulation from the opposite side of the body (contralateral control too)
Principle 4: CNS Levels - basic animals have spinal cords (worms), then brainstems (fish), then forebrains - each additional level of the CNS adds behavioural complexity on top of the existing functions
Principle 5: Symmetry - left and right hemispheres look like mirror images but have some dissimilar features: language is most on the left, spatial function is mostly on the right
Principle 6: Organization - Hierarchy: light enters eye, processed for colour & shape, then identified - Parallel: vision info processed separately and concurrently to determine object vs to identify its motion - subsystems in multiple parallel pathways, but we have one unified experience
Principle 7: Sensory and motor - both divisions exist throughout the nervous system - spinal nerves (dorsal vs ventral roots) - separate sensory and motor cortical areas
Principle 8: Sensory input - divided into object recognition and motor control - dorsal (guides movement) & ventral (identifies objects) visual processing - animals with complex brain evolved separate systems for these two functions
Principle 9: Regional function - localization and aggregation - local damage = restricted symptoms, but widespread can = total function loss - small injury could heavily impact one portion of language ability, but widespread damage required to impact all language abilities
Principle 10: Excitation/inhibition - all neurons have spontaneous rate of activity that can be either increased or decreased - some neurons spread excitement, some spread inhibition
CNS Central nervous system: Forebrain, Brainstem and Spinal Cord
PNS -Peripheral nervous system: -Somatic: spinal and cranial nerves carrying sensory information to the CNS and instructions back out for movement -Autonomic: prepares internal organs for fight/flight & rest/digest, basic functions
Afferent vs Efferent Aff = going TO the CNS Eff = going AWAY fromt he CNS
Autonomic Nervous System - part of the PNS - Sympathetic: mobilization, adrenaline, fight or flight mode - Parasympathetic: conserves energy, rest and digest
Dermatome area of skin connected to the CNS (afferent nerve fibers) by one spinal-cord dorsal root
Dorsal fibers Afferent, from sensory receptors to CNS
Ventral fibers Efferent, from spinal cord to muscles
Gyrus Surface feature of brain: Small protrusion formed by folding of the cerebral cortex plural: gyri
Sulcus Surface feature of brain: Groove in brain matter, usually found in neocortex or cerebellum plural: sulci
Fissure Surface feature of brain: Very deep sulcus, or groove
Cerebral Cortex thin sheet of nerve tissue (3-4mm thick) folded many times to fit inside the skull
The Lobes -Frontal (executive function; forehead) -Parietal (perception; crown) -Temporal (memory, auditory, olfactory, taste; temples) -Occipital (visual; back)
Cerebrum major structure of the forebrain 2 almost identical hemispheres (L & R)
Cerebellum coordination of motor skills, balance
Brainstem -Central structure: hindbrain, midbrain, diencephalon (thalamus & hypothalamus) -most unconscious behaviour
Four ventricles cavities in the brain that contain cerebrospinal fluid (CSF)
Gray matter areas of nervous system mostly: cell bodies and blood vessels
White Matter areas of the nervous system most rich in myelinated neural axons
Corpus callosum fiber system connecting left and right hemispheres
Neurons ~ 86 billion brain's major functions, computation, cmns
Glial cells ~ 100 bil, aid/modulate neuron activity - Ependymal: secrete CSF - Astrocyte: transport between neurons and capillaries, blood-brain barrier Microglial- phagocytosis, scavenge debris Oligodendroglial: myelinate CNS Schwann: myelinate PNS
Nucleus group of cells forming a cluster, identifiable with stains (ie golgi or nissl), functioning group of cells that often work together
Nerve large collection of axons coursing together OUTSIDE the CNS
Tract large collection of axons coursing together WITHIN the CNS
Spinal Cord -directly generates most body movements - usually instructed by the brain but can also act on its own - spinal reflex: automatic movement, hard to prevent, knee-jerk reflex
Hindbrain - part of brain stem - Integrates in/voluntary body movement -Oldest part of brain (evolutionarily) - cerebellum, reticular formation, pons, medulla
Reticular Formation Reticular activating system: regulation of sleep-wake behaviour and behavioural arousal
Pons "Bridge" - connects cerebellum to the rest of the brain and controls important movements in the body
Medulla controls breathing and heart rate
Diencephalon hypothalamus and thalamus
Hypothalamus temperature regulation, eating, drinking, sexual behaviour (homeostasis)
Thalamus information form all sensory systems is integrated and projected into the appropriate region of the neocortex
Neocortical layers -differ in cell types and density, differences in appearance relate to function - afferent connect to layer 4 from thalamus and layers 2 and 3 - efferent in layers 5 and 6 connect to other parts of brain
Basal Ganglia control coordination and movement patterns, not muscle activation voluntary and involuntary movement
10 principles of neuroscience Perception, neuroplasticity, contralaterality, multi-level CNS, symmetry, unified experience, sensory and motor integration, localization/aggregation, dorsal/ventral, excitation/inhibition
Limbic System regulates: emotional/sexual behaviour, memory, spatial navigation
neuron structure
sensory neurons bring info to cns
Interneurons associate sensory and motor activity within CNS
Motor Neurons send signals from brain and spinal cord to muscles
Resting potential more negative Intracellular than extracellular inside of membrane = -70 millivolts relative to the outside intra = A- and K+ extra = N+ and Cl-
Hyperpolarization increase in electrical charge, more negative due to: inward flow of chloride ions or outward flow of potassium ions
Depolarization Decrease in electrical charge across membrane (more positive) influx of sodium ions, open gate
Action Potential sudden reverse in voltage, intracellular becomes positive relative to extracellular side due to Na+ entry, then reverses with K+ exit to return to resting potential
Saltatory Conduction propagation of an action potential at successive nodes or ranvier
EPSP Excitatory PostSynaptic Potential brief depolarization of a neuron, response to influx of NA+ more likely to produce action potential
IPSP Inhibitory PostSynaptic Potential Hyperpolarization of neuron membrane due to efflux of K+ or influx of Cl- less likely to produce action potential
Temporal summation pulses that occur at the same time on a membrane are summed
Spatial summation pulses that occer in the same place on a membrane are summed
Synapse/action potential
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