Lecture 12 - Parasites and climate change

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Degree Parasitology Fichas sobre Lecture 12 - Parasites and climate change, creado por Thalia Groom el 03/12/2014.
Thalia Groom
Fichas por Thalia Groom, actualizado hace más de 1 año
Thalia Groom
Creado por Thalia Groom hace alrededor de 10 años
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Pregunta Respuesta
What are the two most important reasons for the spread of plant pathogens? 1. Introduction 2. Weather
List four ways that global warming will affect vector-bourne disease Increased vector development Prolonged favourable conditions Increased winter survival Increaed geographical range
In what decade began the pole-ward shift of pests? 1960s
List 3 caveats to the pole-ward shift of pathogens 1. Richer countries detect pathogens sooner 2. Agricultural varieties have increased range of hosts 3. Geographical barriers such as the Sahara desert may effect southward movement
Why do countries at greater latitudes have to increase surveillence? Greatest productivity per area
Why will rate of mortality also increase in pathogens due to global warming? Increased number of their predators
Give an example of which warmer winters will negatively effect the parasite and where will this occur? Nematodes Temperate areas
Give an example of which global warming will positively effects pests and where will this occur? Larvae Colder climates
When are ewes most susceptible to blow fly strike and why? During the spring and summer because of their wet/soiled fleeces
How can the susceptibility of blowfly strike be reduced? sheering
Why are lambs more susceptible to blow fly strike after sheering? Growing fleeces and GI nematode infections
What effect does global warming have on the presence of blowfly? Strikes occur earlier in the year and the blowfly population will be larger
What can be done to prevent earlier blow fly strikes? Sheer sheep earlier i.e. early April
How does the medium risk model predict prevalence of malaria in 2050? Increased risk for 23 million people
How does the high-risk model predict outcome of malaria in 2050? Decreased risk for 25 million people
List 3 animals affected by bluetongue Mostly common in fine-wool sheep Also ruminents like white-tailed deer Sporadic in cattle
List 5 symptoms of bluetongue fever depression lameness oedema of lips conjunctivitis
List four outcomes of BT Decreased fertility Decreased milk-yeild Weight loss Wool break
What cells of the sheep does the virus infect intitially? Mid gut cells
After replication where does the virus relocate to? Haemocoel
After that, where does the virus infect and replicate? salivary glands
What is meant by the term extrinsic incubation period? Time from ingestion to the salivary glands
How is the blue-tongue spread? vector-bourne midges - culicoides
What type of virus is BTV? DS-RNA
How many RNA segments does BTV have? 10
What 3 structure make up the viral shell? sub-core, outercore, and outercapsid
What structural proteins make up the outercapsid and determine the serotype? VP2 AND VP5
How many serotypes of BTV are there? 24
What process can cause antigenic shift in BTV? Genetic reassortment
Name three species of culicoide midges and where they are distrubuted C.imicola - Africa C.sonorensis - N.America C.brevitarsis - Australia
What enzyme largely controls the time between blood meal and a new infection? RNA Polymerase
What is the optimum temp for this enzyme? 30 degrees - few days
What happens to the course of infection over winter? Infection stops
What is the name given to the emergence of parasitism after its disruption during winter? overwintering
Where and when was BTV first described? 1905 in South Africa
What year and where was the non-African outbreak? Cyprus 1943
Before 2005, what was the most severe outbreak of BTV in southern Europe? 1956 - Iberia 180 000 animals died
What 5 serotypes are present around the Mediterranean basin? 1,2,4,9,16
What was the traditional vector for BTV? c.imicola
What species were isolated from traps in Italy? C.pulcaris C.obsoletus
Which countries successfully implemented a vaccine against which strain of BTV? SPAIN AND PORTUGAL BTV-1
What serotype caused the first ever outbreak in northern europe and where? serotype 8 netherlands
How was this outbreak stopped? Winter of 2007 haulted transmission
Give 2 reasons thought to be the cause for the BTV-8 outbreak? Movement of infected animal or vectors Illegal african vaccine was used containing live virus
What event occurred that lead to a new outbreak of BTV in June 2007? Virus overwintered in Germany
What was the economical burden of the BTV? 60000 farms affected costing >150 million euros
What allowed UK to be declared BTV-8 free in 2008? They opted for the attenuated BTV vaccine
Give four reasons why the BTV-8 outbreak was so disastrous Never seen BTV or traditional vector before Very mild climate Lax vaccination attitude No programme monitoring Culicoides
List two other diseases spread by cullicoides Epizootic haemorrhagic disease African horse sickness
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