Quiz 3: Top 200 Drug Quiz

Pregunta	Respuesta
Drospirenone w/ Ethinyl Estradiol	Brand: Yasmin, Zarah, Syeda, Ocella sig: 1 QD [start on the 1st day of menstrual cycle OR on the Sunday after the onset of the menstrual period] AEs: Cardiovascular or thromboembolic disorders. Counseling: (1) Talk to a PCP immediately if you experience sharp chest pains, SOB, coughing blood, calf pain, chest tightness, sudden severe headache or vomiting, dizziness, numbness of arms or legs, breast lumps, severe pain in the stomach area, jaundice or signs of depression. (2) if 1 yellow tablet is missed, take it ASAP or take 2 tabs the next day, then continue the normal regimen. (3) Use a 2nd form of birth control during the 1st week of therapy. 4. see more from the card***
Norgestimate and Ethinyl Estradiol	Brand: Ortho-Cyclen, Sprintec Sig: 1 qd for 28 days [Start 5th day of the cycle] DDI: Ampicillin, amoxicillin, metronidazole, Tetracycline AEs: (1) may cause mental depression, fluid retention and depress folate levels. (2)Edema, unusual tiredness or weakness, Cardiovascular and thromboembolic disorders. Counseling: same as Drospirerone + EE
Estrogens (conjugated) (BEER LIST]	Brand: Premarin sig: 1.25 QD for VSM associated w/ menopause (Start on day 5 of cycle, if menstruating] DDI: May increase the toxic effect of corticosteroids AEs: Rash, acne, alopecia, hirsutism, edema, cervical secretions, pyrexia, insomnia, nausea, somnolence. Counseling: (1) increase risk of stroke, DVT, Endometrial cancer in women age > 65 yo, dementia (2) Report to your PCP side effects like pain in the legs, coughing blood, abnormal vaginal bleeding, skin yellowing, and abdominal pain.
Progesterone (oral)	Brand: Prometrium sig: 200 mg qd in the EVENING for 12 days sequentially per 28 day cycle. DDI : Ketoconazole may inhibit metabolism. AES: dizziness, headache, abd pain, musculoskeletal pain, viral infection, breast pain, nausea and diarrhea, fatigue, cough and irritability, blurred or loss of vision. Counseling: (1) EPT may increase the risk of cardiovascular disorders, breast cancer, endometrial cancer and in women over 65 years of age, probably dementia. (2) Do not take if allergic to peanuts
Norethindrone, Ethynyl Estra, Iron	Brand: Loestrin FE, Microgestin FE, Jummel FE sig: 1 QD for 28 days [Start on the 5th day of the cycle] DDI: ampicillin, amoxicillin, metronidazole, tetracycline AEs: (1) mental depression, fluid retention, depressed serum folate levels. (2) abd cramping, acne, anorexia, nausea, vomiting, edema, unusual tiredness or weakness, cardiovascular or thromboembolic disorders. Counseling: (1) same as Drospirenone + EE.
Estradiol [BEER LIST] [Tab, patch, ring insert, ]	Brand: See Below, Femring, Estring, Vagifem (Suppository) Estrace cream DDI: Ketoconazole, grapefruit juice AEs: (1) ET can increase risk of stroke, DVT, Endometrial cancer and probable dementia. (2) edema, thromboembolic disorder, depression, irritation of application site (3) increase of risk of gall bladder disease, high BP, decreased glucose intolerance, hypercalcemia Counseling: (1) avoid application sites that are oily, damaged, irritated or wet
Medroxyprogesterone (oral)	Brand: Provera Sig: beginning on the calculated 16th or 21st day of the menstrual cycle, 5 - 10 mg daily for 5 - 10 days. Counseling: Use w/ caution in diabetic patients because glucose tolerance may be decreased
Testosterone [BEERS LIST]	Brand: Andogel, Fortesta, Testim Sig: 50 mg applied QD Counseling: (1) Apply to clean, dry skin once daily (2) Allow area to dry before covering w cloth (3) Avoid showering or swimming for 2 hrs after application. (4) READ THE CARD FOR MORE *** Monitor: Hcrt, Hgb, Serum Testosterone, PSA, Lipid panel, LFT
Levothyroxine	Brand: Synthroid, Levoxyl, Levothroid Sig: 25 -300 mcg PO QD Counseling: Take on an empty stomach, 1hr b4 or 2hrs after meal Monitor: TSH
Liothyronine	Brand: Cytomel, Triostat Sig: 25 mcg PO QD AEs: AEs are indicative of high doses and include, Headache, irritability, nervousness, sweating, arrhythmia, increased bowel motility and menstrual irregularities Monitor: TSH, Serum T4, INR
Thyroid [BEER LIST]	Brand: Armour Thyroid Sig: 60 -180 mg QD Counseling: Talk to your PCP if signs of hyperthyroidism (overdose) occurs. Monitor: TSH
Alfuzosin	Brand: Uroxatral Sig: 1 QD + food, w/ the same meal everyday Counseling: (1) Take w/ food to increase absorption (2) Do not chew or crush tablets (3) May cause dizziness or drowsiness Monitor: BP
Dutasteride	Brand: Avodart Sig: 0.5 mg PO QD Counseling: (1) Women who are pregnant shd not come into contact w/ Dutasteride capsules. (2) Mens shd not donate blood until at least 6 months after their last dose. Monitor: PSA
Finasteride	Brand: Proscar Sig: 5 mg PO QD Counseling: Women who are or plan to become pregnant shd not handle crushed finasteride tablets or be exposed to semen from a patient who is taking proscar. Monitor: PSA
Tamsulosin	Brand: Flomax Sig: 0.4 mg cap QD [Given one - half hour following the same meal every day]. Counseling: Take dose one-half hour following the same meal every day. May cause dizziness, especially when rising from the sitting position.
Alendronate	Brand: Fosamax Sig: 10 mg QD or 70 mg Qwkly. Counseling: (1) Doses must be swallowed w/ 6 - 8 ounces of plain water immidieately upon arising from the day (at least 30 mins b4 the 1st food, beverage, or medication of the day) (2) Do not lie down for 30 mins after swallowing the tablet and not until the 1st food of the day has been consumed. Monitor: BMD
Raloxifene	Brand: Evista Sig: 60 mg PO QD w/ or w/o meal or time of the day. Counseling: advisable to take calcium and Vit D supplement if dietary intake is inadequate.
Hydroxychloroquine	Brand: Plaquenil Sig: 400 - 600 mg QD AEs: Visual disturbance, blood dyscrasias, abnormal skin pigmentation Counseling: Talk to your PCP if any of the following occur: Flu-like symptoms, aches, soreness of the mouth, gums, or throat, sore joints visual disturbance or any unusual bleeding or bruising. Monitor: Annual eye Exam***
Anastrozole	Brand: Arimidex Sig: 1 mg QD AEs: (1) May cause reduction in bone mineral density because it lowers circulating estrogen levels. (2) May increase total cholesterol levels (3) READ THE CARD FOR MORE Counseling: Talk to your PCP if marked weakness, drowsiness, pain or swelling of legs, blurred vision, or SOB occur. Monitor: BMD, Lipid panel
Methotrexate	Brand: Trexail Sig: 10 - 25 mg per week until adequate response is achieved Counseling: (1) Preferably taken on an empty stomach. (2) READ THE CARD FOR A LOT MORE) Monitor: CBC, Scr, LFT, Chest Radiograph
Metoclopramide HCl [Beer List]	Brand: Reglan Sig: 5 - 10 mg taken 30 mins b4 each meal and at bedtime for 2 - 8 wks. Counseling: Shd be taken 30 mins before meal
Ondansetron	Brand: Zofran, Zuplenz Sig: 8 mg TID Counseling: Do not remove chewable tabs from the blister until just prior to use. Do not try to push the tablet through the foil, peel the blister apart to remove.
Promethazine	Brand: Phenergan Sig: 12.5 - 25 mg Q4-6h PRN DDI: Anticholinergic may decrease effects

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