2. Basic cells and Chemistry

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5 HAP 1 Fichas sobre 2. Basic cells and Chemistry, creado por Jonathan Cash el 28/07/2015.
Jonathan Cash
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Jonathan Cash
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Nucleus • Every cell has one (well, almost every cell) • Contains chromatin = DNA = genetic material surrounded by an envelope • It directs cell activities = cell division & protein manufacture
Plasma Membrane • External boundary • Regulates entry & exit = selectively permeable • Double phospholipid layer with proteins
Cytoplasm = cytosol + organelles + cytoskeleton
Mitochondria Make ATP (adenosine triphosphate - cell energy) ADP + P = ATP (energy) Number α to energy requirements
Ribosomes • Small granules • Found free & attached to endoplasmic reticulum • follow genetic instructions for protein synthesis during protein manufacture
Endoplasmic Reticulum 2 types Rough ER Smooth ER
Golgi Apparatus • Modifies & packages proteins for external or internal use. - become part of the cell - be secreted from the cell - remain inside the cell • End product leaves in vesicles
Lysosomes contain lysozymes & other digestive enzymes
Cytoskeleton Dense support scaffold of filaments & cylinders for transport & shape.  Made of protein strands called actin and myosin
Active transport (Membranes) Requires Energy (ATP) e.g. sodium /potassium pump
Passive Transport list 4 Diffusion, Osmosis, Filtration, Facilitated diffusion
What is Diffusion Movement of molecules from area of high to low concentration or pressure using kinetic energy
What is Facilitated diffusion membrane proteins assit movement
What is Osmosis water moves through protein if there is a concentration difference
What is filtration Allowing fluid to surround the body’s cells and keeping large molecules from getting into the tissue fluid
Enzymes Act as catalysts in chemical reactions
Cations A positively charged ion
Neutrons Sub atomic particle with a neutral charge
Chemical Bond When electrons interact and form an energy relationship between atoms
Ions An atom that has lost or gained an electron
Anions A negatively charged ion
Electron Sub atomic particle with a negative charge
Matter A solid, liquid or gas that has mass and occupies space
Inorganic Compound A small, simple molecule without carbon
Salts Ionic compounds that split into particles when dissolved in water
Electrolytes When put into a solution these will break down into ions and are capable of conduction an electrical charge
Proton Sub atomic particle with a positive charge
Organic compound Large, bonded molecules that contain carbon
Atoms The smallest unit of an element that retains the properties of that element
What is a Cell = Cyte • Basic structural unit, • Smallest unit of life. • Contain organelles = little organs • Come in a variety of shapes & sizes
How do Phospholipids arrange themselves water-loving (hydrophilic) end is outwards & their water-hating (hydrophobic) end is inwards, creating an oily film
What makes up a Plasma Membrane? Phospholipids, cholesterol, sugars & proteins.
Cell membrane May be folded to form microvilli. • Increases cell surface area on free edge • Sometimes referred to as the brush border May have cilia for movement Outside surface is the glycocalyx
Cell membrane proteins • Receptors; for messenger molecules like neurotransmitters & hormones • Channels; allow water & substances through & act as gates • Transporters; pumping things in or out of cell
Cell membrane Proteins act as • Identity markers; identifying cells as yours. • Motor molecules; enable cilia to beat, white cells to move & flagella to whip • Cytoskeleton anchors organelles to membrane • Allow cells to stick together
Cholesterol • Gives support • Wedged between some of the tails
Membrane carbohydrates Attached to outer surface proteins -> glycoproteins Attached to membrane lipids -> glycolipids collectively called the blood group antigens receptors cell interactions
Inside the nucleus • full of chromatin • 46 chromosomes • Each chromosome contains about 4000 genes
Rough endoplasmic reticulum Rough ER. Branching channels studded with ribosomes. Transport & makes proteins & phospholipids. 84
Smooth Endoplasmic reticulum Branching channels. Makes, transports & stores lipids. Site of chemical reactions. e.g. glycogen to glucose. Detoxifies.
Vesicles transport bubbles
Centrioles 2, used in cell division. Surrounded by a clear area = centrosome
Vesicular transport Exocytosis: Moving substances out of the cell Endocytosis: Moving substances into the cell Phagocytosis: A type of endocytosis
Elements A large collection of the same type of atom • Listed in the periodic table
Elements How Many Natural Body • There are 105 listed • 92 are naturally occurring • 95% of the body uses just 4 elements
Kinds of matter - Mixtures 2 or more elements mixed together but retaining their individual properties. • Eg salt mixed into water • Can be physically separated out
Kinds of matter - Compound 2 or more elements bonded together • Individual properties lost • Compound has its own properties • Can’t restore compound to its elemental form. • Eg water (a liquid), made of 2 gases (H&O)
Major electrolytes
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