Pregunta | Respuesta |
what is pharmacology? | study of effects of drugs on the nervous system & behaviour |
what are drug effects? | when drugs introduce a change in a person's physiological processes & behaviour, typically with synaptic transmission |
what are the two types of drug effects | agonist & antagonist |
whata re the different types of sites of action? | production of NT effects of receptors effects on reuptake storage & release of NT |
what is the most !! & complex site of action? | effects of receptors |
how do drugs bind to the receptors? | direct -- activate receptor in place of NT indirect -- does not interfere with principal NT but stoll binds to receptor |
what is another name for direct binding & indirect? | competitive & noncompetitve respectively |
what is reuptake & how is it achieved | process of termination of the postsynaptic potential - taking back NT in cleft - destroying NT by enzyme |
what is aplacebo | inert substance given in place of a physiologically active drug |
what are placebo & nocebo effects? | placebo: ensure behavioural effects are caused by drug by giving this to control group nocebo: when people feel worse after an intervention when they should have no ill effects |
what are the two types of effects of NT? | excitatory (EPSP) inhibitory (IPSP) |
where are NT secreted from? | terminal buttons |
which is the most released NT from the efferent motor neurons? in the CNS | acetylcholine |
(learn that one table ot the NT's actions & receptors) | blah |
what is acetylcholine involved in | REM sleep, dreaming, perceptual learning, memory |
what are the two types of cholinergic synapses? | nicotinic & muscarinic |
what are nicotinic receptors like? | ionotropic, stimulated by nicotine, blocked by curare found on postsynaptic membranes of all autonomic ganglia, neuromuscular junction & some CNS pathways |
what are muscarinic receptors like? | metabotropic, produce parasympathetic nerve effects in the heart, smooth muscles, & gland stimulated by muscarine & blocked by atrophine |
how do the botox toxin & black widow spider venom affect the cholinergic synpases? | botox - antagonist venom - agonist, convulsions |
what are the 4 monoamine NTs? | dopamine, epinephrine, norepinephrine, serotonin |
the rest are... from the notes I guess, they're all messy & I'm tired |
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