Creado por Valentina Valenz
hace más de 8 años
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Pregunta | Respuesta |
ANTIBACTERIAL | a synthetic or natural agent that kills bacteria |
ANTIBIOTIC | naturally occurring antibacterial (penicillin) |
BACTERICIDAL | an antibiotic that kill bacteria |
BACTERIOSTATIC | an antibiotic that stops the growth of bacteria |
CHEMOTHERAPY | use of chemicals that can directly affect microorganisms at concentrations that are tolerable to the host |
CHEMOTHERAPEUTIC AGENTS | selectively toxic to parasitic organisms which invade the body |
IN VITRO | biological process that can be made to occur outside the body |
IN VIVO | biological process that occurs inside the body |
AGONIST | substance that interacts with specific cellular constituent and elicits an observable response |
ANTAGONIST | inhibits the effect of an agonist but no biological activity |
THERAPEUTIC INDEX (definition) | how much can be given to cure the patient/chemotherapeutic index (ideally > 1) |
THERAPEUTIC INDEX (formula) | Lethal Dose for 50% of patients ---------------------------------------------------------- Effective Dose for 50% of patients |
CHEMOTHERAPEUTIC INDEX | minimum curative dose ---------------------------------------------------------- maximum tolerate dose |
PRODRUG | a molecule that is inactive by itself, however transforms once it has an interaction with an enzyme and thus becomes active in the body |
DRUG STABILITY | can increase in vivo stability and prolong action OR can decrease in vivo stability and prevent potential toxicity |
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