Research into the relationship between the immune system and stress related illness

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1 During the chronic stress response a hormone called cortisol is released which prevents the growth of natural killer cells; an antibody which helps to fight off infection.
2 This suggests that people suffering with stress are more likely to become poorly.
3 Research which supports this assumption was conducted by Kiecolt-Glaser. This was a natural experiment where blood samples were taken from 75 medical students 1 month before exams and during exams.
4 Immune function was assessed by measuring Natural killer cell activity. She then correlated the results of these two sets of data.
5 NK levels were significantly reduced in the blood sample taken during exams. This suggests that stress does weaken the immune system leaving people vulnerable to illness.
6 One limitation of this research is that it only shows a correlation between stress and the level of natural killer cells, not cause and effect.
7 This means that other factors, such as the lifestyle of students may have been a contributing factor towards have a weaker immune system.
8 This research therefore only provides limited support for the relationship between the immune system and stress related illness.
9 Another limitation is that a bias sample was used; the participants were all medical students
10 People training to be doctors are unique in the sense that they will be in close proximity to ill people and possible as a result more prone to catching infections
11 For this reason the results cannot be generalised to the rest of the population.
12 In contrast another study found that stress actually enhances the immune system. However, these studies may not be comparable because they measured stress differently
13 The Yerkes Dodson curve could be offered as an alternative explanation;
14 this curve would suggest that there is an optimal level of stress, and if you have too much or too little stress your immune system will be weakened.
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