Lecture 2: Neurons and Glia

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Taken from Lecture 2 of PSY 314
McKenzie Sanders
Fichas por McKenzie Sanders, actualizado hace más de 1 año
McKenzie Sanders
Creado por McKenzie Sanders hace alrededor de 8 años
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What are the 2 divisions of the CNS? Brain and spinal cord
What are the 2 divisions of the PNS? Somatic and autonomic
What is the soma? What is its function? Cell body Protein production
What are dendrites attached to? What is their function? Attached to soma Function: receives information from terminal buttons of other neurons (input)
What is the axon attached to at each end? Soma & terminal buttons
What is the function of myelin? Myelin is a fatty substance that covers and insulates the axon
What are the terminal buttons attached to? What is their function? Attached to the end of an axon branch Function: forms synapse with another neuron (output)
What is a synapse? The junction between the terminal button and another neuronal membrane
What is the direction of messages in a neuron? Enters at dendrites, goes through soma down to initial segment of axon, leaves at terminal buttons
What are the 3 types of neurons? How do they differ? Unipolar neuron: Leaves the soma and divides into 2 branches Bipolar neuron: One axon and one dendritic tree at opposite ends of the soma Multipolar neuron: One axon and many dendritic trees
What type of neuron is the "typical" neuron? Multipolar neuron
What is axoplasmic transport? What makes it "active"? The process by which substances are transported up and down the axon. "Active" because it requires ATP & uses energy
What is anterograde axoplasmic transport? Moves away from the cell body to the terminal buttons
Which protein is involved in anterograde axoplasmic transport? Is it fast or slow? Kinesin Fast
What is retrograde axoplasmic transport? Moves towards the cell body
Which protein is involved in retrograde axoplasmic transport? Is it fast or slow? Dynein Slow
What are the basic functions of glia? Provide physical and chemical buffers to isolate neurons Surround neurons and hold them in place Control the supply of chemicals Insulate neurons from each other to keep signals apart Destroying and removing dead cells
What are the 4 types of glia? Astrocytes Oligodendrocytes Microglia Schwann cells
What are the functions of astrocytes? Physical support Clean up debris (phagocytosis) Produce chemicals Aid in controlling extracellular chemical environment Providing nourishment BBB Control blood flow Surrounding and isolating synapses
What are the functions of oligodendrocytes? Providing support to axons Producing myelin sheath Nodes of Ranvier
Are oligodendrocytes continuous or segmented? Segmented
What are the functions of microglia? Phagocytes: breaking down dead and dying neurons Immune system in the brain Protecting brain from microorganisms Inflammatory response to brain damage
What is the function of Schwann cells? Provide myelination in the PNS Providing myelin for a single axon or part of a single axon Can guide regrowth in case of axon damage
How many Schwann cells per segment? One
Where is the only place that Schwann cells are found? PNS
What is the function of the BBB? Regulating composition of extracellular fluid
What molecule is actively transported across the BBB? Glucose
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