Ruminant Digestion and Salivary Secretion

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Animal Disease 1 Veterinary Medicine Fichas sobre Ruminant Digestion and Salivary Secretion, creado por Louise Mason el 06/03/2017.
Louise Mason
Fichas por Louise Mason, actualizado hace más de 1 año
Louise Mason
Creado por Louise Mason hace más de 7 años
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What are the stomachs like in young ruminants? well-developed abomasum and immature forestomachs
What is the purpose of the reticular groove reflex? enables milk to bypass the rumen and enter the abomasum directly
Why is there an interest in preserving the reticular groove reflex in adult ruminants? Commercial interest to allow food supplements or medicine to bypass the rumen
What is the problem with only feeding young ruminants once or twice a day? may gorge when fed, and the excess ingested milk can 'leak' into the rumen
What is the problem with milk entering the rumen of young ruminants? the lactose is broken down into lactic acid, which lowers the pH of the rumen and affects the growth of a developing microflora population
In the adult ruminant, what becomes the dominant input for stimulating the reticular groove reflex? Pavlovian conditioning with associations with events preceding the presentation of milk
What part of the brain is responsible for controlling the reticular groove reflex? Medulla
What can send signals to the Medulla to bring about the reticular groove reflex? Milk in pharynx/chemo receptors (via afferent fibres) and the vago-vagal reflex (via efferent fibres)
What stimulates the growth of forestomachs? abrasive/churning action of forage particles and the chemical effects of fermentation products e.g. butyric acid
What percentage of gross energy in the ruminant comes from carbohydrates? 85%
Ruminants can break down all carbohydrates except for those bound to or masked by which molecule? Lignin
What bond is hydrolysed in ruminants that can't be hydrolysed in other mammals? Beta-bonded cellulose, hemicellulose and pectin
How are beta-bonds hydrolysed in the ruminant? hydrolysed by anaerobic microbes by fermentation
In ruminants, what are the products of carbohydrate digestion? Volatile Fatty Acids: acetate, propionate, butyrate
What effect does a high-starch diet have on VFA in ruminants? VFA are produced much faster with a higher proportion of propionate to other acids
What are the only two paths by which glucose can be produced in ruminants? from propionate: formed from OAA via succinate or formed via lactic acid when too much feed has been ingested
What three key factors influence fermentation? Substrates (carbohydrates, lipids, proteins), Microbes (substrate preferences and tolerance to conditions), Conditions (pH and substrate conditions)
Why does pyruvate produce VFA in ruminants but not in other mammals? there is no TCA in ruminants (entirely anaerobic)
What is the importance of producing Methane during carbohydrate fermentation? regenerates NAD+ from NADH
What does the diet determine in terms of rumen ecology? number of microorganisms and the balance between different types of them
How does a change in diet affect fermentation? alters the substrates which leads to a change in balance of microbes, also alters the conditions including end products and pH
How are some end products recycled within fermentation? they can act as substrates for other microbes (inter-dependency)
How is the production of VFA different as a result of protein digestion as opposed to carbohydrates? VFA are still produced but some differ by having branched carbon chains
What percentage of available energy from fermentation is used by the microbes themselves? 7%
In a high cereal diet, fermentation is mainly driven by which type of factors? post-absorptive factors, VFA in blood and sensory output from the liver (picked up in bloodstream as products of digestion)
In a normal/high roughage diet, what is fermentation mainly driven by? pre-absorptive factors, rumen volume
Why is it important in young ruminants that fermentation is driven mainly by pre-absorptive factors? they have a small, underdeveloped rumen which has a limited capacity for digestion. post-absorptive factors would be too slow to stop eating
Why is retention time important? digesting fibre-containing feed is time-consuming and so a long retention time is needed to fully break it down and absorb nutrients
What effect does increasing the amount of food fed have on the amount of energy extracted from it? available energy decreases as the food moves through the gut more quickly and so there is less time for energy to be absorbed
What are the functions of salivary secretion? oral hygiene and food lubricaiton
In the ruminant, why does saliva contain anti-frothing proteins? many plants have foaming agents and so specific enzymes are needed to break these down
In ruminants, why does saliva contain wetting agents? grass is protected by a layer of air that makes it hard to break down, so these proteins allow contact with grass to reduce the grass/air cohesion (gets grass wet)
In ruminants, why is saliva needed as a fluid? acts as a replacement of fluid, as it's the only source of fluid that isn't dietary based
What does the consistency of saliva depend on? depends on which salivary gland had the largest stimulation
What, in the ruminant, is dependent upon CNS control? salivary secretion and stomach motility
How does primary salivary secretion compare to ECF? always isomotic with ECF due to effective osmosis
What is saliva derived from and what effect does this have on blood flow? derived from plasma and so blood flow to acini is highly regulated
In monogastrics, what alters salt composition? duct cells to create saliva that is hypotonic and with low Sodium concentrations
In ruminants, what is different about the action of the Na+/K+ coupled transporter in ducts? only operative with Aldosterone - have to excrete excess dietary K+ into alimentary canal and retrieve Na+ from saliva
Approximately what percentage of body water is recycled throughout the GI tract every day? 50%
In ruminants, what is the main stimulus for salivary secretion? food in mouth and anticipation
What nerves control salivary secretion in ruminants? parotid and sublingual nerves (never zero as there's quite a high basal secretion)
How is saliva important as pH buffer in ruminants? neutralises 1/3 of acid in forestomach, bicarbonate and phosphate at high concentrations
What is the pH of ruminant saliva? around pH 8
What is the importance of phosphate ions in ruminant saliva? needed for the buffering effect and microbial growth
What is the importance of saliva as a source of Nitrogen in ruminants? Urea 'recycling' : urea diffuses from blood into saliva to be used for protein synthesis in reticulorumen when dietary protein is too low
How does eating rate vary with food water content? dry = slow wet = fast
What effect does parasympathetic innervation have on saliva secretion? increases salivary secretion with a watery content
What effect does sympathetic innervation have on saliva secretion? increases the secretion of viscous saliva
In what way does sympathetic control of saliva secretion work? noradrenaline-induced contraction of smooth muscles around acini and small ducts & increased protein synthesis in acini epithelial cells
What effect does parasympathetic innervation have on blood flow? increases blood flow to a larger extent than when exercising
What two types of long reflexes can increase the rate of saliva secretion? Inborn reflexes and conditioned reflexes
What are inborn reflexes? taste/smell sensory cells, mechanosensitive sensory cells in mouth, oesophagus and reticulorumen and chemosensitive cells in ruminant forestomachs
How are conditioned reflexes created? created when certain sensory stimuli are repetitively combined with feeding
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