Control of Gene Expression

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DNA and the Genome
Jade Lindsay
Fichas por Jade Lindsay, actualizado hace más de 1 año
Jade Lindsay
Creado por Jade Lindsay hace más de 7 años
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What is the Genotype of an Organism? The alleles Present
What is the Phenotype of an organism? The appearance of an organism
What is Intracellular? Something occurring or located inside a cell
What is Extracellular? Something occurring or located outside a cell
What does coding DNA produce? Proteins
What is Non-coding DNA involved in? Gene Expression
What are proteins? Polypeptide chains of amino acids held together by peptide bonds
Functions of Proteins -Structural components of Cell -Enzymes increase rate Chemical reaction -Hormones involved in regulation -Antibodies Give immunity against specific proteins
state the differences between DNA and RNA DNA- found in the nucleus ,two strands, deoxyribose sugarn Adinine Paired to Thymine RNA- Found in Nucleus and cytoplasm, one strand, ribose sugar, Adinine paired to Uracil
What are the three types of RNA? - mRNA (Messenger) -tRNA (Transport/transfer) -rRNA (Ribosomal)
State the location and function of mRNA Location - Nucleus and Cytoplasm Function - Carries a complementary copy of the genetic code from the DNA to the Ribosomes in the cytoplasm
State the location and function of tRNA Location- Cytoplasm and Ribosome Function- Carries specific amino acids to the Ribosome to be assembled into poly peptide chains
State the location and the function of rRNA Location- Ribosome Function- combined with proteins to make up the structure of ribosomes and takes part in translation of mRNA to amino acids
What is Transcription? The first stage of protein synthesis, takes place in the nucleus
Explain the Process of Transcription 1. A section of DNA uncoils 2. RNA nucleotides pair up with DNA nucleotides 3. A strand of primary mRNA is released (primary transcript) 4. RNA splicing converts primary transcript to mature transcript
Explain the process of RNA splicing 1.RNA splicing removes non-coding sections of DNA called Introns 2. Joins together the coding sections of DNA called Exons
What is Translation? The second and final stage of Protein synthesis
Explain the Process of Translation 1. A tRNA carries amino acids to their specific anti-codons where they pair with their codon 2. Peptide bonds join the amino acids on the tRNA 3. The first tRNA is released and the ribosome moves along a codon 4. Process is repeated
What is meant by the term ' one gene, many proteins' ? Different proteins can be expressed from the same gene due to alternative RNA splicing and various Post- translational modifications that can occur
What is Post- translational modification? Changes made to polypeptids following translation e.g adding on phosphate groups can change forms)
What is alternative splicing? Allows a primary transcript to form different mRNA molecules depending on which exons are included in the mature mRNA
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