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Descripción

VIRUSES
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Resumen del Recurso

Pregunta Respuesta
What is a virus? DNA or RNA that is protected by a protein coat
What is the general size of viruses? 25-300nm
What do viruses consist of? RNA, DNA or both (latter double- or single-stranded) and 5-200 proteins
What is the extracellular form of viruses called? Virion
What is the intracellular form of viruses? Replication of DNA/RNA and proteins; assembly of virus
What do viruses infect? Animals, plants, fungi and bacteria
Viruses that infect bacteria are called? Phages
Are viruses alive? No, they do not have metabolic activity
What is the protein coat of a virus called? The Capsid
What does the Capsid contain? A few proteins (Capsomers) that self assemble
What is the role of the Capsid? (2) Protects the RNA/DNA of the virus Determines the shape of the virus particle
Name the 3 types of viruses Naked Virus Enveloped Virus Complex Virus
What does the naked virus contain? -Protein Coat (Capsid) -Nucleic Acid (RNA or DNA) -Enzymes (E.g. Lysozyme, Reverse Transcriptase;not always)
Give an example of a naked virus Adenoviruses
What do enveloped viruses contain? -Protein coat (capsid) -Nucleic acid (RNA or DNA) -Enzymes (e.g. Lysozyme, reverse transcriptase, protease) -Biomembrane (lipids from host cell) -Envelope proteins (from the virus)
Give an example of an enveloped virus HIV
What do complex viruses contain? -Protein coat (Capsid) -Nucleic Acids (RNA or DNA) -Enzymes (e.g. Lysozyme, reverse transcriptase, protease) -Complex Protein Tail
Give an example of a complex virus T4 Phage
Name the 3 ways of which a virus can enter a host cell Endocytosis (triggers Clathrin-mediate) Membrane fusion Injection
Describe the structure of a bacteriophage Head Tail (Contractile sheet, tail fibres and base plate)
Describe the life cycle of a bacteriophage (6) 1. Attachment to the host cell 2. Injection of RNA or DNA 3. Replication of the genetic material 4. Synthesis of coat and tail proteins 5. Assembly of virions in the host cell 6. Release of the virions after lysis of the cell
What 2 types of entry do enveloped viruses use? Endocytosis and Membrane Fusion
What type of entry can naked viruses use? Endocytosis
How does the virus travel long distances within the cell? Virus particles use intracellular machinery; motors bind to the virus containing vesicle and travels along microtubules
What does HIV lead to? Acquired Immunodeficiency syndrome (AIDS)
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