Creado por Bhavi Mistry
hace más de 11 años
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Pregunta | Respuesta |
B antagonists | Treatment of CV symptoms of hyperthyroidism (decreases BP and HR) |
Radio iodine (131 I-) | Concentration in thyroid gland (destroys follicle cells) NOT associated with risk of tumours NOT for use in Children/Pregnant women 2-3 weeks to take effect |
Tetracosactide | ACTH analogue hypoglucocorticoidism |
Hydrocortisone | Steroid Hypoglucocorticoidism |
Sermorelin | Growth hormone releasing factor analogue Treatment of too little GH |
Somatotropin | Replacement therapy for too little GH |
Octreotride, Lanperotride | Somatostatin inhibitors (somatostatin inhibits GH release from anterior pituitary somatotrophs) |
Mechanism of action of theyroid hormone | Binds to TR and RXR which have a positive or negative effect on gene transcriptors (e.g. Increased contractility in the heart due to balance of myosin components - Gene expression regulated) |
Chemical causes of Hypothyroidism | Interferon exposure (from Hep B/C) - risk of autoimmune disorder Lithium (bipolar treatment) Amiloroderon - decreases Iodide intake by 37% |
Hypothyroidism diagnosis | Low T3 and T4 High TSH Tg Ab presence (autoantibody presence) Hyper cholesterolaemia as thyroid increase LDLR expression) |
Soloxinr (levothyroxine sodium, T4) | Given orally Standard replacement therapy for hypothyroidism |
Tetroxin (tri-iodothyronine, liothyronine, T3) | Hypothyroidism replacement therapy |
NI/KI | For iodide deficiency in hypothyroidism |
T3 metabolism | Max levels achieved in 1 day More potent |
T4 metabolism | Slow Max levels achieved at day 10 More prevalent |
Hyperthyroidism diagnosis | Symptoms Goitre/mass Increased T4 levels Decreased TSH levels |
Thiureylenes | Thyroperoxidase inhibitor Inhibits T3/4 secretion |
Thiureylenes | Thyroperoxidase inhibitor Inhibits T3/4 secretion |
Carbimazole | Thyroperoxidase inhibitor Inhibits T3/4 secretion |
High Iodide doses | Hyperthyroidism treatment Reduced T3/4 synthesis and release - used acutely |
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