Muscle disuse and atrophy

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Exersice Physiology Fichas sobre Muscle disuse and atrophy, creado por alexlpeart el 16/05/2013.
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Fichas por alexlpeart, actualizado hace más de 1 año
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Creado por alexlpeart hace alrededor de 11 años
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What is the protein turn over rate for man? 1.46% per day
Draw a graph to show how soon muscles begin to degrade after we stop using them. Draw on protein synthesis, protein degradation and mean protein gain or loss.
Describe the effects of immobilising a postural muscle. The EMG becomes phasic meaning fiber types turn from type IIx. type IIx is thought to be the unadapted state of muscles.
What happens to the muscle EMG when we immobilize the muscle? Reduced EMG activity
What happens to muscles when we immobilizes them in a shortened and lengthened state? Shortened muscle leads to atrophy as we lose sarcomeres. Lengthed leads to hypertrophy because we gain sarcomeres.
Describe how stretching a muscle while stimulating the muscle might change the results that we see. We see up to 30% increase in muscle mass in 4 days. Stretching alone might increased muscle protein synthesis.
when we immobilise muscles, _____ increases in the connective tissue, meaning the muscle is much _____ than before. Collagen, stiffer
Describe the effect of immobilization on enzyme activity in the muscle. slow muscles - decreased oxidative enzymes increased glycolytic enzymes Fast muscle - glyolytic enzymes decrease more than oxidative enzymes
Give some evidence that neural adaptions are lost more quickly than cross sectional area. When muscle undergoes atrophy due to lack of use, the CSA decreases by 8% but the max vol contraction falls by 24%. There must be something else decreasing max contraction, must be neural.
How can the degree of muscle atrophy be measured? weight muscle (animal studies only), Anthropometry (skin calipers), scanner such as MRI, DEXA, NMRI, CAT scan, MRT.
How long does it take for protein synthesis and degradation rates to change after exercise? Hours
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