Creado por Candice Young
hace más de 7 años
|
||
Pregunta | Respuesta |
End result of spermatogenesis | four non-identical sperm cells produced |
End result of oogenesis | 1 large ovum produced and 3 non-functional polar bodies |
Fertilization | oocyte undergoes meiosis, sperm cell fuses with ovum to form a zygote |
Cleavage | lots of RAPID cell divisions in zygote, very little growth or transcription, reduction of cytoplasmic volume, axes form |
Blastula | hollow ball of cells resulting from cleavage |
Gastrulation | make 3 distinct "germ" layers (endoderm, mesoderm, ectoderm) in Blastula, results in primitive gut formation |
Gastrula | 3 layered embryo |
ectoderm | forms nervous system and outer layers of skin |
endoderm | forms digestive tract. respiratory tract, and digestive organs |
mesoderm | forms kidneys, heart, muscles, bones |
Animal pole vs vegetal pole | Animal pole divides faster; dark brown coloring in Xenopus laevis; later are the ectoderm axis |
Cell movements during gastrulation | a lo of cells rush in from the outside and the rest spread themselves out (epiboly) thinly in an stretched out layer |
Molecular basis of gastrulation | changes in cell adhesion |
fate maps | tracking cells in time and space; show where each tissues of germ layer originally came from; do NOT inform us about when states of cell determination occur |
Roux's experiment | experimented by killing one frog blastomere cell at two cell-stage and observing the other's development concluded that blastomeres at the earliest stage have a predetermined fate and only a half embryo can form |
Driesch's experiment | separated sea urchin cells at two-cell stage and observed growth of a small but otherwise normal larvae revealed that at two (and four) cell stages, individual blastomeres are totipotent |
totipotency | the capacity for a cell to give rise to any embryonic cell type |
Horstadius' tier experiments | separate cells at 8 cell stage --> get a ciliated blastula and a vegetalized blob reveals how cells lose totipotency and become committed to a developmental fate as development proceeds |
John Gurdon's experiments | take adult frog skin cell and tadpole gut epithelial cell, destroy nuclei, and transfer nucleus into unfertilized eggs --> tadpoles develop shows that genetic information is not lost as cells differentiate |
Regulative Development Model | early embryos have a capacity for regulation; have developmental plasticity |
Asymmetric Division | Sister cells can be born differently despite having the same genetic information |
Symmetric Division | Sister cells with the same genetic information become different as a result of different neighbors acting on them |
How do cells know which genes to express? | the combination of internal information from asymmetrical distribution & external information from cell-cell signaling |
How animal-vegetal axis is determined (in Xenopus) | Determined maternally; egg radially symmetric before fertilization & there is differential localization of maternal mRNAs |
How dorsal ventral axis is determined (in Xenopus) | determined by where the sperm enters --> makes the cortex rotate 30 degrees |
Induction | cell-cell interactions cause special tissues to develop |
Spemann's separation experiment | divided two cells with a baby hair, one half could grow own embryo BUT plane of division is crucial |
The Organizer | cluster of cells in developing amphibian embryo that induce development of central nervous system; crucial discovery to concept of induction |
dorsal lip of the blastopore | cells that are COMMITTED to invaginate into the blastula, "the Spemann organizer," formed by the gray crescent region of an egg |
Results of dorsal lip transplant | continued to be committed to its "fate" --> initiated a second gastrulation in surrounding tissue and two embryos/axes form via induction |
B-catenin | protein that can induce changes in cell fates based on where it accumulates; can form new dorsal regions when injected |
Specification | when the mesoderm is under the ectoderm, tissue is specified to become the nervous system BUT if moved it could become something else NOT irreversible! |
Determination | when cells will produce the determined cell types and will not be altered by inducers to become completely different IRREVERSIBLE |
Involuting Marginal Zone cells | on the dorsal lip of the blastopore in developing Xenopus eggs, move to the interior via invagination and become the mesoderm |
Neurula | What the embryo is called after gastrulation leads to the formation of the neural fold --> notochord |
What's in a human sperm cell? | Haploid nucleus, centriole (forms spindles during division), mitochondria, acrosome enzymes (to digest egg coat) |
What's in a human egg cell? | Egg cytoplasm: nutritive proteins, ribosomes & tRNA, **mRNAs**, morphogenetic factors, protective chemicals, egg cortex (cortical granules) Vitelline membrane to attract and activate sperm + regulate ion flow |
Egg-sperm recognition | Exocytosis of sperm's acrosomal vesicle, bindin coats sperm actin filaments and binds sperm to vitelline envelope, sperm passes through and membranes fuse |
Fast block to polyspermy | Depolarization of egg electric potential due to influx of Na+ means no more sperm can fuse |
Slow block to polyspermy | cortical granules cleave links between vitelline membrane and plasma membrane, stimulated by increase in intracellular Ca2+ from sperm fusion |
Follicle Stimulating Hormone (FSH) | produced by pituitary gland, controls production of oocytes in women and sperm in men; stimulates production of estrogen in women |
Corpus luteum | involved in production of progesterone, left behind after egg leaves in ovulation, maintains uterine lining (endometrium) |
Luteinizing hormone | hormone that triggers ovulation and development of corpus luteum |
where does fertilization (as well as the first cleavage) occur? | in the fallopian tube/OVIDUCT |
first ball of cells after cleavage in humans | the morula |
human chorionic gonadotrophin (hCG) | hormone secreted by specialized cells that maintains the corpus luteum after implantation |
Implantation | human blastula is implanted into endometrium, trophoblast outer layer forms placenta so direct nutrient exchange can occur |
chorionic gonadotropin | hormone secreted by trophoblast and chorion that maintains corpus luteum after implantation |
The Four Extra-embryonic Membranes | 1) Chorion 2) Amnion 3) Yolk Sac 4) Allantois |
Chorion | trophoblast, surrounds everything |
Amnion | cushions embryo and prevents desiccation; is fluid filled |
Yolk sac | forms blood cells that migrate into the embryo, doesn't actually contain yolk |
Allantois | develops from archenteron (gut) outgrowth, becomes a part of the umbilical cord |
First Trimester | three germ layers --> limb buds --> developed enough to be called an embryo (non-self) --> limb elongation --> organs are in place --> hCG levels drop and CL begins to disentegrate |
Second Trimester | progesterone production --> general growth --> bone development --> heart beating --> vernix (skin) covering |
Third trimester | weight increase --> eyelids split --> lungs mature --> hearing develops --> uterine cavity full |
¿Quieres crear tus propias Fichas gratiscon GoConqr? Más información.