Pharmaceutical forms

Descripción

mapa para el lunes.
Alan Zurita Aguilar
Mapa Mental por Alan Zurita Aguilar, actualizado hace más de 1 año
Alan Zurita Aguilar
Creado por Alan Zurita Aguilar hace más de 7 años
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Resumen del Recurso

Pharmaceutical forms
  1. Oral solid:
    1. Tablets
      1. capsule
        1. FFLM
          1. Granules
            1. Oral Liquids
              1. Syrup
                1. Elixir
                  1. Suspension
                    1. Fluid emulsions
                      1. Herbal tisanas
                        1. DISADVANTAGES
                          1. Increased microbiological contamination (addition of preservatives). Higher stability of the active principle.
                2. ADVANTAGES
                  1. Quickly release active substance: high BD in speed. -Easy and convenient dosing (tablespoons, drops) -Results of choice particularly in children.
                  2. Sublingual
                    1. The sublingual mucous is very vascularized: rapid absorption rate.
                      1. FF: tablets and aerosols.
                  3. Seals
                    1. They are capsules with a receptacle of starch
                    2. It can serve as an intermediate for obtaining tablets or filling capsules
                    3. Better dosage regimens, Best pharmacokinetic profile , Reduction of adverse effects.
                      1. They can not be split. Not suitable for patients with swallowing problems. Worst control in overdose situations
                    4. Good stability and bioavailability, easy processing
                      1. Higher cost, content limitations, do not work in patients with swallowing problems
                    5. low cost, Presicion dosing, Extend period of validity
                      1. Limited use in patients who can not swallow, problems of bioavailability.
                    6. Advantages
                      1. Disadvantages
                    7. Clasication
                      1. solids
                        1. Powder, granules, capsules, seals , tablets, suppositories, implants
                        2. semi-solids
                          1. ointments, creams and gels
                          2. Liquids
                            1. Solutions Suspensions Emulsions Syrups Elixirs Lotions Injectable Linings
                          3. Topical and subcutanea
                            1. Dermal
                              1. Aplicable on the skin
                                1. Advantage
                                  1. Disadavantage
                                    1. feel stcky
                                    2. Easy to apply , low cost and greater absortion
                                2. Ointments,
                                  1. creams
                                    1. gels
                                      1. pastes
                                        1. patches
                                          1. implants
                                  2. Transdermal
                                    1. Diffusion of the active principle to the skin surface
                                      1. Advantage
                                        1. Disadvantage
                                          1. Prevent degradation to gastric pH and its administration can be stopped immediately.
                                            1. low cost
                                          2. Transdesmal Patches
                                        2. Ophthalmic and Optics
                                          1. Types of pharmaceutical forms
                                            1. Eye drops, ointments, emulsions, ophthalmic inserts, drops.
                                            2. Advantage
                                              1. Disadavantage
                                                1. Maybe uncomfortable when applied.
                                                  1. Do not use if timpanic membrane is perforade
                                                2. Rapid Absorption, Local Action
                                                  1. Low cost
                                              2. Conventional release
                                                1. Modified release
                                                  1. Allow to reach a profile of plasma concentration that guarantees the persistence of the therapeutic action of the drug.
                                                  2. The release of the active principle is not deliberately modified by a particular formulation design
                                                  3. Parenteral
                                                    1. Extravascular
                                                      1. Intravascular
                                                        1. Intra-arterial
                                                          1. The effect of the drug can be localized in a given organ
                                                            1. Possibility of drug leakage to the general circulation
                                                          2. Intracardiac
                                                            1. Allows to act directly in the myocardium
                                                              1. Difficulty of technique
                                                            2. Intravenous
                                                              1. Quick effect
                                                                1. Poor circulation impairs drug delivery
                                                            3. Intradermal
                                                              1. Slow absorption (when allergy testing is performed)
                                                                1. Breaks the protective barrier of the skin
                                                                  1. Disadvantages
                                                                  2. Advantages
                                                                2. Intraperitoneal
                                                                  1. Ultrafast absorption
                                                                    1. Interferes with anticoagulants
                                                                  2. Intrathecal
                                                                    1. Epidural
                                                                      1. Give access to the Central Nervous System
                                                                        1. It is difficult to apply
                                                                      2. Intramuscular
                                                                        1. Fast route of administration
                                                                          1. Some drugs can irritate tissues and cause pain
                                                                        2. Subcantanea
                                                                          1. The onset of action is faster than the oral route
                                                                            1. More expensive
                                                                          2. Intraarticular
                                                                            1. Direct contact with the walls and joint tissue
                                                                              1. Unmanageable and painful
                                                                        3. Inhalation
                                                                          1. Aereosol Sprays
                                                                            1. Gases
                                                                              1. Gases and Volatile Liquids
                                                                                1. General anesthetics
                                                                                  1. Easily cross the blood-brain barrier
                                                                                  2. Medical oxygen
                                                                                    1. Application of pure oxygen
                                                                                      1. You need the use of more equipment
                                                                                    2. A larger fraction of the drug reaches the lung
                                                                                      1. Requires coordination between pulsation and inspiration
                                                                                        1. Disadvantages
                                                                                        2. Advantages
                                                                                      2. Nasal
                                                                                        1. Route of administration to the parenteral in those places whose oral administration is not possible
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