Cytoskeleton

Nota:

• A network of fibers extending throughout the cytoplasm, regulates cellular activities (ex. moving macromolecules).
• Keeps the cell together (structure) and insides components(organelles) in place ("anchor-age")

1. Motor proteins

   Nota:

   • Movement! Converting chemical energy into mechanical work (using ATP or proton pump).
   1. Different proteins

      Nota:

      • Has same job (transportation), But different motor proteins are transport/moving different substrates that are for different jobs. 
2. Vesicles

   Nota:

   • travel along "monorail" in cytoskeleton
3. Fibers of cytoskeleton
   1. Microtubules

      Nota:

      • Thickest
      1. Function

         Nota:

         • Guiding movement, Shaping cell, Separating chromos.in cell division
      2. Cilia + flagella

         Nota:

         • Basal body keeps them attached
         • Has dynein (motor protein) to get them moving along!
   2. Microfilaments

      Nota:

      • Thinnest, made of actin (a twisted rope shape motor protein), 
      • Bear tension, resisting pulling forces inside the cell
      1. Cortex

         Nota:

         • A bunch of microfilaments, inside plasma membrane, gives cell a shape.
      2. Function

         Nota:

         • Motor proteins: Myosin and actin get things moving along
      3. Muscle cells

         Nota:

         • A bunch of microfilaments
   3. Intermediate filaments

      Nota:

      • In-between size, Break it down --> stronger than microtubules
      1. Function

         Nota:

         • Give cell a shape and parks the organelles in a spot.
         • More permenant of the 3.