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1032183
Pharmacological Treatments for DYSPEPSIA, GASTRITIS & PEPTIC ULCER
Descripción
Diploma Pharmacology II Mapa Mental sobre Pharmacological Treatments for DYSPEPSIA, GASTRITIS & PEPTIC ULCER, creado por sesamemonstersx el 25/06/2014.
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pharmacology
pharmacology ii
diploma
Mapa Mental por
sesamemonstersx
, actualizado hace más de 1 año
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Pharmacological Treatments for DYSPEPSIA, GASTRITIS & PEPTIC ULCER
Acid Suppression
Histamine (H2) Receptor antagonist
MOA: Inhibits the action of Histamine ay H2 receptor on Parietal Cells
Administration
Twice Daily
Single dose at night for 4-8 weeks
Side effects
Diarrhoea
Altered Liver Function Test
Headache
Dizziness
Rash
Tiredness
Proton Pump Inhibitor
MOA: Inhibit H+/K+ dependent ATPasse proton pump, degreasing gastric acid secretion
Better than H2 antagonist as H2 only inhibit Histamine component, PPI inhibit the proton Pump
Examples
Omepraozole
Esomeprazole
Side Effects
GI distrbances
Headache
DIzziness
Caution
Gastric Cancer
Liver disease
Pregnancy & breast feeding
Antacids
Types
Magnesium
Diarrhoea
Aluminium
Contipation
Calcium
Hypercalcemia
MOA: Neutralize Gastric Activity
Increase In stomach and duodenal pH
Inactivation of pepsin
Alginate-containing
Forms a raft that floats on the surface of the stomach content
Prokinetics
MOA: Dopamine antagonist
Stimulate gastric emptyping & small intestinal transit
Enhance strength of esophageal spinchter contration
Examples
Metoclopramide
Doperidone
Side Effects
High blood prolactin level
Enlargement of breast in male
Abnormal production of breast milk
Cytoprotectives
Chelates
Unknown MOA
Examples
Tripotassium Dicitratobismuthate
Rinitidine bismuth citrate
Misoprostol
Uses
Older Frail People
prevention of gastric ulcer in patients requiring long tern non-steroidal or aspirin therapy
MOA: Antisecretory, inhibit basal & noctonal gasric acid secretion by parietal cells
Complexes
Sucralfate
MOA: activated by acid, forms viscous adherent gel that bind to ulcer crater
inhibit pepsin, absorbs bile salts
Side effects
Constipation, diarrhoea
Nausea
Gastric Discomfort
H.pylori Eradication
Recommended regimen
Recursos multimedia adjuntos
H2_receptor_antagonist (image/jpg)
h_pylori_2 (image/png)
hpylori_1 (image/png)
h_pylori_3 (image/png)
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