1750-1900 the fight against smallpox: Jenner and vaccination
If you catch a disease, your body creates special cells
called antibodies to fight off the infection
and if you survive you may become immune to any further attacks of that disease
This idea led to a procedure called inoculation
1. A small amount of pus is taken from a sufferer's smallpox blister
2. It is spread into a small cut made between the thumb
and the forefinger of the person being innoculated
3. A mild version of smallpox develops; the person survives and is then immune to further attacks
HOWEVER, inoculation did not completely solve the problem of smallpox
Because not everyone could afford to have it done
and inoculation was not always effective or safe
Local people said they did not need to be inoculated
They claimed that if they had already had cowpox they would not catch smallpox
Jenner decided to check this idea...
Smallpox parties
Lady Mary Wortley Montagu (the wife of the British ambassador to Turkey)
She witnessed the inoculation in the early 18th century
She had nearly died from smallpox when she was younger
She was keen to protect her children - she had them inoculated in 1721
The idea of inoculations quickly became very popular in Britain
People would even have smallpox parties
Where they would all be inoculated together
Since doctors were paid for this, they could make a lot of money
Edward Jenner ( a doctor in Gloucestershire )
14 May 1796 - 'took some cowpox matter from a blister on the arm of
Sarah Nelmes and inserted it into two cuts made on James' arm'
'A week later he became chilly, lost his appetite and had a headache - but the next day he was completely well
inoculated him with smallpox but he was immune to it!
To make sure of his findings, he vaccinated 23 others including his 11 month old son
People were immune- he published his ideas giving the name 'Vaccination' to his new technique of inoculation with cowpox
Vacca is the Latin for cow
HOWEVER , the Royal Society refused to publish his account
He had to pay for his report to be printed himself.
He called this vaccination
In 1802 the British Government awarded Jenner £10,000 for his work
against smallpox - 5 years later they gave him an additional £20,000
Jenner's Work
The link only existed between smallpox and cowpox. It did not work for any other diseases
Jenner worked in a scientific way and did a number of tests
Jenner had pamphlets (like leaflets) printed for other scientists to
read: the pamphlets described his experiments very clearly so
that other scientists could check his work
Jenner did not mind other people using his ideas - he wanted lots of people to
benefit from his work
Vaccination showed that it was possible to prevent some people catching a disease
Jenner could not explain how the link between cowpox and smallpox worked
Vaccination was not always successful - and some people did
develop smallpox because some doctors did not carry out the
vaccination carefully enough
In 1802 the Jennarian Society was set up in London to promote vaccination and
within 2 years over 12,000 people had been vaccinated
The government provided a grant to pay for people to have free vaccinations,
As a result of this, doctors lost money because people no longer paid for inoculations
Therefore many doctors opposed Jenner's work
Napolean in France and president Jefferson in the USA both thought vaccination
was a great breakthrough
In 1852 the government made it COMPULSORY to be vaccinated
When the British government enforced compulsory vaccination in 1872
The number of smallpox cases dropped dramatically, and in 1979 the World Health Organization announced that smallpox had been wiped out completely