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155266
The Liver
Descripción
Biology
Sin etiquetas
a2
biology
biology
a level
Mapa Mental por
e.smith96
, actualizado hace más de 1 año
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Menos
Creado por
e.smith96
hace alrededor de 11 años
103
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Resumen del Recurso
The Liver
Structure of Liver
Blood Vesseks
Hepatic Vein
Hepatic Artery
Hepatic Portal Vein
Bile Duct
Inter-lobular vessels
Branches from the hepatic artery and hepatic vein enter
Sinusoid
Specialised capillary where blood from the hepatic artery and hepatic vein mix
Hepatocytes
Liver cells
Kupffer Cells
Gall Bladder
Ornithine Cycle
Ammonia + carbon dioxide------> urea + water
2NH3 +CO2------> CO(NH2) + H20
Diagram
Bile
Bile is secreted from the liver
Bile has a digestive and excretory function
The bile duct carries bile from the liver to the gall bladder where it is stored until needed
Kupffer Cells
They move out of the sinusoids breakdown and recycle old red blood cells
Specialist macrophages
One product is bilirubin which is excreted in the bile and gives the brown pigment in faeces
Blood Vessels
Hepatic Portal Vein
Deoxygenated and rich in products of digestion
Purpose
Brings toxins to the liver
Direction of flow
From intestines to liver
Hepatic Artery
Oxygenated Blood
Purpose
Supplies oxygen
Direction of flow
From heart to liver
Hepatic Vein
Deoxygenated Blood
Direction of flow
Liver to heart
Purpose
Returns blood to normal circulation
Deamination
The removal of the toxic amine group from an amino acid to produce a less toxic ammonia
Amino acid + O2 ------> Keto acid + ammonia
Formation of urea: ammonia + CO2 -------> urea + water
Ammonia is excreted as urea
Detoxifcation
Liver cells contain enzymes that make toxic molecules less toxic
Catalase which converts hydrogen peroxide to oxygen and water
Of Alcohol
Enzyme ethanol dehydrogenase
Ethanol to ethanal gives of NADH
Enzyme ethanol dehydrogenase
Converts ethanol to ethanoate gives of NADH
Ethanoate combines with coenzyme A
Forms actetyl coenzyme A
Cirrhosis
A chronic Liver disorder that is mainly found in alcoholics.
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