2557814
psychotropics
- psychosis means: loss of contact
with reality/delusional/schizo
- antipsychotics 1st and 2nd gene
- Chlorpromazine(Thorazine),
Haloperidol (Haldol) blocks
D2 receptors
- Aripiprazole (Abilify),
Quetiapine(Seroquel),
Risperiodone
(Risperdal)
- blocks D2 receptors and serotonin
- blocks D2 receptors and serotonin
- Chlorpromazine(Thorazine),
Haloperidol (Haldol) blocks
D2 receptors
- antipsychotics 1st and 2nd gene
- antidepressants
- tricyclic
antidep (tcas)
- elevates mood,
amitriptyline, blocks
nerepiephrine uptake and
serotonin uptake so that
more is available in the
brain
- adverse effects:
orthostatic hypotension,
sedation, dry mouth,
constipation, blurred
vision, seizures, hepatic
failure, leukopenia,
thrombocytopenia,
- adverse effects:
orthostatic hypotension,
sedation, dry mouth,
constipation, blurred
vision, seizures, hepatic
failure, leukopenia,
thrombocytopenia,
- elevates mood,
amitriptyline, blocks
nerepiephrine uptake and
serotonin uptake so that
more is available in the
brain
- selective serotonin
reuptake inhibitors (ssris)
- MOA: blocks serotonin
uptake--fluoxetine,
sertraline, paroxetine,
citalopram side effects: sex
dys, nausea, insomnia, do
not use with maois and
grapefruit juice
- MOA: blocks serotonin
uptake--fluoxetine,
sertraline, paroxetine,
citalopram side effects: sex
dys, nausea, insomnia, do
not use with maois and
grapefruit juice
- serotonin
norepinephrine
reuptake inhibitors (snris)
- Venlaflaxine (Effexor): side
effects--dry mouth, suicidal
tendency, urinary retention,
steven johnsons, cannot mix
with maois
- Venlaflaxine (Effexor): side
effects--dry mouth, suicidal
tendency, urinary retention,
steven johnsons, cannot mix
with maois
- monoamine
oxidase inhibitos
(maois)
- Isocarboxazid,
Phenelzine, Selegiline,
Tranylcypromine
- MOA: inactivates norepinephrine,
dopamine, epiephrine, serotonin
- only prescribed if other antidepr
do not work, as it puts pts at risk
for hypertensive crisis and cannot
eat --aged cheeses, yeast, fish,
meat, choc, some veggies, alcoholic
drinks, fruits, st johns wort, or
ginseng side effects: suicidal
tendencies
- only prescribed if other antidepr
do not work, as it puts pts at risk
for hypertensive crisis and cannot
eat --aged cheeses, yeast, fish,
meat, choc, some veggies, alcoholic
drinks, fruits, st johns wort, or
ginseng side effects: suicidal
tendencies
- MOA: inactivates norepinephrine,
dopamine, epiephrine, serotonin
- Isocarboxazid,
Phenelzine, Selegiline,
Tranylcypromine
- tricyclic
antidep (tcas)
- anti anxiety medications
- benzodiazepines: MOA:
enhances inhibiting effects
of GABA, rapid onset
- Alprazolam (xanax),
Chlordiazepoxide (Librium),
Clonazepam (Klonopin),
Clorazepate (Tranxilium),
Clotiazepam (Veratran),
Diazepam, Lorazepam,
Oxazepam
- side effects: also can be used to prevent seizures and alcohol
withdrawal--sedation, dizziness, ataxia, confusion, dry mouth, blurred vision,
orthostatic hypertension--od then respiratory depression
- side effects: also can be used to prevent seizures and alcohol
withdrawal--sedation, dizziness, ataxia, confusion, dry mouth, blurred vision,
orthostatic hypertension--od then respiratory depression
- Alprazolam (xanax),
Chlordiazepoxide (Librium),
Clonazepam (Klonopin),
Clorazepate (Tranxilium),
Clotiazepam (Veratran),
Diazepam, Lorazepam,
Oxazepam
- benzodiazepines: MOA:
enhances inhibiting effects
of GABA, rapid onset
- mood stabilizers
- bipolar disorders/manic
depressive disorders
- lithium- valproic acid, carbmazepine Adverse
reactions: sedation, dizziness, tremors, nausea,
vomiting, diarrhea, unsteadiness, headache, wt
gain, hematological changes--dry mouth,
increased urination, need hydration
- on lithium-monitor drug level due to narrow
therapeutic range,
- on lithium-monitor drug level due to narrow
therapeutic range,
- lithium- valproic acid, carbmazepine Adverse
reactions: sedation, dizziness, tremors, nausea,
vomiting, diarrhea, unsteadiness, headache, wt
gain, hematological changes--dry mouth,
increased urination, need hydration
- bipolar disorders/manic
depressive disorders
- ADD/ADHD -treats stimulants
-amphetamine, methylphenidates
- tachy, hypertension, wt loss, growth
slowed and sleep disturbed
- nonstimulant meds:
- antidepres/nortriptyline--clonidine
(a2 adrenergic antagonists)--side
effects termors, tachy,
hypertension, insomnia
- antidepres/nortriptyline--clonidine
(a2 adrenergic antagonists)--side
effects termors, tachy,
hypertension, insomnia
- tachy, hypertension, wt loss, growth
slowed and sleep disturbed
- sleep hypnotics
- clonazepam, diazepam,
diphenhydramine, doxylamine +
diphenhydramine, eszopiclone,
lorazepam, melatonin,
promethazine, triazolam, zaleplon,
zopidem
- withdrawal symptoms:
rebound anxiety, adverse
CNS depression
- zopidem (Ambien) side effects: risk for
delusions, hallucinations, short term use
one month
- zopidem (Ambien) side effects: risk for
delusions, hallucinations, short term use
one month
- withdrawal symptoms:
rebound anxiety, adverse
CNS depression
- clonazepam, diazepam,
diphenhydramine, doxylamine +
diphenhydramine, eszopiclone,
lorazepam, melatonin,
promethazine, triazolam, zaleplon,
zopidem
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