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Lung Disease
Descripción
Lung disease: pulmonary tuberculosis, pulmonary fibrosis, asthma and emphysema
Sin etiquetas
biology
aqa as
unit1
Mapa Mental por
LaraPartridge
, actualizado hace más de 1 año
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Creado por
LaraPartridge
hace más de 9 años
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Resumen del Recurso
Lung Disease
Pulmondary Tuberculosis
Transmission by droplet infection
Close contact
care homes
People who are from countries where Tb is common
Reduced Immunity
Course of Infection
Primary Infection (children)
Mycobacterium tuberculosis is inhaled
Bacteria grow and divide in upper region of lungs (lots of O2)
Phagocytes accumulate at infection to ingest mycobacterium tuberculosis
Immune response makes are inflamed and lymph nodes are enlarged
Post-primary infection (adults)
Some bacteria may remain from the primary infection and later re-emerge.
Occurs in the upper region of the lungs
The bacteria destroy the lung tissue
The body tries to repair lung tissue and makes scar tissue as a result.
Symptoms
Coughing up damaged tissue containing blood and bacteria
loss of appetite -) weight loss
Tiredness
Fever
Prevention and Control
Vaccination
BCG vaccine
Attenuated mycobacterium bovis
Social and Economic methods
Better education
more and better housing
Improved health facilities and treatments
Better nutrition to aid immune sytems
Drugs
Disadvantages
Resistance to drugs
Longs course (6-9 months)
Pulmonary Fibrosis
What is it?
Irreversible thickening of the lungs due to scar tissue
The diffusion pathway is lengthened
the diffusion of oxygen is less efficient, making ventilation difficult
The volume of the lungs is reduced
The elasticity of the lungs is reduced
Reducing the force of expulsion
Symptoms
Shortness of breath
Due to decreased volume
Due to increased length of diffusion pathway
Due to loss of elasticity making it hard to maintain a diffusion gradient
Chronic, dry cough
Due to the body's reflex reaction to fibrous tissue stuck in the airways
'Dry' because fibrous tissue is immovable.
Pain and discomfort in chest
Due to the pressure on fibrous tissue
Due to the damage
Weakness and fatigue
Due to a reduced intake of oxygen into the blood reducing the amount of energy produced by respiration
Asthma
What is it?
localised allergic reaction
Pollen, animal fur,dust mite faeces
White blood cells on the lining of the bronchi/bronchioles release histamine...
Histamine inflames the lining of airways
Histamine causes epithelial cells to secrete more mucus.
Histamine causes fluid to enter the airways
Histamine causes bronchiole muscle to contract, constricting the bronchiole
Overall, a greater resistance to the flow of air
It's hard to ventilate lungs, so hard to maintain a diffusion gradient
Genetic
Symptoms
Difficulty breathing
Due to constricted bronchi, excess mucus/fluid and inflamed linings
Wheezing when breathing
Due to air passing through constricted bronchi(oles)
Tight chest
Due to not being able to ventilate the lungs properly because of the constricted bronchi(oles)
Coughing
A reflex response to obstructed bronchi.
Emphysema
What is it?
induced by smoking
Can only be diagnosed once the lungs are irreversibly damaged
Elastin of lungs has been permanently stretched
Sufferer is no longer able to expel all of the air from the alveoli
The surface area of the alveoli is reduced and they can burst
Little gaseous exchange can take place
Symptoms
Shortness of breath
Due to difficulty exhaling air because of the reduced elasticity of the lungs and reduced surface area.
Chronic cough
Due to the body's effort to remove damaged tissue and mucus because the cilia have been destroyed.
Blue skin
Due to low levels of oxygen in the blood.
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