Connective tissue

Embryonic CNT
1. Mesenchyme
  1. **no fibers
  2. mesenchymal cells + ground substance
2. Gelatinous (mucous) CNT
  1. fibroblast + collagen fibers
  2. พบที่ hypodermis &umbilical cord
Adult CNT
1. Contain
  1. Cells
  2. Extra Cellular Matrix
    1. Fibers
      1. Collagen Fiber
        stretched for 5%
        PINK with H&E
        digest by collagenase, trypsin, pepsin
        type I - XVIII, I-IV are most common
        Boiled >> Gelatin
      2. Reticular fiber
        type III Collagen
        BLACK with Silver staining
      3. Elastic Fiber
        LIGHT PINK with H&E
        Consist of fibrillin&elastin
        Resistant to boiling,acids,alkalis
        Digested by enzyme elastase
    2. Ground Substance
      1. Glycoprotiens
        (more protien less carb[oligosacharide]
      2. Proteoglycans (สร้างโดย Fibroblast)
        more carb[glycosaminoglycan(GAGs)] less protien
        GAGs
        **Hyaluronan
        Chondroitin sulfate & dermatin sulfate
        Heparan sulfate & heparin
        Keratan sulfate
2. Loose CNT
  1. Fixed cells
    1. Fibroblast
    2. Pericyte (perivascular cell)
  2. Free cells
    1. Macrophage
      1. Multinucleated giant cell
      2. protective role
    2. Mast cell
      1. metachromatic granules
      2. รองเท้าแตะ
    3. Plasma cell
      1. cartwheel
      2. halo area
    4. Melanocyte
    5. WBC
3. Dense CNT
  1. irregular
    1. collagen fiber
    2. found in
      1. organ's capsule
      2. fasciae
      3. aponeuroses
      4. joint capsule
      5. pericardium
      6. dermis
  2. regular
    1. collagen tendons & ligaments
      1. joint
    2. Elastic ligaments
      1. Nuchal ligament (Trichrome stain)
        Elastic fiber
        Collagen fiber
        Nucleus
4. Reticular CNT
  1. Reticular cells (fibroblast) & reticular fiber
  2. framework in
    1. lymph organs
    2. lymphatic nodules
    3. bone marrow
  3. BLACK with Silver stain
5. Adipose tissue (fat)
  1. Brown
    1. multilocular
    2. round, centric nucleus
  2. White (Bad)
    1. flat, eccentric nucleus
    2. unilocullar

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	Creado por Chutikan Srisang hace alrededor de 9 años