341513
Parkinson's Disease
- Slowly progressing
neurologic movement
disorder d/t dopamine &
acetylcholine imbalance
- results from destruction of
pigmented neuronal cells in
substantia nigra in basal
ganglia
- results from destruction of
pigmented neuronal cells in
substantia nigra in basal
ganglia
- CM's - occur when 60% of
pigmented neurons lost &
dopamine level decr by 80%
- tremor, rigidity,
bradykinesia,
postural instability
- depression, dementia,
delirium, hallucinations
- tremor, rigidity,
bradykinesia,
postural instability
- Levodopa is
primary treatment,
other adjunctive
therapies used as
well
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