Control of gene expression in Prokaryotes

Descripción

Advanced Molecular Biology & Biotechnology Mapa Mental sobre Control of gene expression in Prokaryotes, creado por Abbey Roberts el 09/11/2013.
Abbey Roberts
Mapa Mental por Abbey Roberts, actualizado hace más de 1 año
Abbey Roberts
Creado por Abbey Roberts hace casi 11 años
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Resumen del Recurso

Control of gene expression in Prokaryotes
  1. Enzymes
    1. Inducible
      1. Constitutive
        1. Repressible
        2. Regulation control
          1. Positive
            1. Negative
            2. Regulatory elements
              1. Cis-acting
                1. Trans-acting
                2. Lac operon
                  1. Structural genes
                    1. lacZ
                      1. lacY
                        1. lacA
                        2. Negative control
                          1. Transcription only occurs when the repressor fails to bind to the operator region
                          2. Model
                            1. Proved by analysis of lac expression in the absence or presence of lactose in partial diploid merozygotes
                          3. Catabolite activating protein
                            1. Involved in catabolite repression
                              1. repress expression of the lac operon when glucose is present
                              2. In the absence of glucose and presence of lactose, CAP exerts positive control
                                1. binding the CAP-binding site and facilitating RNA polymerase binding at the promoter
                                2. Cyclic adenosine monophosphate is required for CAP binding
                                  1. Glucose represses expression of adenylyl cyclase
                                    1. the enzyme that catalyses the production of the trp structural genes
                                3. Trp operon
                                  1. Transcription can occur even when the operon is repressed in the presence of tryptophan
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