373226
Mutations
- various sorces
- lead to changes in the amino acid sequence
- can change cell function
- can change cell function
- not all mutations cause problems
- if hydrophobic amino acid changes to hydrophobic, no drastic change
- if hydrophobic amino acid changes to hydrophobic, no drastic change
- lead to changes in the amino acid sequence
- nonsense
- early stop codon
- shinks protein
- shinks protein
- early stop codon
- silent
- changes nucleotide that doesn't change amino acid specified codon
- changes genotype not phenotype
- changes nucleotide that doesn't change amino acid specified codon
- missense
- changes nucleotide that does
change amino acid specified
codon
- change in primary structure of protein
- changes nucleotide that does
change amino acid specified
codon
- frameshift
- addition/deletion of a nucleotide
- reading frame is shifted massive missense
- addition/deletion of a nucleotide
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