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4962791
DNA and RNA
Descripción
Leaving Certificate Biology Mapa Mental sobre DNA and RNA, creado por james liew el 28/03/2016.
Sin etiquetas
dna
rna
translation
transcription
amino acids
genetic screening
dna profiling
double helix
dna replication
biology
leaving certificate
Mapa Mental por
james liew
, actualizado hace más de 1 año
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Creado por
james liew
hace más de 8 años
379
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Resumen del Recurso
DNA and RNA
Structure of DNA
Nucleotides consists of a phosphate group, a sugar and a nitrogen-containing base
Four different bases
Adenine(A) and Guanine(G) are called purines
Thymine(T) and Cytosine(C) are called pyrimidines
"The Attorney General is Pure"
Sugar used in DNA is called Deoxyribose
Base Pair
Adenine and Thymine both form two weak hydrogen bonds
Guanine and Cytosine form three hydrogen bonds
The Double Helix
James Watson & Francis Crick
The double-stranded DNA molecule is wound into a double spiral
DNA Replication
Takes place in the nucleus during interphase
Results in a single-stranded chromosome forming two identical strands that are held together at the centromere
1: the double helix unwinds
2: enzymes break the hydrogen bonds
3: the complementary strands move apart
4: nucleotides move from cytoplasm into nucleus and attach to their complementary bases on the exposed strands
5: new strands contain exactly the same sequence of bases. Each new stretch of DNA re-forms into a double helix
The Genetic Code
A triplet is a sequence of three bases in a row
A codon is a triplet that acts as a code for an amino acid
Genes are composed of long sequences of DNA bases. Genes cause a sequence of amino acids to be assembled to form a protein
DNA Profiles
A DNA profile is a unique pattern of DNA from one person that is compared with the DNA profile of another person
1: DNA Isolation: DNA is extracted using a type of detergent which breaks down the cell and nucleus, releasing the DNA
2: Cut the DNA into Fragments using a restriction enzyme
3: Separate the Fragments based on their lengths using process called gel electrophoresis. DNA places into a el and electric current is applied
Uses of DNA profile
Crime
Medical
Paternity
Genetic Screening
Genetic Screening is a test of a person's DNA to see if an altered gene is present
Mutated genes are the cause of many genetic disorders such as:
Cystic Fibrosis (where fluid can't be removed from lungs)
Albinism (inability to form the pigment melanin)
Ethical Problems
If an embryo has disorder, may encourage abortion
Insurance companies may be informed of results
RNA
CATGUT: where CATG are the bases in DNA, and U replaces T in RNA
Protein Synthesis
Protein Synthesis is the making of protein using amino acids and the code in mRNA
Transcription is converting the code on DNA to a code on mRNA
Translation is converting the code from RNA to form a protein
1: double helix unwinds at site of gene that is to form protein
2: Transcription occurs, sequences of bases on DNA used to form a complementary strand of mRNA
3: mRNA strand moves out of nucleus into cytoplasm
4: mRNA strand moves into a ribosome
5: large number of tRNA molecules in cytoplasm, each carries a specific amino acid
6: Triplets/codons on mRNA attract complementary triplets on tRNA molecules
7: Amino acids are detached from their tRNA and bonded together in ribosomes to form a new protein
8: protein folds into correct 3D shape to function properly
Recursos multimedia adjuntos
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