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50343
Cardiovascular
Descripción
Bio 235 Mapa Mental sobre Cardiovascular, creado por Susy Sanchez el 19/04/2013.
Sin etiquetas
bio 235
bio 235
Mapa Mental por
Susy Sanchez
, actualizado hace más de 1 año
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Creado por
Susy Sanchez
hace más de 11 años
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Resumen del Recurso
Cardiovascular
Blood Vessels
Arterioles
Arteries
Oxygen Rich Blood
Stores pressure produced by ventricles & released via elastic recoil
Carry blood away from heart
Lg Arteries
Aorta and pulmonary trunk
Elastic fibers
Expand with blood pressure
Recoil with relaxation
Vascular resistance
Regulate flow
Oxygen Rich Blood
Vascular Resistance, Regulate flow
Highest % of smooth muscle
Diameter adjust with BP
reduced BF allows for efficient gas exchange at capillaries
Smallest arterioles regulate blood pressure
Capillaries
smallest blood vessels
Endothelial cell thick
Slow smooth muscle flow
Gas exchange
Types of capillaries
Continuous
Endothelial cells tight joined
Found:Muscle lungs
Fenestrated
Wide intercellular pores
Found:kidneys,intestines
Discontinuous
Sinusoidal
Large leaky
found in spleen, bone marrow
Fluid Exchange
Bulk Flow
Absoprion
fluid movement into capillaries
At venous end
wastes fluid back to the capillaries
Mass movement as a result of:
Hydrostatic pressure
Osmotic pressure
determines what comes in & out
Filtration
Movement out of capillaries
caused by hydrostatic Pressure
at Arterial end
Stuff moving out
Metarterioles
Short vessel
Links arterioles & capillaries
Individual muscle cells
Placed short distance apart
each forms capillary sphincter
Routes of Transport
Phospholipid bilayer
Intr. capillary clefts
Fenestrations
Pinocytotic
vesicles lg,molecules
small H2O soluble
small-H2O soluble
lipid-soluble molecule
Veins
Oxygen poor blood
More numerous
Large diameters
Hold more than 50% of blood
Carry blood to the heart
Very compliant
Little smooth muscle or elastin
Contain very low pressure
Insufficient to return blood to the heart
Low pressure requires special adaptations
Skeletal muscle pump
Muscle press against veins
Respiratory Pump
Sucking effect
Inspiration results in:
increases blood volume
increased arterial pressure
= decreased in arterial presure
One way valves
Venous valves
Measurement of Blood Pressure
120/80
Systolic/Diastolic
BP in artery
Constrict arteries to stop flow
Open valves
Allows arteries to open
blood hits walls
Thumping sound
=Systolic Pressure
Don't hear anything?
=Diastolic Pressure
MAP
Function of CO and resistance
MAP=CO X R
Control of BP
Baroreceptors
responsible to increase BP
response to orthostatic Hypertension
Low BP
Sense pressure change
Found in
Aorta
Vagus nerve
Carotid Artery
Medulla
Glassopharyngeal
What cause heart attack
Coronary artery
are blocked
No blood supply
Tissues dies
No nutrients or O2
Artherosclerosis
Inflammatory reaction
tear in arterial wall
Recruitment of clotting factors and leukocytes
Production of Proinflammatory cytokines
CPR
Adhesion of cholesterol
Hemostasis
Damaged Endothelium
Platelets bind to collagen
Platelets release eeaction
PRR
ADP
Serotonin
Thromboxane
sends signal for more platelets
Vasoconstrics
Sticky
Result
Vasoconstriction
Platelet chemotaxis
Sticky platelets
not making VMF
Healthy Endothelium
Platelets dont stick
Platelets produce
Prostacyclin
NO
CD39
ADP-AMP
Inhibits platelets aggregation
promotes vasodilatation
Platelet Aggregation
1. Sticky Platelet attached to collagen
2.triggered another platelet to release reaction
3. Platelet adhere to platelet
RESULT
Platelet Plug (sea)
Clot Dissolution
Vessel is repaired
Kallikrein, UPA, and TPA convert plasminogen into plasmin
Plasmin dissolves clot by digestion of fibrin
Clotting disorders
VWD
insufficient amount of VWF
Failure of platelet adhesion
Most common bleeding disorder
Hemophilia
Lack of clotting factors VII or Vx
X-linked gene
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