55476
Lecture one
- Drug
- A chemical
- The active
ingredient of
a medicine
- Any
substance
that can
affect living
processes
Interact with a
biological
system and
change it
- A chemical
- Pharmacology
- The study of
the mechnism
of drug action
- their development
- their uses
- their
adverse
effects
- their
benefical
effects
- their development
- The study of
the mechnism
of drug action
- Ages of Pharmacology
- 2000 BC - Egyptains
- Opium,
caster oil
- Femur from
a hanged
man
- Opium,
caster oil
- 460-377BC - Hippocartes
- Ethics of Medicine
- Willow Bark
- Ethics of Medicine
- 57 AD - Dioscorides
- Materia medica
(log/book/reference)
of 500 plants and
remedies
- Materia medica
(log/book/reference)
of 500 plants and
remedies
- 130-201AD Galen
- Theory
of
disease
- Theory
of
disease
- 980 - 1037 AD
- Abu Ali Al
Hussain Ibn Sina
- Canon
of
Medicine
- Pharmacy
and Surgery
- Canon
of
Medicine
- Abu Ali Al
Hussain Ibn Sina
- 1439-1541
- Paracelsus
- “The dose
maketh the
poison”
- Critical of
polypharmacy
- “The dose
maketh the
poison”
- Paracelsus
- 18th Century
- increase
use of
chemical
agents
- Ether
- Chloroform
- Nitrous oxide
- Ether
- increase
use of
chemical
agents
- 19th Century
- increase
systematic
scientific activity in
many disciplines
- Detailes and
Reliable Botanical
Records
- Isolation of pure
Compounds
- Morphione
Isolated in
1805
- Morphione
Isolated in
1805
- Developments in
physiology
- Finding
the site
of the
drug
- Action of
NMJ
blockers
- Action of
NMJ
blockers
- Finding
the site
of the
drug
- Detailes and
Reliable Botanical
Records
- increase
systematic
scientific activity in
many disciplines
- 2000 BC - Egyptains
- Subdivisions of Pharmacology
- Pharmacodynamics
- The study of
the effects of
drugs
- The study of
the effects of
drugs
- Pharmacokinetics
- The study
of the
movements
of drugs
- The study
of the
movements
of drugs
- Toxiocology
- The study of poisons
- The study of poisons
- Neuropharmacology
- The study of
the
pharmacoogy
of nervous
system
- The study of
the
pharmacoogy
of nervous
system
- Immunopharmacology
- The study of
Pharmacology of the
immune system
- The study of
Pharmacology of the
immune system
- Pharmacodynamics
- Pharmacologists
- assess
drug
efficacy
- determine the
possible adverse
effects of the drug
- determine the
likely effects of
overdose
- determine
the risks of
tolerance
and addition
- determine
the speed
of onset of
action
- determine the
duration of
action and the
route of the
drug's
metabolism
and excertion
- assess
drug
efficacy
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