Michael Jardine
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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

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Michael Jardine
Creado por Michael Jardine hace alrededor de 7 años
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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

Pregunta 1 de 6

1

Which of the following is NOT a type of Calcium channel?

Selecciona una de las siguientes respuestas posibles:

  • G-type

  • L-type

  • N-type

  • T-type

Explicación

Pregunta 2 de 6

1

An L-type Calcium channel has how many subunits?
(each controlled by a separate gene)

Selecciona una de las siguientes respuestas posibles:

  • 2

  • 3

  • 4

  • 5

  • 6

  • 7

  • 8

Explicación

Pregunta 3 de 6

1

An L-type Calcium channel is highly selective for Calcium, but is also somewhat permeable to Sodium and Potassium.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 4 de 6

2

During diastole, the Na/Ca exchanger and the SR Ca pump both move Ca. Which way around?

Selecciona una de las siguientes respuestas posibles:

  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back INTO the SR.

  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.

  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back INTO the SR.

  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.

Explicación

Pregunta 5 de 6

3

Selecciona la opción correcta de los menús desplegables para completar el texto.

The longitudinal SR contains a high concentrations of proteins acting as an ATP-dependent Ca pump - returning Ca from the myoplasm to the SR lumen (to help terminate contraction).
These proteins are called SERCA.
What does SERCA stand for?
( Sarco, Sarcoplasmic ) ( Endo, Endoplasmic ) ( [plasmic] Reticulum, [plasmic] Ryanodine ) ( Calcium, Concentration ) ( Activation, Activator, Adjustment, ATPase )

Explicación

Pregunta 6 de 6

1

The role that Phospholamban plays in regulation of the SR Ca pump is:

Selecciona una de las siguientes respuestas posibles:

  • Inhibitory; cancelled when phosphorylated.

  • Inhibitory; reinforced when phosphorylated.

  • Permissive; cancelled when phosphorylated.

  • Permissive; reinforced when phosphorylated.

Explicación

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