PHSI3011 13-1 Circadian Rhythm and Disease

1

The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?

1

The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?

1

Deepest sleep [normally] occurs at what time?

1

Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:

2

Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:

1

Free-Running Disorder (FRD) is:

1

The endogenous cycle is how many hours?

1

Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:

1

Treatments of human circadian rhythm disorders include:

1

Disruption of circadian rhythms can lead to:

PHSI3011 13-1 Circadian Rhythm and Disease

PHSI3011 13-1 Circadian Rhythm and Disease

The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?

The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?

Deepest sleep [normally] occurs at what time?

Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:

Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:

Free-Running Disorder (FRD) is:

The endogenous cycle is how many hours?

Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:

Treatments of human circadian rhythm disorders include:

Disruption of circadian rhythms can lead to:

True or false: Circadian rhythm disruptions have been linked to cancer.