HTN,Lipid Meds

1

T or F. African Americans respond better to a Thiazide diuretic.

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T or F. Beta blockers are 1st line drugs for HTN.

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Select all that apply. Which of the following are thiazide diuretics.

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Which class of diuretics inhibits distal convoluted tubule sodium and chloride re-absorption?

1

Select all that apply. Which of the following electrolyte imbalances can occur with thiazide diuretics?

1

Chlorthalidone and indapamide, are longer acting thiazide diuretics, more potent than HCTZ and carry a higher risk for hypokalemia.

1

A dose of HCTZ greater than _____mg has an increased risk for hypokalemia.

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What should the NP monitor when a patient is on thiazide diuretics? Select all that apply.

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T or F. Thiazide diuretics are commonly combined with other anti-hypertensives.

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T or F. Thiazide diuretics are contraindicated in persons with gout as they increase uric acid.

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T or F. Loop diuretics are used more often for edema than HTN.

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The following are exemplar Loop Diuretics:

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Identify the MOA for loop diuretics from the choices below:

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Loop diuretics are contraindicated in patients with:

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Loop diuretics:

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T or F. Potassium Sparing Diuretics have weak diuretic activity.

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Exemplars of Potassium Sparing Diuretics Includes: (select all that apply)

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Spironolactone:

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Lisinopril should be d/c if serum K+ increases more than?

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Which ACE is not used often for maintenance therapy d/t a short half-life and multiple dosing?

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If a patient is at high risk for renal artery stenosis, how soon after initiating ACEI should the patient's Cr be checked?

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Which patient populations have a greater risk of developing angioedema with the use of ACEI? Select all that apply.

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ACEI therapy is preferred for the following populations (select all that apply):

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ACEI and ARBS can have the following additional positive effects (select all that apply):

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What is a possible inconvenient but not life threatening adverse reaction from ACEI therapy?

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ACEI can increase K+

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An increase in Cr with ACEI therapy is often transient.

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What is the most common adverse reaction to ACEI therapy?

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The following are exemplars for ARBS (select all that apply)

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ARBS prevent the binding of Angiotensin II to receptors in the kidneys, brain, heart and arterial walls-inhibit RAAS and cause fall in peripheral resistance.

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ARBS may never be combined with which class of drug?

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ACEI and ARBS should be avoided in:

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ARBS can be a good choice for patients with Gout because:

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T or F. ARBS can raise serum K+.

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The Direct Renin Inhibitor Tekturna shares this possible side effect with ACEI.

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T or F. Tekturna can increase serum K+.

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T or F. ARBS are contraindicated in patients with Renal Artery Stenosis.

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T or F. You can combine ACEI, ARBS and DRI.

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The following is true of dihydropyridine CCB (select all that apply):

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Dihyropyridine CCB include (select all that apply)

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T or F. Peripheral edema can be caused by amlodipine.

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Which class of drugs can be combined with Amlodipine to reduce peripheral edema?

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Dihyrdopyridine CCB have greater efficacy in African Americans.

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T or F. ACEI can never be prescribed to African Americans.

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The following is true of non-dihyrdopyridine CCB (select all that apply):

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T or F. Verapamil has the strongest inotropic effect of the non-dihyrdopyridine CCB and should be avoided in patients with Heart Failure.

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Verapamil can interact with the following (select all that apply):

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T or F. Beta blockers are 1st line in the treatment of HTN.

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Cardio-selective beta-blockers include (select all that apply):

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Propranolol is a non-cardioselective beta-blocker that is used for symptom management with which endocrine issue:

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T or F. CCB and Beta-blockers can used for prophylactic treatment of migraines.

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T or F. Beta-blockers are superior protection against stroke.

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An example of mixed alpha and beta blocker is:

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What is major consideration when prescribing a beta-blocker in a patient with DM?

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In a patient with decompensated bronchospastic disease with stable angina, the NP should prescribe:

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S/E of beta-blockers can include (select all that apply):

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T or F. Discontinuation of beta-blockers needs to occur over a few weeks.

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Clonodine belongs to which class of anti-hypertensives?

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Centrally acting agents can be used to treat which condition in pediatric patients.

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Possible Adverse Reactions to Centrally Acting Agents includes (select all that apply):

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T or F. Patients wanting to come off of clonidine need to be tapered due to risk for rebound HTN.

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Methyldopa is indicated in which population?

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A contraindication for Methyldopa is:

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T or F. The MOA of methyldopa is it stimulates the Alpha 2 adrenergic receptors.

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Prazosin a peripherally acting agent, while not a 1st line anti-hypertensive is effective in treating:

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T or F. Doxazosin should be taken at bedtime due to risk for postural lightheadedness.

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The following should be avoided in pregnancy (select all that apply):

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In addition to methyldopa, which two other drugs are commonly used for HTN in pregnancy:

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T or F. Betablockers are not recommended as initial therapy in children.

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Which class of diuretics is used in fluid volume overload?

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When using Digoxin to treat Stage C Heart Failure, the NP knows which medicine can upset the narrow therapeutic index of the drug:

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T or F. Digoxin increases myocardial contractility.

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The therapeutic index for digoxin is:

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T or F. Low K+ and Mg+ and high Ca+ increase the risk for digoxin toxicity.

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Signs of toxicity to tell your patient who is taking digoxin are (select all that apply):

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HMG CoA reductase inhibitors are more commonly known as:

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The primary treatment goal of statins is to:

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T or F. It is fine for pregnant women or women planning to become pregnant to take simvastatin.

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Which group of patients could benefit from statins:

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Statins should be discontinued if which lab value if it is >3x the normal value?

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There is an increased risk of myopathy/rhabdomyolysis with which drug interactions:

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What lab level should be checked if a patient complains of muscle pain while taking a statin?

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T or F. New onset DM is less common with pravastatin and pitavastatin.

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Before changing a patient to new statin. the NP should ensure the patient has been adhering to their current statin medication by checking:

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T or F. Short acting statins like Lovastatin should be taken at bedtime?

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Lower doses of rosuvastatin is recommended in which population?

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One of the advantages of zetia over statins is:

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T or F. The MOA of Zetia is the inhibition of cholesterol at the small intestine.

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PCSK9 Inhibitors like Alirocumab and Evolocumab:

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T or F. Alirocumab must be stored in the refrigerator.

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T or F. PCSK9 inhibitors should be avoided in pregnancy.

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What is one way to decrease the flushing side effect that can come with the use of Niacin?

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T or F. Fibrates are only taken to reduce high triglycerides.

1

Gemfibrozil and Fenofibrate should not be taken with statins because:

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Fibrates should be avoided in (Select all that apply)

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Test Prep for Pharm

HTN,Lipid Meds

T or F. African Americans respond better to a Thiazide diuretic.

T or F. Beta blockers are 1st line drugs for HTN.

Select all that apply. Which of the following are thiazide diuretics.

Which class of diuretics inhibits distal convoluted tubule sodium and chloride re-absorption?

Select all that apply. Which of the following electrolyte imbalances can occur with thiazide diuretics?

Chlorthalidone and indapamide, are longer acting thiazide diuretics, more potent than HCTZ and carry a higher risk for hypokalemia.

A dose of HCTZ greater than _____mg has an increased risk for hypokalemia.

What should the NP monitor when a patient is on thiazide diuretics? Select all that apply.

T or F. Thiazide diuretics are commonly combined with other anti-hypertensives.

T or F. Thiazide diuretics are contraindicated in persons with gout as they increase uric acid.

T or F. Loop diuretics are used more often for edema than HTN.

The following are exemplar Loop Diuretics:

Identify the MOA for loop diuretics from the choices below:

Loop diuretics are contraindicated in patients with:

Loop diuretics:

T or F. Potassium Sparing Diuretics have weak diuretic activity.

Exemplars of Potassium Sparing Diuretics Includes: (select all that apply)

Spironolactone:

Lisinopril should be d/c if serum K+ increases more than?

Which ACE is not used often for maintenance therapy d/t a short half-life and multiple dosing?