Lecture 22 Limbic System

Key functions of limbic system:

T/F: All cortex of limbic system are neocortex.

Septal nuclei is excited by the transmitters.

The ventral tegmental area is regulated by the _______ transmitters.

The locus ceruleus is regulated by the _______ transmitters.

The raphe nuclei are regulated by the _________ transmitters.

The medial cortical region of limbic system is called the ________.

T/F: Most association fibers of limbic system run in one direction.

Name the structure that serves the following function:
1. smell
2. emotion and drives
3. establishing new memories
4. homeostasis

The limbic system is a collection of cortical gyri buried within the __________.

Key gyri in limbic system:

Hyppocampal formation are located (superficial/deep) to the parahippocampal gyri.

Anterior to the hippocampal formation is the _________.

Structure responsible for:
1. conscious detection of smell
2. ordor discrimination

the _________ of the parahippocampal gyrus is an important target for the emotional
and memory aspect of smell.

The ________ forms explicit memory.

What are considered as 'explicit memory'?

Location of hippocampal formation

Three parts of the hippocampal formation

T/F: All hippocampal formation are neocortex

Which three layers of cells are in the hippocampal formation?

The _______ and _______ folds twice.

The hippocampus forms the ___ of lateral ventricle in the _____ horn.

The parahippocampal gyrus ends up on the _____ surface of the medial temporal cortex, around the _______.

Uncus is _______ with mammilary bodies.

Many neocortical areas project to the entorhinal cortex, which projects to the _______ gyrus via _______.

The perforant pathway (or indirect perforant pathway) is important for _________

3 layers of dentate gyrus from outer to inner

The perforant pathway from entorhinal input synapse with the ____ cells in the dentate gyrus

Granule cell axons ( _______ fibers) from dentate gyrus project to the _____ and synapse on _____ pyramidal cells.

CA3 axons are called the

CA3 axons project to _____ neurons.

T/F: CA3---CA1 pathway is also long-term potentiation pathway.

Entorhinal cortex also have direct pathway to _____ and _____ pyramidal cells in the hippocampus. This pathway is called _______.

The direct perforant pathway leads back to _____ and ______.

Feedback loops run from ____ to _____ and then to _______.

The hippocampus and subiculum also form output paths to limbic system, thalamus, and hypothalamus via ________

Fornix is a white matter tract formed by the axons from _______ and ______ which are directed into the _____.

Fibers crossing between hemispheres are called ________. It is continuous with the (anterior/posterior) fornix.

Non-decussating fornix fibers either
1) bend and descend behind the _____ and end up in the __________.
2) bend and direct anterior to the anterior commissure and terminate in the _________, which is related to our ______ system.

Fornix fibers to mammillary bodies -->

T/F: the fornix pathway is bi-directional.

Outline the Papez circuit

___________ has a dominant role in emotional aspect of olfaction.

What happens to the patient if amygdala has lesion?

S/S of hyperactive amygdala

Connections the amygdala has

What are the 3 primary pathways of the amygdala?

position of stria terminalis

What does the stria terminalis carry?

The ventral amygdalofugal pathway projects to ______, _____ and _____ to support emotion, drive, and cognitive functions, and to ______ to impact homeostasis and arousal.

The median forebrain bundle carries ________, _____ and ______ fibers to nuclei under ________ control.

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